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General and Molecular Pharmacology Principles of Drug Action.

Detalles Bibliográficos
Autor principal: Clementi, Francesco
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newark : John Wiley & Sons, Incorporated, 2015.
Colección:New York Academy of Sciences Ser.
Temas:
Acceso en línea:Texto completo

MARC

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020 |a 9781118768594 
020 |a 1118768590 
035 |a (OCoLC)1347024978 
082 0 4 |a 615.1/9  |q OCoLC  |2 23/eng/20230216 
049 |a UAMI 
100 1 |a Clementi, Francesco. 
245 1 0 |a General and Molecular Pharmacology  |h [electronic resource] :  |b Principles of Drug Action. 
260 |a Newark :  |b John Wiley & Sons, Incorporated,  |c 2015. 
300 |a 1 online resource (785 p.). 
490 1 |a New York Academy of Sciences Ser. 
500 |a Description based upon print version of record. 
505 0 |a Intro -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- SECTION 1 INTRODUCTION TO PHARMACOLOGY -- CHAPTER 1 ESSENTIAL LEXICON OF PHARMACOLOGY -- THE SOCIAL IMPACT OF PHARMACOLOGY -- ESSENTIAL LEXICON -- Active Substances -- Pharmacological Disciplines -- Drug-Receptor Interactions -- Measure of the Clinical Response -- TAKE-HOME MESSAGE -- CHAPTER 2 A SHORT HISTORY OF PHARMACOLOGY -- BIRTH AND HISTORICAL DEVELOPMENTS OF PHARMACOLOGY -- From Magical and Natural Remedies of Ancient Medicine to Arabic Alchemy -- From Monastic Medicine to Botanical Gardens 
505 8 |a From Anatomical Renaissance to the "Experienz": Paracelsus' Spagyric -- From Iatrochemistry to the Age of Enlightenment -- From the Search of the Active Principle to the Discovery of Alkaloids and Glucosides -- The Drug Synthesis Revolution: From Handmade to Industrial Production -- MODERN PHARMACOLOGY -- Ehrlich and Chemotherapy: The Concept of Receptor -- The Birth of Modern Pharmacology -- THE BIOTECHNOLOGY ERA AND THE PHARMACOLOGY IN THE THIRD MILLENNIUM -- The Impact of New Biotechnologies: Molecular Biology, Bioinformatics, and Combinatorial Chemistry 
505 8 |a Biological Drugs and Pharmacology Perspectives -- Personalized Therapies and New Sceneries in Pharmaceutical Industry -- TAKE-HOME MESSAGE -- FURTHER READING -- SECTION 2 GETTING THE DRUG TO ITS SITE OF ACTION -- CHAPTER 3 CELLULAR BASIS OF PHARMACOKINETICS -- A QUICK JOURNEY WITH THE DRUG IN THE BODY -- Absorption -- Distribution -- Drug Elimination -- CROSSING CELL MEMBRANES -- Passive Diffusion across Cell Membranes -- Drug Transport across Cell Membranes -- Endocytosis -- DRUG DIFFUSION TO ORGANS AND TISSUES -- Properties of the Most Important Cell Barriers -- TAKE-HOME MESSAGE 
505 8 |a FURTHER READING -- CHAPTER 4 DRUG ABSORPTION AND ADMINISTRATION ROUTES -- GENERAL RULES ABOUT DRUG ABSORPTION RATE -- Partition Coefficient -- Drug Dispersion -- Extension of the Absorbing Surface -- Permeability of the Absorbing Surface -- Vascularization -- ENTERAL ROUTES OF ADMINISTRATION -- Oral Route -- Sublingual and Rectal Routes -- SYSTEMIC PARENTERAL ROUTES OF ADMINISTRATION -- The Intravascular Route -- i.m. Injection -- Subcutaneous and Intradermal Injections -- OTHER ROUTES OF DRUG ADMINISTRATION -- Inhalation Route -- Topical/Regional Routes -- Intracavity Routes 
505 8 |a Dermal or Transcutaneous Route -- Mucosal Routes -- ABSORPTION KINETICS -- General Rules -- Interrelation between Gene Therapy and Drug Delivery Techniques -- TAKE-HOME MESSAGE -- FURTHER READING -- CHAPTER 5 DRUG DISTRIBUTION AND ELIMINATION -- DISTRIBUTION -- Tissues and Avidity for Drugs -- The Apparent Distribution Volume -- Drug Binding to Plasma Proteins -- Factors That Determine the Distribution Rate of Drugs to the Various Compartments -- ELIMINATION -- The Concept of Half-Life -- The Concept of Clearance -- RENAL EXCRETION OF DRUGS -- Glomerular Filtration 
500 |a Tubular Functions and Pharmacokinetics 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
655 0 |a Electronic books. 
758 |i has work:  |a General and molecular pharmacology (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCXBqQkcvrHWpGMftHrf4fV  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Clementi, Francesco  |t General and Molecular Pharmacology  |d Newark : John Wiley & Sons, Incorporated,c2015  |z 9781118768570 
830 0 |a New York Academy of Sciences Ser. 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=7104058  |z Texto completo 
938 |a ProQuest Ebook Central  |b EBLB  |n EBL7104058 
994 |a 92  |b IZTAP