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|a 9781119285519
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|a (OCoLC)1096535339
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|b .C446 2019
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|a 615.19
|2 23
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|a UAMI
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|a Am Ende, David J.
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|a Chemical Engineering in the Pharmaceutical Industry, R & d to Manufacturing
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|a 2nd ed.
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|a Newark :
|b John Wiley & Sons, Incorporated,
|c 2019.
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|a 1 online resource (685 pages)
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|a text
|b txt
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|a computer
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|a Intro; TITLE PAGE; COPYRIGHT PAGE; CONTENTS; LIST OF CONTRIBUTORS; PREFACE; UNIT CONVERSIONS; PART I INTRODUCTION; CHAPTER 1 CHEMICAL ENGINEERING IN THE PHARMACEUTICAL INDUSTRY; 1.1 GLOBAL IMPACT OF THE INDUSTRY; 1.2 INVESTMENTS IN PHARMACEUTICAL R 1.3 BEST SELLERS; 1.4 PHARMACEUTICAL RESEARCH AND DEVELOPMENT EXPENDITURES; 1.5 RECENT TRENDS FOR PHARMACEUTICAL DRUG AND MANUFACTURING; 1.6 CHEMICAL ENGINEERS SKILLED TO IMPACT FUTURE OF PHARMACEUTICAL INDUSTRY; REFERENCES; PART II DRUG PRODUCT DESIGN, DEVELOPMENT, AND MODELING; CHAPTER 2 DESIGN OF SOLID DOSAGE FORMULATIONS; 2.1 INTRODUCTION
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|a 2.2 UNDERSTANDING DRUG SUBSTANCE2.3 EXCIPIENTS; 2.4 DRUG-EXCIPIENT COMPATIBILITY STUDY; 2.5 PROCESSING OF FORMULATIONS; 2.6 TABLET FORMULATION DESIGN; 2.7 TABLET CHARACTERISTICS; 2.8 USING DISSOLUTION TO DETERMINE CQAs; 2.9 DRUG PRODUCT STABILITY; 2.10 PROCESS OPERATIONS AND SCALABILITY OF DOSAGE FORM; 2.11 CONCLUDING REMARKS; REFERENCES; CHAPTER 3 POWDER PROCESS CHALLENGES AND SOLUTIONS; 3.1 INTRODUCTION; 3.2 COMMON POWDER-HANDLING EQUIPMENT; 3.3 POWDER FLOW AND SEGREGATION CONCERNS; 3.4 MEASUREMENT OF FLOW PROPERTIES
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|a 3.5 TROUBLE-SHOOTING POWDER-HANDLING PROBLEMS AND EQUIPMENT DESIGN METHODSREFERENCES; CHAPTER 4 DESIGN AND SCALE-UP OF DRY GRANULATION PROCESSES; 4.1 OVERVIEW OF THE DRY GRANULATION PROCESS; 4.2 GENERAL CONSIDERATIONS FOR ROLLER COMPACTION OPERATIONS AND EQUIPMENT; 4.3 MATERIAL BEHAVIOR, QUALITY ATTRIBUTES, AND TESTING; 4.4 PRINCIPLES OF OPERATION; 4.5 SCALE-UP OF ROLLER COMPACTION; 4.6 SUMMARY; REFERENCES; CHAPTER 5 MODEL-BASED DEVELOPMENT OF ROLLER COMPACTION PROCESSES; 5.1 INTRODUCTION; 5.2 ROLL COMPACTION; 5.3 MILLING
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|a 5.4 PROPERTY FUNCTIONS FOR MODEL-BASED DEVELOPMENT OF ROLLER COMPACTION5.5 CONNECTING PROCESS AND PROPERTY MODELS; 5.6 SUMMARY; 5.7 NOTATION; REFERENCES; CHAPTER 6 WET GRANULATION PROCESSES; 6.1 INTRODUCTION; 6.2 MECHANISMS IN WET GRANULATION; 6.3 SCALE-UP; 6.4 FUTURE DIRECTIONS; REFERENCES; CHAPTER 7 TOWARD A GENERIC MODEL FOR TWIN-SCREW WET GRANULATION; 7.1 INTRODUCTION; 7.2 EXPERIMENTAL DATA COLLECTION; 7.3 GRANULE SIZE DISTRIBUTIONS AT DIFFERENT LOCATIONS; 7.4 PBM MODEL DEVELOPMENT; 7.5 PBM MODEL CALIBRATION; 7.6 RESULTS FOR THE WETTING ZONE 1; 7.7 RESULTS FOR THE FIRST KNEADING ZONE 3
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|a 7.8 RESULTS FOR THE SECOND KNEADING ZONE 67.9 RESULTS OF DIRECT SIMULATION FROM PREBLEND TO FINAL GRANULES AT TSG OUTLET (ZONES 1-6); 7.10 OUTLOOK; REFERENCES; CHAPTER 8 MODELING A DOSATOR CAPSULE FILLING PROCESS FOR HARD-SHELL CAPSULES; 8.1 OVERVIEW OF THE DOSATOR CAPSULE FILLING PROCESS; 8.2 DEM MODEL OF THE DOSATOR PROCESS; 8.3 MODELING RESULTS FOR THE DOSATOR FILLING PROCESS; 8.4 CASE STUDY: PREDICTION OF OPTIMAL INSERTION DEPTH INTO THE POWDER BED DURING A DOSATOR FILLING PROCESS; 8.5 SUMMARY; REFERENCES; CHAPTER 9 POWDER COMPACTION; 9.1 INTRODUCTION
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|a 9.2 MECHANICS OF TABLET COMPRESSION: SIMPLE BEGINNINGS
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Biochemical engineering.
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650 |
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|a Chemical engineering.
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650 |
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|a Pharmaceutical technology.
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650 |
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2 |
|a Chemical Engineering
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|a Technology, Pharmaceutical
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650 |
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|a Génie biochimique.
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650 |
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|a Génie chimique.
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|a Techniques pharmaceutiques.
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650 |
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|a chemical engineering.
|2 aat
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650 |
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|a Biochemical engineering
|2 fast
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650 |
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7 |
|a Chemical engineering
|2 fast
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650 |
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|a Pharmaceutical technology
|2 fast
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700 |
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|a Am Ende, Mary Tanya.
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758 |
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|i has work:
|a Chemical engineering in the pharmaceutical industry (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGVcCCVCJxCMJ3Pmrcw8cq
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
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|i Print version:
|a Am Ende, David J.
|t Chemical Engineering in the Pharmaceutical Industry, R & d to Manufacturing.
|d Newark : John Wiley & Sons, Incorporated, ©2019
|z 9781119285496
|
856 |
4 |
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|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5744611
|z Texto completo
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938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL5744611
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994 |
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|a 92
|b IZTAP
|