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In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Weber, Lisa Annabel
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Göttingen : Cuvillier Verlag, 2021.
Colección:Wissenschaftliche Reihe der Klinik für Pferde.
Temas:
Acceso en línea:Texto completo

MARC

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008 210612s2021 gw o ||| 0 eng d
040 |a EBLCP  |b eng  |c EBLCP  |d N$T  |d OCLCF  |d OCLCQ  |d OCLCO  |d OCLCL 
020 |a 3736964323 
020 |a 9783736964327  |q (electronic bk.) 
035 |a (OCoLC)1256237389 
050 4 |a SF959.S54 
082 0 4 |a 636.108965  |2 23/eng/20220829 
049 |a UAMI 
100 1 |a Weber, Lisa Annabel. 
245 1 0 |a In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark  |h [electronic resource]. 
260 |a Göttingen :  |b Cuvillier Verlag,  |c 2021. 
300 |a 1 online resource (141 p.). 
490 1 |a Wissenschaftliche Reihe der Klinik für Pferde ;  |v v.51 
500 |a Description based upon print version of record. 
505 0 |a Intro -- LIST OF ABBREVIATIONS -- SUMMARY -- ZUSAMMENFASSUNG -- 1. Introduction -- 1.1. The equine malignant melanoma -- 1.2. The equine sarcoid: an overview -- 1.3. Topical drug application -- 1.4. Naturally occurring substances in plane bark and their syntheticallymodified derivatives -- 1.5. Hypotheses and aims of the thesis -- 2. Manuscript I:Betulinic acid shows anticancer activity against equine melanoma cells andpermeates isolated equine skin in vitro -- 2.1. Supplemental data 
505 8 |a 3. Manuscript II:In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate asa topical treatment for equine skin cancer -- 4. Manuscript III:Concentration profiles and safety of topically applied betulinic acid andNVX-207 in eight healthy horses -- A randomized, blinded, placebocontrolled,crossover pilot study -- 5. Manuscript IV:Effects of topically applied betulinic acid and NVX-207 on early stageequine melanoma -- A prospective, randomized, double-blind, placebocontrolledpilot study -- 6. General discussion -- 6.1. Summarized findings -- 6.2. Interpretation of the findings 
505 8 |a 7. Major findings and conclusions -- 8. Future perspectives -- 9. References -- Affidavit -- Acknowledgements 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Horses  |x Diseases. 
650 0 |8 7\p  |a Skin  |x Cancer. 
650 0 |8 8\p  |a Bark. 
650 6 |a Chevaux  |x Maladies. 
650 6 |a Peau  |x Cancer. 
650 6 |a Écorce. 
650 7 |a bark (plant material)  |2 aat 
650 7 |a Bark  |2 fast 
650 7 |a Horses  |x Diseases  |2 fast 
650 7 |a Skin  |x Cancer  |2 fast 
758 |i has work:  |a In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCG7YjGfxhDqbHHkG43m9Tb  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Weber, Lisa Annabel  |t In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark  |d Göttingen : Cuvillier Verlag,c2021  |z 9783736974326 
830 0 |a Wissenschaftliche Reihe der Klinik für Pferde. 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=6636881  |z Texto completo 
938 |a ProQuest Ebook Central  |b EBLB  |n EBL6636881 
938 |a EBSCOhost  |b EBSC  |n 2942402 
994 |a 92  |b IZTAP