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Mass spectrometry : an applied approach.
Provides a comprehensive description of mass spectrometry basics, applications, and perspectivesMass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, co...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, NJ :
Wiley,
2019.
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| Edición: | Second edition / |
| Colección: | Wiley-Interscience series on mass spectrometry.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Atmospheric pressure ionization (API) IV.1.3.01 Atmospheric pressure chemical ionization (APCI) IV.1.3.02 Electrospray (ESI) IV.1.3.02.1 Introduction IV.1.3.02.2 ESI principle of operation IV.1.3.02.3 ESI - working principles IV.1.3.02.4 Properties of the solvent IV.1.3.02.5 Principles of ESI-MS spectra interpretation IV.1.3.03 Nanoelectrospray (nanoESI) IV.1.3.03.1 Introduction IV.1.3.03.2 Nanospray sensitivity IV.1.3.03.3 Ionization in nanoelectrospray and electrospray ion sources IV.1.3.03.4 Off-line nanospray and practical advices IV.1.3.03.5 On-line nanospray and practical advices IV.1.3.03.6 Summary IV.1.3.04 Desorption electrospray ionization (DESI) IV.1.3.04.1 Introduction IV.1.3.04.2 Construction of the ion source IV.1.3.04.3 Principles of operation IV.1.3.04.4 Mechanism of ions formation IV.1.3.04.5 The role of surface for sample
- IV.1.7.03 The sputtering of the sample surface IV.1.7.04 Ionization (generating secondary ions) IV.1.7.05 Construction of TOF-SIMS IV.1.7.06 Analytical capabilities of TOF-SIMS IV.1.7.06.1 Static TOF-SIMS IV.1.7.06.2 Visualization of sample surface IV.1.7.06.3 Dynamic SIMS - in-depth analysis IV.1.7.07 Examples and spectra interpretation IV.1.7.07.1 Speciation analysis IV.1.7.07.2 Distribution of species on the surface IV.1.7.07.3 In-depth speciation analysis IV.2 Analyzers IV.2.1. Time-of-Flight (TOF) IV.2.1.01 Introduction IV.2.1.02 The working rule of TOF analyzer IV.2.1.03 Linear mode of operation of TOF IV.2.1.04 The spread of the kinetic energy regarding the ions of the same mass IV.2.1.05 Delayed ion extraction IV.2.1.06 The reflection mode IV.2.1.07 Orthogonal acceleration IV.2.1.08 Summary IV.2.2.
- Ion mobility analyzer (IM) IV.2.2.01 Principle of IM operation IV.2.2.02 Drift time IMS IV.2.2.03 FAIMS (high-field asymmetric waveform ion mobility spectrometer) IV.2.2.04 TWIG (travelling wave ion guides) IV.2.2.05 IM spectrum IV.2.2.06 Applications IV.2.3 Quadrupole mass analyzer (Q) IV.2.3.01 Construction and principles of operation of a quadrupole IV.2.3.02 Behavior of an ion inside the quadrupole IV.2.3.03 How mass spectrum is generated? Changes of U and V IV.2.3.04 Spectrum quality IV.2.3.05 Applications of the quadrupole analyzer IV.2.3.06 Quadrupoles, hexapoles and octapoles as focusing elements
- ion guides IV.2.4.
- Ion trap (IT) IV.2.4.01 Introduction IV.2.4.02 Behavior of an ion inside the ion trap IV.2.4.03 Analysis of the ions IV.2.4.04 Tandem in space Mass Selective Instability Mode IV.2.4.05 Resonant Ejection Mode IV.2.4.06 Axial Modulation IV.2.4.07 Nonlinear Resonance IV.2.4.08 Linear ion trap LIT IV.2.4.09 Applications IV.2.5. High resolution mass spectrometry IV.2.5.01 Introduction IV.2.6. Ion cyclotron resonance (ICR) IV.2.6.01 Introduction IV.2.6.02 Cyclotron frequency IV.2.6.03 ICR
- principles of operation IV.2.6.04 Injection of ions into the ICR cell IV.2.6.05 Trapping electrodes IV.2.6.06 Excitation electrodes IV.2.6.07 Detection electrodes and Fourier transform IV.2.6.08 FT-ICR properties as m/z analyzer IV.2.7.
- Hyphenated techniques V.1. Gas chromatography combined with mass spectrometry GC-MS V.1.1. Introduction V.1.2 Detectors V.1.3. Chemical modifications - derivatization V.1.4. GC-MS analysis V.1.5. Two-dimensional gas chromatography linked to mass spectrometry 2D GC-MS V.2. Liquid chromatography linked to mass spectrometry (LC-MS) V.2.1. Introduction V.2.2. Introduction to liquid chromatography V.2.3. Types of detectors V.2.4. Chromatographic columns V.2.5. Chromatographic separation and quantitation using MS as a detector V.2.6. Construction of an interface linking liquid chromatograph to the mass spectrometer V.2.6.01 Introduction V.2.6.02 ESI interface V.2.6.03 APCI connection to MS V.2.6.04 APPI inte