Cargando…
An investigation of microRNA target regulation mechanisms using an integrative approach /
Long description: This work is a showcase for the integration of systems biology and bioinformatics tools, algorithms and models for deciphering biological phenomena. More specifically, it integrates (i) prediction algorithms for identifying and characterizing molecular interactions, (ii) structural...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin :
Logos Verlag Berlin GmbH,
[2015]
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000Mi 4500 | ||
|---|---|---|---|
| 001 | EBOOKCENTRAL_on1139151397 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
| 006 | m o d | ||
| 007 | cr |n||||||||| | ||
| 008 | 200207s2015 gw a ob 000 0 eng d | ||
| 010 | |a 2016302448 | ||
| 040 | |a YDX |b eng |e pn |c YDX |d EBLCP |d OCLCQ |d REDDC |d OCLCO |d OCLCF |d K6U |d VT2 |d OCLCO |d SFB |d OCLCQ |d OCLCO | ||
| 019 | |a 1249241911 | ||
| 020 | |a 9783832587826 |q (electronic bk.) | ||
| 020 | |a 3832587829 |q (electronic bk.) | ||
| 020 | |z 9783832540050 |q (pbk.) | ||
| 020 | |z 3832540059 |q (pbk.) | ||
| 029 | 1 | |a AU@ |b 000068937808 | |
| 035 | |a (OCoLC)1139151397 |z (OCoLC)1249241911 | ||
| 041 | 0 | |a eng |b eng |b ger |m ger | |
| 050 | 4 | |a QP623 |b .S365 2015 | |
| 082 | 0 | 4 | |a 572.8/8 |
| 049 | |a UAMI | ||
| 100 | 1 | |a Schmitz, Ulf, |e author. | |
| 245 | 1 | 3 | |a An investigation of microRNA target regulation mechanisms using an integrative approach / |c vorgelegt von Ulf Schmitz. |
| 246 | 3 | |a Iinvestigation of micro RNA target regulation mechanisms using an integrative approach | |
| 264 | 1 | |a Berlin : |b Logos Verlag Berlin GmbH, |c [2015] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references (pages 159-176). | ||
| 546 | |a Text in English; summaries in English and German; translated from German. | ||
| 520 | |a Long description: This work is a showcase for the integration of systems biology and bioinformatics tools, algorithms and models for deciphering biological phenomena. More specifically, it integrates (i) prediction algorithms for identifying and characterizing molecular interactions, (ii) structural modelling of molecule complexes, (iii) network analysis approaches, and (iv) mathematical modelling and simulation. Two comprehensive workflows are implemented for the analysis of collective target gene regulation by microRNAs and for the prediction of cooperating microRNA pairs and their mutual target genes. In two case studies mechanisms of fine-tuned target gene regulation are revealed for different cellular processes and the phenomenon of cooperative target regulation is identified as frequent mechanism of gene regulation in humans. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a MicroRNA. | |
| 650 | 0 | |a RNA. | |
| 650 | 6 | |a MicroARN. | |
| 650 | 6 | |a ARN. | |
| 650 | 7 | |a MicroRNA |2 fast | |
| 650 | 7 | |a RNA |2 fast | |
| 776 | 0 | 8 | |i Print version: |a Schmitz, Ulf. |t Investigation of microRNA target regulation mechanisms using an integrative approach. |d Berlin : Logos Verlag Berlin GmbH, [2015] |z 9783832540050 |z 3832540059 |w (DLC) 2016302448 |w (OCoLC)915504324 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=6032825 |z Texto completo |
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL6032825 | ||
| 938 | |a YBP Library Services |b YANK |n 301085348 | ||
| 994 | |a 92 |b IZTAP | ||