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20240329122006.0 |
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230209s2016 xx o ||| 0 eng d |
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|a EBLCP
|b eng
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|d OCLCQ
|d OCLCO
|d EBLCP
|d OCLCQ
|d OCLCL
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|a 9781118876381
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|a 1118876385
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|a (OCoLC)1347023125
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|a 611/.0181663
|q OCoLC
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| 049 |
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|a UAMI
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| 100 |
1 |
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|a Herrera, Rene J.
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| 245 |
1 |
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|a Genomes, Evolution, and Culture
|h [electronic resource] :
|b Past, Present, and Future of Humankind.
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| 260 |
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|a Newark :
|b John Wiley & Sons, Incorporated,
|c 2016.
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| 300 |
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|a 1 online resource (267 p.).
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| 490 |
1 |
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|a New York Academy of Sciences Ser.
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| 500 |
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|a Description based upon print version of record.
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|a Genomes, Evolution,and CulturePast, Present, and Futureof Humankind -- Contents -- Preface -- Chapter 1: The history of human evolutionary genetics -- World views -- Science and philosophy -- The biology of mankind: anatomy and physiology in a historical context (up to the 16th century) -- Beginnings of the present scientific model -- Biological evolution and genetic foundations: the brilliant quartet -- Nineteenth century: cytology, embryology, and reproduction -- Twentieth century, the century of genetics -- The synthetic theory of evolution -- Bacterial and molecular genetics
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|a Parallel developments: paleoanthropology -- Technical and methodological developments -- Conclusions -- Review questions and exercises -- References -- Chapter 2: The human genome: structure, function, and variation -- Science, politics, and ethics -- Structural aspects -- Normal and abnormal phenotype distribution -- Function -- Sex chromosomes -- Paleogenomics -- Variability: mtDNA -- Nuclear variability -- Exomes and proteomes -- Selection or drift? History -- Selection or drift? Methods -- Selection or drift? Analyses -- Nervous system and culture -- Conclusions
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| 505 |
8 |
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|a Review questions and exercises -- References -- Chapter 3: Population structure -- DNA-based marker systems -- SNPs, STRs, and Indels as DNA markers -- SNPs -- STRs -- Indels -- Population genetic tools for analyzing population structure -- Forces affecting population dynamics, structure, and evolution -- Selection -- Genetic drift -- Migration and founder effect -- Isolation and inbreeding -- Nonrandom mating -- Bottlenecks -- Admixture -- Applications of population genetics -- Introduction -- Medicine -- Pharmacogenetics -- DNA fingerprinting -- From populations to races and species
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| 505 |
8 |
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|a Review questions and exercises -- References -- Chapter 4: Genetic variability -- On the nature of variability -- Mechanisms responsible for generating genetic variability -- Randomness of mutations -- Inheritance and environment -- Selection works on the phenotype -- The impact of selection -- Cultural expressions as markers of ancestry -- Congruency among marker systems -- Does junk DNA exist? -- How genetic diversity is studied? -- Epigenetic diversity -- Review questions and exercises -- References -- Chapter 5: Gene and genomic dynamics
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| 505 |
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|a Molecular evidence for punctuated equilibrium and gradualism -- Next-generation sequencing -- Genetic variation -- Variation, population structure, and effective population size -- Recombination and its effect on variation -- Linkage equilibrium and disequilibrium -- Forces leading to linkage disequilibrium -- Linkage disequilibrium and SNP haplotypes -- Linkage disequilibrium in humans -- Genome structural variations -- CNV classifications and formation mechanisms -- Methods used to detect CNVs -- CNVs associated with human phenotypes -- CNVs and evolution -- CNV in primates
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| 500 |
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|a Chromosome rearrangements and selfish genetic elements
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| 590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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| 655 |
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0 |
|a Electronic books.
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| 758 |
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|i has work:
|a Genomes, evolution, and culture (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCFRjHF4WDq93FRbgfPb9j3
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
| 776 |
0 |
8 |
|i Print version:
|a Herrera, Rene J.
|t Genomes, Evolution, and Culture
|d Newark : John Wiley & Sons, Incorporated,c2016
|z 9781118876404
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| 830 |
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0 |
|a New York Academy of Sciences Ser.
|
| 856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=7104167
|z Texto completo
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| 938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL7104167
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| 994 |
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|a 92
|b IZTAP
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