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00000cam a2200000Mu 4500 |
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EBOOKCENTRAL_on1273974178 |
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OCoLC |
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20240329122006.0 |
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m o d |
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cr ||||||||||| |
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211009s2020 pau o ||| 0 eng d |
040 |
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|a EBLCP
|b eng
|c EBLCP
|d REDDC
|d OCLCF
|d OCLCQ
|d OCLCO
|d OCLCL
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020 |
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|a 9781975124816
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020 |
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|a 1975124812
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035 |
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|a (OCoLC)1273974178
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050 |
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4 |
|a RC281.C4
|b .P599 2021
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082 |
0 |
4 |
|a 618.92994
|2 23
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049 |
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|a UAMI
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100 |
1 |
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|a Blaney, Susan M.
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245 |
1 |
0 |
|a Pizzo and Poplack's Pediatric Oncology
|h [electronic resource].
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250 |
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|a 8th ed.
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260 |
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|a Philadelphia :
|b Wolters Kluwer Health,
|c 2020.
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300 |
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|a 1 online resource (3044 p.)
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500 |
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|a Description based upon print version of record.
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505 |
0 |
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|a Title Page -- Copyright Page -- Section 1 Biological Basis of Childhood Cancer -- 1 Epidemiology of Childhood Cancer -- Cancer Surveillance and Descriptive Epidemiology -- Analytic Epidemiology -- Summary and Future Considerations -- 2 Heredity and Childhood Cancer -- Constitutional Chromosomal Abnormalities -- Structural Chromosomal Abnormalities -- Overgrowth Disorders and Imprinting Errors -- Autosomal Dominant Disorders -- Autosomal Recessive Disorders -- Issue in Genetic Testing for the Pediatric Oncology Patient -- 3 Molecular and Genetic Basis of Childhood Cancer
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505 |
8 |
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|a General Nature of Cancer-Associated Genetic Aberrations -- Comprehensive Analysis of the Cancer Genome -- Germline Mutations -- Somatically Acquired Chromosomal Aberrations and Mutation -- Gross Chromosomal Rearrangements -- Oncogenic Consequences of Gross Chromosomal Rearrangements-General Themes -- Chromosomal Translocations Lead to Activation of Proto-Oncogenes and Generation of Oncogenic Fusion Genes -- Chromosomal Deletion Leads to Inactivation of Tumor Suppressor Genes -- Gene Amplification -- Point Mutations Leading to Gene Activation or Inactivation
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505 |
8 |
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|a Comprehensive Genomic Studies of Pediatric Tumors -- Mechanisms of Malignant Cell Transformation, Growth, and Clonal Expansion -- Outlook for Molecularly Targeted Therapies -- Summary -- 4 Biology of Childhood Cancer -- Gene Regulation -- Protein Regulation -- Signal Transduction -- Cell Proliferation -- Programmed Cell Death -- Cancer Metabolism -- Metastasis and the Tumor Microenvironment -- 5 Tumor Immunology of Childhood Cancer -- Overview of the Immune System -- Modern Concepts of Immune Surveillance -- T-Cell Recognition of Cancer -- Innate Immune Cells and the Tumor Microenvironment
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505 |
8 |
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|a Immune Function in Cancer Patients -- Immunotherapy of Cancer -- Summary and Future Directions -- Section 2 Diagnosis and Evaluation of the Child with Cancer -- 6 Clinical Assessment and Differential Diagnosis of Suspected Childhood Cancer -- Children at Risk -- Time to Diagnosis -- Differential Diagnosis -- Establishing the Diagnosis -- Summary -- 7 Pathology and Molecular Diagnosis of Leukemias and Lymphomas -- Introduction -- Ancillary Studies -- Lymphoblastic Leukemia -- Myeloid Neoplasms -- Mature Lymphoid Neoplasms -- Histiocytic Disorders
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505 |
8 |
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|a 8 Diagnostic Pathology of Pediatric Solid and Central Nervous System Malignancies -- Introduction -- Brief Pathologic Classification of Pediatric Solid Tumors -- Traditional Approaches to Childhood Solid Tumor Diagnosis -- Molecular Genetic Evaluation of Childhood Cancer -- Integrated Diagnostic Molecular Pathology of Pediatric Solid Tumors -- The Holistic Cancer Genome -- DNA -- RNA -- Emerging Technologies for Diagnosis -- The Future of Pediatric Cancer Diagnosis -- 9 Imaging Studies in the Diagnosis of Childhood Cancer -- Relative Merits of Available Imaging Procedures
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500 |
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|a General Concepts of Pediatric Tumor Imaging.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
|
650 |
|
0 |
|a Tumors in children.
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650 |
|
7 |
|a Tumors in children
|2 fast
|
700 |
1 |
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|a Helman, Lee J.
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700 |
1 |
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|a Adamson, Peter C.
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758 |
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|i has work:
|a Principles and practice of pediatric oncology (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCFKXJhj4T6PHRtxGD6YhVC
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
8 |
|i Print version:
|a Blaney, Susan M.
|t Pizzo and Poplack's Pediatric Oncology
|d Philadelphia : Wolters Kluwer Health,c2020
|z 9781975124793
|
856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=6743415
|z Texto completo
|
938 |
|
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|a ProQuest Ebook Central
|b EBLB
|n EBL6743415
|
994 |
|
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|a 92
|b IZTAP
|