Oil-In-Water Nanosized Emulsions for Drug Delivery and Targeting

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Shunmugaperumal, Tamilvanan
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newark : John Wiley & Sons, Incorporated, 2020.
Temas:
Drug delivery systems.
Emulsions.
Oils and fats > Solubility.
Drug Delivery Systems
Emulsions
Systèmes d'administration de médicaments.
Émulsions.
Huiles et graisses > Solubilité.
emulsion.
Drug delivery systems
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover
  • Title Page
  • Copyright Page
  • Contents
  • LIST OF CONTRIBUTORS
  • FOREWORD
  • PREFACE
  • CHAPTER 1 INTRODUCTION: AN OVERVIEW OF NANOSIZED EMULSIONS
  • 1.1. INTRODUCTION
  • 1.2. CONCLUSION
  • REFERENCES
  • CHAPTER 2 FORMULATION DEVELOPMENT OF OIL-IN-WATER NANOSIZED EMULSIONS
  • 2.1. INTRODUCTION
  • 2.2. FDA-APPROVED OILS, EMULSIFIERS, AND AUXILIARY OR MISCELLANEOUS EXCIPIENTS
  • 2.3. CURRENT AND NEAR FUTURE DIRECTION
  • 2.4. LIPOPHILIC API INCORPORATION PATTERN INTO NANOSIZED EMULSIONS
  • 2.5. QbD APPROACH TO OPTIMIZE EMULSION
  • 2.6. CONCLUSION
  • REFERENCES
  • CHAPTER 3 CHARACTERIZATION AND SAFETY ASSESSMENT OF OIL-IN-WATER NANOSIZED EMULSIONS
  • 3.1. INTRODUCTION
  • 3.2. PHYSICAL AND VISUAL EVALUATIONS
  • 3.3. CHEMICAL AND BIOLOGICAL EVALUATIONS
  • 3.4. SAFETY AND EFFICACY ASSESSMENTS
  • 3.5. CONCLUSION
  • REFERENCES
  • CHAPTER 4 MANUFACTURING AND POSITIONING (GENERATIONS) OF OIL-IN-WATER NANOSIZED EMULSIONS
  • 4.1. INTRODUCTION
  • 4.2. GENERATIONS OF O/W NANOSIZED EMULSIONS
  • 4.3. PREPARATION METHODS FOR API-FREE/LOADED O/W NANOSIZED EMULSIONS
  • 4.4. CONCLUSION
  • REFERENCES
  • CHAPTER 5 BIOFATE OF NANOSIZED EMULSIONS
  • 5.1. INTRODUCTION
  • 5.2. BIOFATE OF O/W NANOSIZED EMULSIONS
  • 5.3. CLINICAL ISSUES OF FIRST-GENERATION NANOSIZED EMULSIONS
  • 5.4. CONCLUSION
  • REFERENCES
  • CHAPTER 6 MEDICAL OR THERAPEUTICAL APPLICATIONS OF OIL-IN-WATER NANOSIZED EMULSIONS
  • 6.1. INTRODUCTION
  • 6.2. MEDICAL OR THERAPEUTICAL APPLICATIONS OF O/W NANOSIZED EMULSIONS
  • 6.3. CONCLUSION
  • REFERENCES
  • PART I OVERVIEW OF TOCOL-BASED EMULSIONS, OXYGEN-CARRYING EMULSIONS, EMULSIONS WITH DOUBLE OR TRIPLE CARGOS AND EMULSION-LIKE DISPERSIONS
  • CHAPTER 7 OVERVIEW OF TOCOL-BASED EMULSIONS, OXYGEN-CARRYING EMULSIONS, EMULSIONS WITH DOUBLE OR TRIPLE CARGOS AND EMULSION-LIKE DISPERSIONS
  • CHAPTER 7.1 TOCOL-BASED NANOSIZED EMULSIONS
  • 7.1.1. INTRODUCTION
  • 7.1.2. FORMULATION DEVELOPMENT USING TOCOL
  • 7.1.3. NON- AND PRE-CLINICAL SAFETY STUDIES
  • 7.1.4. THERAPEUTIC APPLICATIONS
  • 7.1.5. CONCLUSION
  • REFERENCES
  • CHAPTER 7.2 OXYGEN-CARRYING EMULSIONS
  • 7.2.1. INTRODUCTION
  • 7.2.2. RATIONALE FOR SELECTING PERFLUOROCARBON FOR IN VIVO OXYGEN TRANSPORT
  • 7.2.3. FORMULATION OF STABLE INJECTABLE PERFLUOROCARBON EMULSIONS
  • 7.2.4. MULTIFUNCTIONAL PERFLUOROCARBON-BASED EMULSIONS
  • 7.2.5. GENERATIONS AND HURDLES OF PERFLUOROCARBON-BASED NANOSIZED EMULSIONS AS OXYGEN CARRIERS
  • 7.2.6. PROPOSED SOLUTIONS TO OVERCOME THE HURDLES OF PERFLUOROCARBON-BASED NANOSIZED EMULSIONS USED AS OXYGEN CARRIERS
  • 7.2.7. CONCLUSION
  • REFERENCES
  • CHAPTER 7.3 NANOSIZED EMULSIONS FOR MULTIPLE MEDICAMENT LOADINGS, IMAGING, AND THERANOSTIC PURPOSES
  • 7.3.1. INTRODUCTION
  • 7.3.2. BRIEF REVIEW OF RESEARCH REPORTS ON NANOSIZED EMULSIONS FOR IMAGING AND THERANOSTIC PURPOSE

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