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Bioinformatics and data analysis in microbiology /

This book provides invaluable, up-to-date and detailed information on various aspects of bioinformatics data analysis with applications to microbiology. It describes a number of different useful bioinformatics tools, makes links to some wet-lab techniques, explains different approaches to tackle a p...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Bishop, Ozlem Tastan (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Norfolk, UK : Caister Academic Press, [2014]
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Bioinformatics and data analysis in microbiology /  |c edited by Ozlem Tastan Bishop. 
264 1 |a Norfolk, UK :  |b Caister Academic Press,  |c [2014] 
300 |a 1 online resource :  |b illustrations (black and white, and colour) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
520 |a This book provides invaluable, up-to-date and detailed information on various aspects of bioinformatics data analysis with applications to microbiology. It describes a number of different useful bioinformatics tools, makes links to some wet-lab techniques, explains different approaches to tackle a problem, talks about current challenges and limitations, gives examples of applications of bioinformatics methods to microbiology, and discusses future trends. The chapters include topics such as genome sequencing techniques, assembly, SNP analysis, annotation, comparative genomics, microbial communi. 
504 |a Includes bibliographical references and index. 
505 0 |a Contributors; Preface; 1: Understanding the Unseen Majority Around Us: An Overview of Microbiological Technologies; Introduction; What is a microorganism?; Microbes in the world around us -- the unseen majority; Microorganisms and climate change; The impact of microorganisms in industry; Assessing microbial populations; DNA sequence determination; Bioinformatics analysis of sequence data; Application of molecular approaches to the study of microorganisms; Challenges in the field; Concluding remarks; 2: Prokaryotic Genome Sequencing and Assembly; Introduction; Sequencing technologies 
505 8 |a Sequence assemblyChoosing a sequencing and assembly strategy; Conclusions; 3: Genome-wide Variant Discovery Using Sequence Assembly, Mapping and Population-wide Analysis; Background; Microbial genetic variation and genome sequencing; Horizontally inherited DNA and genome sequencing; Alternative genotyping approaches; Genome assembly: methods, tools and improvement; Mapping and filtering DNA reads; Variant discovery using mapped reads; Detecting population-wide variation from mapped DNA reads; Genome-wide data analysis and future trends; Conclusions; 4: Prokaryotic Genome Annotation 
505 8 |a IntroductionGenome annotation; Automated annotation pipelines; Future trends; Conclusions; 5: Comparative Analysis of Microbial Pathogen Genomes to Study Unique Gene Families; Introduction; In silico comparative genomics applications in microbiology; Applications of comparative genomics to the study of Mycobacterium tuberculosis; Conclusions; Future trends; 6: Microbial Community Profiling: Current Approaches and Future Trends; Introduction; Genetic fingerprinting techniques; Data analysis; Unresolved questions and future trends; 7: Metagenomics and Microbiomes; Introduction 
505 8 |a Experimental design considerationsMarker gene experiments; Whole genome shotgun sequencing experiments; Metagenomic analyses of samples, genomic features, and metadata; Computational resources; Outlook; 8: Human Microbiome Analysis via the 16s rRNA Gene; Introduction; Microbiome exploration via whole genome shotgun and 16S sequencing; Low-resolution community profiling methods; Next-generation sequencing platform considerations; Potential sources of error and preprocessing; Chimera detection; Taxonomy assignment; Statistical analysis; Conclusion; 9: Phylogenetic Microarrays; Introduction 
505 8 |a Current phylogenetic microarraysOptimization of phylogenetic microarrays; Phylogenetic microarray applications; Future trends and outlook; 10: Genetic Barcoding of Bacteria and its Microbiology and Biotechnology Applications; The history of barcoding of microorganisms; 16S ribosomal RNA sequence -- a universal barcode of bacterial species; Multilocus sequence typing; DNA barcoding and next generation sequencing; Genetic barcoding in biotechnology; Conclusion; Index 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Microbiology  |x Data processing. 
650 0 |a Bioinformatics. 
650 0 |a Computational biology. 
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650 2 2 |a Computational Biology  |x methods 
650 2 |a Computational Biology 
650 6 |a Microbiologie  |x Informatique. 
650 6 |a Bio-informatique. 
650 7 |a Computational biology  |2 fast 
650 7 |a Bioinformatics  |2 fast 
650 7 |a Microbiology  |x Data processing  |2 fast 
700 1 |a Bishop, Ozlem Tastan,  |e editor. 
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