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Biomarkers in drug discovery and development : a handbook of practice, application, and strategy /

"This book continues the legacy of a well-established reference within the pharmaceutical industry -- providing perspective, covering recent developments in technologies that have enabled the expanded use of biomarkers, and discussing biomarker characterization and validation and applications t...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Rahbari, Ramin, 1965- (Editor ), Van Niewaal, Jonathan, 1979- (Editor ), Bleavins, Michael R. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, NJ : John Wiley & Sons, Inc., 2020.
Edición:Second edition.
Temas:
Acceso en línea:Texto completo
Descripción
Sumario:"This book continues the legacy of a well-established reference within the pharmaceutical industry -- providing perspective, covering recent developments in technologies that have enabled the expanded use of biomarkers, and discussing biomarker characterization and validation and applications throughout drug discovery and development. Several case studies of biomarkers that have helped and hindered decision making are presented, as well as an overview of the areas where proper use of biomarkers can substantively impact timelines and costs by streamlining development programs, enabling selection of better compounds and reducing late stage attrition, and facilitating personalized medicine. The new edition updates existing information with developments in pre-clinical and clinical testing and introduces substantial new materials on data mining, decision making, and personal genetic tools. With such significant expansion and revision, the 2nd edition ensures Biomarkers in Drug Development remains a key resource for biotechnology and major pharmaceutical companies, and their efforts to improve and expedite drug development"--
Notas:Preceded by Biomarkers in drug development : a handbook of practice, application, and strategy / edited by Michael R. Bleavins [and others], 2010.
Descripción Física:1 online resource (xvi, 591 pages, 11 unnumbered pages of plates) : illustrations (some color)
Bibliografía:Includes bibliographical references and index.
ISBN:9781119187547
1119187540
9781119187516
1119187516