Vascularization in Tissue Engineering

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Vascularization in Tissue Engineering presents a comprehensive picture of blood vessel development and the recent developments on the understanding of the role of angiogenesis in regenerating biological tissues. The first-half of this book, consists of three chapters, emphasizing the fundamental kno...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Cai, Xiaoxiao
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : Bentham Science Publishers, 2020.
Temas:
Tissue engineering.
Neovascularization.
Tissue Engineering
Neovascularization, Pathologic
Génie tissulaire.
Néovascularisation.
Neovascularization
Tissue engineering
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover
  • Title
  • Copyright
  • End User License Agreement
  • Contents
  • Preface
  • Foreword
  • List of Contributors
  • Biological Basis of Vascularization
  • Yichen Ge, Yuting Wen and Xiaoxiao Cai*
  • 1. INTRODUCTION OF BIOLOGICAL VASCULARIZATION
  • 1.1. Vasculogenesis
  • 1.1.1. Embryonic Vasculogenesis
  • 1.1.2. Postpartum Vasculogenesis
  • 1.1.3. Vasculogenesis in Reparative Process
  • 1.2. Angiogenesis
  • 1.2.1. Introduction of Angiogenesis
  • 1.2.2. Branching, Maturation and Resting of Blood Vessels in Angiogenesis
  • 2. BIOLOGICAL MOLECULES
  • 2.1. The VEGF Family
  • 2.2. PDGF Family
  • 2.3. Angiopoietin
  • 2.4. The bFGF and The FGF Superfamily
  • 2.5. Integrins and Proteases
  • 2.6. Junctional Molecules
  • 3. THE MARKERS AND TESTING OF ANGIOGENESIS
  • 3.1. Markers in Extracellular Matrix
  • 3.1.1. Fibronectin
  • 3.1.2. Polysaccharide
  • 3.1.3. Promoting Factor
  • 3.1.4. Related Proteases
  • 3.1.5. Specific Substance Produced by Angiogenesis
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Effects of Microenvironment Factors on Angiogenesis
  • Changyue Xue and Xiaoxiao Cai*
  • 1. INTRODUCTION
  • 2. EFFECT OF EXTRACELLULAR MATRIX ON ANGIOGENESIS IN TISSUE ENGINEERING
  • 2.1. Properties of the Extracellular Matrix of Vessels
  • 2.2. Role of Matrix Stiffness in Regulating Endothelial Cells Behaviour
  • 2.3. Role of Matrix Stiffness in Regulating Angiogenesis
  • 2.4. Underlying Mechanism of Matrix Stiffness on Angiogenesis
  • 2.4.1. Mechanosensing and Mechanotransduction
  • 2.4.2. Expression of Functional Proteins and Growth Factors
  • 3. EFFECT OF FLUID SHEAR FORCE ON ANGIOGENESIS
  • 4. EFFECT OF MICROPATTERNS OF SUBSTRATE MATERIALS ON ANGIOGENESIS
  • 5. EFFECT OF CELL LOADING STRESS ON ANGIOGENESIS
  • 6. EFFECT OF NITRIC OXIDE LEVEL ON ANGIOGENESIS
  • CONCLUDING REMARKS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Microenvironment of Pathological Vascularization
  • Mei Zhang and Xiaoxiao Cai*
  • 1. INTRODUCTION
  • 2. PATHOLOGICAL CONDITIONS LEADING TO ADVERSE VASCULARISATION
  • 2.1. Inflammation-Related Diseases and Angiogenesis
  • 2.1.1. Inflammation-Related Diseases and Angiogenesis
  • 2.1.2. Pathological Mechanism of Inflammatory Angiogenesis
  • 2.1.3. Consequence of Inflammatory Angiogenesis
  • 2.2. Vascularization Under Ischemia
  • 2.2.1. Ischemic Diseases and Angiogenesis
  • 2.2.2. Pathological Mechanism of Ischemic Angiogenesis
  • 2.2.3. Consequence of Ischemic Angiogenesis
  • 2.3. Vascularization Under Hypoxia
  • 2.3.1. Hypoxic Disease and Angiogenesis
  • 2.3.2. Pathological Mechanism of Hypoxic Angiogenesis
  • 2.4. Vascularization Under Senility
  • 2.4.1. Pathological Mechanism of Aging Angiogenesis
  • 2.4.2. The Consequences of Impaired Angiogenesis
  • 3. CHARACTERISTICS OF ABNORMAL BLOOD VESSELS
  • 3.1. Abnormal Vascular Structure and Dysfunction

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