Micro- and Macroparticle enhanced cultivation of filamentous Lentzea aerocolonigenes for increased rebeccamycin production

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Schrinner, Kathrin
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Göttingen : Cuvillier Verlag, 2020.
Colección:Schriftenreihe des Institutes für Bioverfahrenstechnik der Technischen Universität Braunschweig.
Temas:
Biology.
Biologie.
biology.
Biology
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • 1 Introduction and aim of the thesis
  • 2 Theoretical background
  • 2.1 Lentzea aerocolonigenes and rebeccamycin
  • 2.2 Morphology and productivity of filamentous microorganisms
  • 2.3 Bubble-free aeration in bioreactors
  • 3 Material and methods
  • 3.1 Strain and cultivation medium
  • 3.2 Particles
  • 3.3 Cultivation methods
  • 3.4 Analytical methods
  • 3.5 Investigation of the pellet structure
  • 4 Results and discussion
  • 4.1 Microparticle enhanced cultivation
  • 4.2 Macroparticle enhanced cultivation
  • 4.3 Membrane aerated stirred bioreactor cultivations
  • 4.4 Particle-based rebeccamycin recovery with adsorbent resins
  • 5 Conclusions and future prospects
  • 6 List of abbreviations and symbols
  • 7 References

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