Molecular Medicine An Introduction.

Detalles Bibliográficos
Autor principal: Kurreck, Jens
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newark : John Wiley & Sons, Incorporated, 2016.
Colección:New York Academy of Sciences Ser.
Temas:
Electronic books.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Related Titles
  • Title Page
  • Copyright
  • Dedication
  • Preface
  • Acknowledgments
  • Chapter 1: Introduction
  • 1.1 The Basics of Molecular Medicine
  • 1.2 The Human Cell
  • 1.3 DNA Replication and Gene Expression
  • 1.4 Biological Communication
  • 1.5 The Immune System
  • References
  • Chapter 2: Methods in Molecular Medicine
  • 2.1 DNA Microarrays
  • 2.2 Quantitative Polymerase Chain Reaction
  • 2.3 Next-Generation Sequencing
  • 2.4 Animal Models in Biomedical Research
  • 2.5 Additional Methods
  • References
  • Chapter 3: Genetic Disorders
  • 3.1 Single-Gene Disorders
  • 3.2 Polygenic Disorders
  • References
  • Chapter 4: Molecular Oncology
  • 4.1 Molecular Biology of Breast Cancer and Its Clinical Implications
  • 4.2 Lung Cancer
  • 4.3 Hepatocellular Carcinoma
  • 4.4 Molecular Biology of Colorectal Cancer and Its Clinical Implications
  • 4.5 Molecular Biology of Renal Cell Carcinoma
  • 4.6 Molecular Biology of Prostate Cancer
  • 4.7 Molecular Biology of Hematological Malignancies
  • References
  • Chapter 5: Molecular Virology
  • 5.1 The Basics of Virology
  • 5.2 Vaccination
  • 5.3 Detection of Viruses
  • 5.4 Antiviral Therapy
  • 5.5 Prions
  • References
  • Chapter 6: Bacteria and Eukaryotic Pathogens
  • 6.1 Bacteria
  • 6.2 Eukaryotic Pathogens
  • References
  • Chapter 7: Genomics and Proteomics
  • 7.1 Whole Genome Sequencing
  • 7.2 The Human Genome
  • 7.3 Proteomics
  • References
  • Chapter 8: Genetic Testing
  • 8.1 Types of Genetic Tests
  • 8.2 Chromosome Abnormalities
  • 8.3 Molecular Diagnosis
  • References
  • Chapter 9: Pharmacogenetics/Pharmacogenomics
  • 9.1 Uptake and Transport of Drugs
  • 9.2 Drug Metabolism
  • 9.3 Drug Targeting
  • 9.4 Drug Toxicity and Hypersensitivity
  • 9.5 Drug Development and Individual Pharmacotherapy
  • References
  • Chapter 10: Recombinant Protein Drugs
  • 10.1 Production of Recombinant Proteins
  • 10.2 Classes of Recombinant Drugs
  • References
  • Chapter 11: Gene Therapy
  • 11.1 Types of Gene Therapy
  • 11.2 Methods of Gene Transfer
  • 11.3 Tissue Specificity of Gene Transfer and Gene Expression
  • 11.4 Applications of Gene Therapy
  • 11.5 Future Prospects
  • References
  • Chapter 12: Stem Cells
  • 12.1 Embryonic Stem Cells
  • 12.2 Adult Stem Cells
  • 12.3 Induced Pluripotent Stem Cells
  • 12.4 Transdifferentiation and Direct Reprogramming
  • 12.5 Differentiation of Stem Cells
  • 12.6 Medical Applications of Stem Cells
  • References
  • Chapter 13: Antisense, Ribozyme, and RNA Interference Strategies
  • 13.1 Antisense Oligonucleotides
  • 13.2 Ribozymes
  • 13.3 RNA Interference
  • 13.4 MicroRNAs
  • References
  • Chapter 14: Aptamers
  • 14.1 Selection of Aptamers
  • 14.2 Modifications of Aptamers
  • 14.3 Clinical Development of Aptamers
  • 14.4 Decoy and Immunostimulatory Oligonucleotides
  • References
  • Chapter 15: Ethics in Molecular Medicine
  • 15.1 The Basis of Bioethics
  • 15.2 Fields of Application
  • Abbreviations
  • Glossary
  • Index
  • End User License Agreement

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