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Mechanisms of Vascular Defects in Diabetes Mellitus

This book comprising 24 chapters is devoted to the mechanisms for the pathogenesis of the spectrum of vascular diseases in diabetes. Cellular events and molecular pathways that regulate the structure and function of both small and large arteries, the dysregulation in these vessels caused by hypergly...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Kartha, C.C (Editor ), Ramachandran, Surya (Editor ), Pillai, Radhakrishna M. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2017.
Edición:1st ed. 2017.
Colección:Advances in biochemistry in health and disease ; 17.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Section 1 Introduction
  • The Global Burden Of Diabetes And Its Vascular Complications
  • SECTION 2 Pathogenesis
  • Genetic Basis For Increased Risk For Vascular Diseases In Diabetes
  • Vascular Remodelling In Diabetes Mellitus
  • Pathogenesis Of The Plaque Vulnerability In Diabetes Mellitus
  • Endothelial Dysfunction In Diabetes
  • Smooth Muscle Cells In Diabetes Mellitus
  • Monocytes Factors In Pathogenesis Of Vascular Lesions In Diabetes
  • Endothelial Progenitor Cell Dysfunction In The Pathogenesis Of Vascular Complications Of Diabetes
  • Pathogenetic mechanisms in diabetic retinopathy: from molecules to cells to tissues
  • Perspectives on the vascular pathogenesis of diabetic neuropathy
  • SECTION 3 Molecular mechanisms
  • The Renin
  • Angiotensin System And Diabetes
  • Adipokines And Vascular Disease In Diabetes
  • G-Proteins In Vascular Complications Of Diabetes
  • Histone Deacetylases In Vascular Pathophysiology: Regulation By Vasoactive Peptides And Growth Factors
  • Role of non-coding RNAs in vascular complications of diabetes mellitus
  • SECTION 4 Hemostatic Factors
  • Diabetes As A Prothrombotic State
  • Mechanisms Of Hypercoagulation And Aberrant Clot Lyses In Type 2 Diabetes
  • Platelet Dysfunction In Type-2 Diabetes Mellitus
  • SECTION 5 Metabolic Factors
  • Advanced Glycation End Products In Diabetic Complications
  • Atherogenicdyslipoproteinemia In Type 2 Diabetes Mellitus
  • Vascular Remodeling: Homocysteine And Diabetes
  • SECTION 6 Pharmacological Therapies
  • Mechanisms Of Action Of Drugs For Treating Endothelial Dysfunction In Diabetes Mellitus
  • Beneficial Effects Of Inorganic Nitrate/Nitrite On Vascular Function And Blood Pressure In Diabetes
  • Myeloperoxidase (MPO): Do We Need Inhibitors?.