Receptor Biology

Detalles Bibliográficos
Autor principal: Roberts, Michael F.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newark : John Wiley & Sons, Incorporated, 2016.
Colección:New York Academy of Sciences Ser.
Temas:
Electronic books.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover
  • Title Page
  • Copyright
  • Dedication
  • Contents
  • Acknowledgment
  • Part I Introduction
  • Chapter 1 Introduction
  • 1.1 Receptors and Signaling
  • 1.1.1 General Aspects of Signaling
  • 1.1.2 Verbal and Physiological Signals
  • 1.1.3 Criteria for Recognizing Transmitters and Receptors
  • 1.1.4 Agonists
  • 1.1.5 Receptors
  • 1.1.6 Receptor-Enzyme Similarities
  • 1.2 Types of Receptors and Hormones
  • 1.2.1 Receptor Superfamilies
  • 1.3 Receptors Are the Chemical Expression of Reality
  • Chapter 2 The Origins of Chemical Thinking
  • 2.1 Overview of Early Pharmacological History
  • 2.1.1 The Development of a Chemical Hypothesis
  • 2.1.2 Chemical Structure and Drug Action
  • 2.1.3 The Site of Drug Action
  • 2.2 Modern Pharmacology
  • 2.2.1 Langley and Ehrlich: the Origins of the Receptor Concept
  • 2.2.2 Maturation of the Receptor Concept
  • 2.3 Phylogenetics of Signaling
  • 2.3.1 The First Communicators
  • Part II Fundamentals
  • Chapter 3 Membranes and Proteins
  • 3.1 Membranes
  • 3.1.1 The Cytoplasmic Membrane
  • the Importance of Cell Membranes
  • 3.1.2 History of Membrane Models
  • 3.1.2.1 The Roles of Proteins in Membranes
  • 3.1.2.2 Challenges to the Danielli-Davson Model
  • 3.1.2.3 A New View of Membrane Proteins
  • 3.1.2.4 The Modern Concept of Membranes
  • the Fluid Mosaic Model
  • 3.1.3 Membrane Components
  • 3.1.3.1 Membrane Lipids
  • 3.1.3.2 Asymmetry and Heterogeneity in Membrane Lipids
  • 3.1.3.3 Membrane Construction and Insertion of Proteins
  • 3.2 The Nature and Function of Proteins
  • 3.2.1 Linear and Three-Dimensional Structures
  • 3.2.2 Primary Structure
  • 3.2.3 Secondary Structure
  • 3.2.4 Tertiary Structure
  • 3.2.5 Protein Domains
  • 3.2.6 Proteomics
  • Chapter 4 Hormones as First Messengers
  • 4.1 Hormones and Cellular Communication
  • 4.1.1 Discovery of Hormones
  • 4.2 Types of Hormones
  • 4.2.1 Pheromones for Signaling between Individuals
  • 4.2.2 Archaea and Bacteria
  • 4.2.3 Eukaryotes
  • 4.2.3.1 Chromalveolates
  • 4.2.3.2 Unikonts
  • Amoebozoa, Fungi, Animals
  • 4.2.3.3 Invertebrate Pheromones
  • 4.2.3.4 Vertebrate Pheromones
  • 4.3 Vertebrate Hormones and Transmitters
  • 4.3.1 Peptide and Non-Peptide Agonists
  • 4.3.1.1 Peptides
  • 4.3.1.2 Non-peptides
  • 4.3.2 Peptide Hormones of the G-Protein-Coupled Receptors
  • 4.3.2.1 Hypothalamic-Pituitary Axis
  • 4.3.2.2 The Anterior Pituitary Trophic Hormones
  • 4.3.3 Other Neural Peptides
  • 4.3.3.1 Opioids
  • 4.3.3.2 Non-Opioid Transmitter Peptides
  • 4.3.4 Peptides from Non-Neural Sources
  • 4.3.4.1 Digestive Tract Hormones
  • 4.3.4.2 Hormones from Vascular Tissue
  • 4.3.4.3 Hormones from the Blood
  • 4.3.4.4 Peptide Hormones from Reproductive Tissues
  • 4.3.4.5 Hormones from Other Tissues
  • 4.3.5 Non-Peptides Acting on G-Protein-Coupled Receptors
  • 4.3.5.1 Transmitters Derived from Amino Acids
  • 4.3.5.2 Transmitters Derived from Nucleotides
  • 4.3.5.3 Transmitters Derived from Membrane Lipids
  • Prostaglandins and Cannabinoids

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