Building Brains An Introduction to Neural Development.
Autor principal: | |
---|---|
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Newark :
John Wiley & Sons, Incorporated,
2011.
|
Colección: | New York Academy of Sciences Ser.
|
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Intro
- Title page
- Copyright
- Preface
- Conventions and Commonly used Abbreviations
- Naming conventions for genes and proteins
- Commonly used abbreviations
- Significance of bold and blue bold terms
- 1: Models and Methods for Studying Neural Development
- 1.1 What is neural development?
- 1.2 Why research neural development?
- 1.3 Major breakthroughs that have contributed to understanding developmental mechanisms
- 1.4 Invertebrate model organisms
- 1.5 Vertebrate model organisms
- 1.6 Observation and experiment: methods for studying neural development
- 1.7 Summary
- 2: The Anatomy of Developing Nervous Systems
- 2.1 The nervous system develops from the embryonic neuroectoderm
- 2.2 Anatomical terms used to describe locations in embryos
- 2.3 Development of the neuroectoderm of invertebrates
- 2.4 Development of the neuroectoderm of vertebrates and the process of neurulation
- 2.5 Secondary neurulation in vertebrates
- 2.6 Formation of invertebrate and vertebrate peripheral nervous systems
- 2.7 Summary
- 3: Neural Induction: An Example of How Intercellular Signalling Determines Cell Fates
- 3.1 What is neural induction?
- 3.2 Specification and commitment
- 3.3 The discovery of neural induction
- 3.4 A more recent breakthrough: identifying molecules that mediate neural induction
- 3.5 Conservation of neural induction mechanisms in Drosophila
- 3.6 Beyond the default model
- other signalling pathways involved in neural induction
- 3.7 Signal transduction: how cells respond to intercellular signals
- 3.8 Intercellular signalling regulates gene expression
- 3.9 The essence of development: a complex interplay of intercellular and intracellular signalling
- 3.10 Summary
- 4: Patterning the Neuroectoderm
- 4.1 Regional patterning of the nervous system
- 4.2 Patterning the anteroposterior (AP) axis of the Drosophila CNS
- 4.3 Patterning the AP axis of the vertebrate CNS
- 4.4 Refining AP axis patterning within regions and segments
- 4.5 Patterning the dorsoventral (DV) axis of the nervous system
- 4.6 Bringing it all together
- 4.7 Summary
- 5: Neurogenesis: Generating Neural Cells
- 5.1 Generating neural cells
- 5.2 Neurogenesis in Drosophila
- 5.3 Neurogenesis in vertebrates
- 5.4 The regulation of neuronal subtype identity
- 5.5 The regulation of cell proliferation during neurogenesis
- 5.6 Temporal regulation of neural identity
- 5.7 Why do we need to know about neurogenesis?
- 5.8 Summary
- 6: Neuronal Migration
- 6.1 Many neurons migrate long distances during formation of the nervous system
- 6.2 How can neuronal migration be observed?
- 6.3 Major modes of migration
- 6.4 Initiation of migration
- 6.5 How are migrating cells guided to their destinations?
- 6.6 Locomotion
- 6.7 Journey's end
- termination of migration
- 6.8 The mechanisms that govern migration of important populations of cortical neurons remain unknown
- 6.9 Summary