Mass Spectrometry Principles and Applications.

Detalles Bibliográficos
Autor principal: de Hoffmann, Edmond
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newark : John Wiley & Sons, Incorporated, 2007.
Colección:New York Academy of Sciences Ser.
Temas:
Electronic books.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Mass Spectrometry
  • Contents
  • Preface
  • Introduction
  • Principles
  • Diagram of a Mass Spectrometer
  • History
  • Ion Free Path
  • 1 Ion Sources
  • 1.1 Electron Ionization
  • 1.2 Chemical Ionization
  • 1.2.1 Proton Transfer
  • 1.2.2 Adduct Formation
  • 1.2.3 Charge-Transfer Chemical Ionization
  • 1.2.4 Reagent Gas
  • 1.2.5 Negative Ion Formation
  • 1.2.6 Desorption Chemical Ionization
  • 1.3 Field Ionization
  • 1.4 Fast Atom Bombardment and Liquid Secondary Ion Mass Spectrometry
  • 1.5 Field Desorption
  • 1.6 Plasma Desorption
  • 1.7 Laser Desorption
  • 1.8 Matrix-Assisted Laser Desorption Ionization
  • 1.8.1 Principle of MALDI
  • 1.8.2 Practical Considerations
  • 1.8.3 Fragmentations
  • 1.8.4 Atmospheric Pressure Matrix-Assisted Laser Desorption Ionization
  • 1.9 Thermospray
  • 1.10 Atmospheric Pressure Ionization
  • 1.11 Electrospray
  • 1.11.1 Multiply Charged Ions
  • 1.11.2 Electrochemistry and Electric Field as Origins of Multiply Charged Ions
  • 1.11.3 Sensitivity to Concentration
  • 1.11.4 Limitation of Ion Current from the Source by the Electrochemical Process
  • 1.11.5 Practical Considerations
  • 1.12 Atmospheric Pressure Chemical Ionization
  • 1.13 Atmospheric Pressure Photoionization
  • 1.14 Atmospheric Pressure Secondary Ion Mass Spectrometry
  • 1.14.1 Desorption Electrospray Ionization
  • 1.14.2 Direct Analysis in Real Time
  • 1.15 Inorganic Ionization Sources
  • 1.15.1 Thermal Ionization Source
  • 1.15.2 Spark Source
  • 1.15.3 Glow Discharge Source
  • 1.15.4 Inductively Coupled Plasma Source
  • 1.15.5 Practical Considerations
  • 1.16 Gas-Phase Ion-Molecule Reactions
  • 1.17 Formation and Fragmentation of Ions: Basic Rules
  • 1.17.1 Electron Ionization and Photoionization Under Vacuum
  • 1.17.2 Ionization at Low Pressure or at Atmospheric Pressure
  • 1.17.3 Proton Transfer
  • 1.17.4 Adduct Formation
  • 1.17.5 Formation of Aggregates or Clusters
  • 1.17.6 Reactions at the Interface between Source and Analyser
  • 2 Mass Analysers
  • 2.1 Quadrupole Analysers
  • 2.1.1 Description
  • 2.1.2 Equations of Motion
  • 2.1.3 Ion Guide and Collision Cell
  • 2.1.4 Spectrometers with Several Quadrupoles in Tandem
  • 2.2 Ion Trap Analysers
  • 2.2.1 The 3D Ion Trap
  • 2.2.2 The 2D Ion Trap
  • 2.3 The Electrostatic Trap or 'Orbitrap'
  • 2.4 Time-of-Flight Analysers
  • 2.4.1 Linear Time-of-Flight Mass Spectrometer
  • 2.4.2 Delayed Pulsed Extraction
  • 2.4.3 Reflectrons
  • 2.4.4 Tandem Mass Spectrometry with Time-of-Flight Analyser
  • 2.4.5 Orthogonal Acceleration Time-of-Flight Instruments
  • 2.5 Magnetic and Electromagnetic Analysers
  • 2.5.1 Action of the Magnetic Field
  • 2.5.2 Electrostatic Field
  • 2.5.3 Dispersion and Resolution
  • 2.5.4 Practical Considerations
  • 2.5.5 Tandem Mass Spectrometry in Electromagnetic Analysers
  • 2.6 Ion Cyclotron Resonance and Fourier Transform Mass Spectrometry
  • 2.6.1 General Principle
  • 2.6.2 Ion Cyclotron Resonance

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