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200428s2020 nju ob 001 0 eng d |
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|a 2020018394
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|a UKAHL
|b eng
|e rda
|c UKAHL
|d EBLCP
|d OCLCO
|d REDDC
|d OCLCF
|d OCLCQ
|d OCLCO
|d OCLCL
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|a 1155329877
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|a 9781119640257
|z 9781119640196
|q (cloth)
|q (e-book)
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|a 1119640253
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|z 9781119640257
|q (adobe pdf)
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|z 9781119640264
|q (epub)
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|a (OCoLC)1159412228
|z (OCoLC)1155329877
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|a RS201.B54
|b .B563 2020
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|a 615.1
|2 23
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|a UAMI
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|a Bioadhesives in drug delivery
|c edited by K.L. Mittal, I.S. Bakshi and J.K. Narang.
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250 |
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|a First edition.
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264 |
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1 |
|a Hoboken, NJ :
|b Wiley-Scrivener,
|c 2020.
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300 |
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|a 1 online resource
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490 |
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|a Adhesion and Adhesives: Fundamental and Applied Aspects Ser.
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505 |
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|a Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Part 1 Fundamental Aspects -- Chapter 1 Introduction, Theories and Mechanisms of Bioadhesion -- 1.1 Introduction -- 1.1.1 Historical Perspective -- 1.1.2 Bioadhesion in Biological Systems -- 1.1.3 Bioadhesive/Mucoadhesive -- 1.1.4 Factors Affecting Mucoadhesion -- 1.1.4.1 Molecular Weight of Polymer -- 1.1.4.2 Concentration of Polymer Used -- 1.1.4.3 Flexibility of Polymer Chains -- 1.1.4.4 Swelling -- 1.1.4.5 pH at Polymer-Mucus Interface -- 1.1.4.6 Mucin Turnover Rate -- 1.1.4.7 Stereochemistry -- 1.2 Bioadhesive Interactions
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|a 1.3 The Mechanistic Approach to Bioadhesion -- 1.4 Factors Controlling Bioadhesion -- 1.4.1 Chemical Interactions -- 1.4.1.1 Mussel Adhesion -- 1.4.1.2 Cell Adhesion to Biomaterials -- 1.4.2 Surface Morphology Effects -- 1.4.3 Physiological Factors -- 1.4.4 Physical and Mechanical Factors -- 1.4.4.1 Wetting Phenomenon -- 1.4.4.2 Interpenetration -- 1.5 Theories of Bioadhesion -- 1.5.1 Wetting Theory -- 1.5.2 Diffusion Theory -- 1.5.3 Electronic Theory -- 1.5.4 Adsorption Theory -- 1.5.5 Fracture Theory -- 1.6 Stages of Mucoadhesion -- 1.7 Modulation of Mucoadhesion -- 1.8 Adhesion Promoters
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|a 1.9 Surface Free Energy Analysis of Bioadhesion -- 1.10 Molecular Biology in Bioadhesion -- 1.11 Bioadhesives from Marine Sources -- 1.12 Mucoadhesive Drug Delivery Systems -- 1.13 Summary -- References -- Chapter 2 Bioadhesive Polymers for Drug Delivery Applications -- 2.1 Introduction -- 2.1.1 Drug Delivery -- 2.2 Bioadhesive/Mucoadhesive Drug Delivery Systems -- 2.2.1 Some Advantages of the Bioadhesive/Mucoadhesive Drug Delivery Systems -- 2.2.2 The General Need for Bioadhesive/Mucoadhesive Drug Delivery Systems -- 2.3 Mechanism of Bioadhesion
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|a 2.4 Requirements for an Ideal Bioadhesive/ Mucoadhesive Polymer -- 2.5 Factors Affecting Bioadhesion/Mucoadhesion -- 2.5.1 Polymer Related Factors -- 2.5.1.1 Molecular Weight -- 2.5.1.2 Chain Length -- 2.5.1.3 Flexibility -- 2.5.1.4 Cross-Linking -- 2.5.1.5 Presence of Functional Groups -- 2.5.1.6 Concentration of Active Polymer -- 2.5.2 Environmental Factors -- 2.5.2.1 pH and Charge on the Polymer -- 2.5.2.2 Degree of Hydration -- 2.5.2.3 Initial Contact Time -- 2.5.2.4 Applied Pressure -- 2.5.2.5 Swelling -- 2.5.2.6 Ionic Strength -- 2.5.2.7 Mucus Gel Viscosity -- 2.5.3 Physiological Factors
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|a 2.5.3.1 Mucin Turnover -- 2.5.3.2 Disease States -- 2.6 Bioadhesive Polymers for Drug Delivery Applications -- 2.6.1 Polymers -- 2.6.1.1 Natural Polymers -- 2.6.1.2 Synthetic Polymers -- 2.6.2 Bioadhesive/Mucoadhesive Polymers -- 2.6.3 Classification of Mucoadhesive Polymers -- 2.6.3.1 Classification Based on the Origin of the Polymer -- 2.6.3.2 Classification Based on Aqueous Solubility of the Polymer -- 2.6.3.3 Classification Based on the Type of Charge on the Polymer -- 2.6.4 Natural Polymers -- 2.6.4.1 Chitosan -- 2.6.4.2 Starch -- 2.6.4.3 Gelatin -- 2.6.4.4 Alginates
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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0 |
|a Bioadhesive drug delivery systems.
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650 |
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6 |
|a Systèmes bioadhésifs (Administration des médicaments)
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650 |
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7 |
|a Bioadhesive drug delivery systems
|2 fast
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700 |
1 |
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|a Mittal, K. L.,
|d 1945-
|e editor.
|1 https://id.oclc.org/worldcat/entity/E39PCjKv8H9WwJxmb89dhKchpd
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776 |
0 |
8 |
|i Print version:
|a Mittal, K. L.
|t Bioadhesives in Drug Delivery
|d Newark : John Wiley & Sons, Incorporated,c2020
|z 9781119640196
|
830 |
|
0 |
|a Adhesion and Adhesives: Fundamental and Applied Aspects Ser.
|
856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=6198568
|z Texto completo
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938 |
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|a Askews and Holts Library Services
|b ASKH
|n AH36662237
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938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL6198568
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994 |
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|a 92
|b IZTAP
|