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Routledge handbook of sport and exercise systems genetics /
"The Routledge Handbook of Sport and Exercise Systems Genetics constitutes the most authoritative and comprehensive reference in this critical area of study, consolidating knowledge and providing a framework for interpreting future research findings. Taking an approach which covers single gene...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Abingdon, Oxon ; New York, NY :
Routledge,
2019.
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| Colección: | Routledge international handbooks.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Half Title; Title Page; Copyright Page; Table of contents; List of Figures; List of Tables; List of Contributors; Foreword; Preface; Introduction; References; Section 1 General systems genetics; 1 Why study the systems genetics of sport and exercise?; Introduction; Exercise systems genomics; Exercise presents a high stress; however, the body is able to survive by maintaining its homeostasis ... ; Exercise systems genetics versus inactivity systems genetics; Physical inactivity is a necessary reference group to show healthy exercise effects
- and turns ...
- A biased positive look to the futureA projection into where technology seems to be taking physical inactivity; Multiple, biased, concerned looks to the future; New technology is often based upon reducing physical activity; Inheritance of low voluntary running behavior; Does epigenetics play a role in type 2 diabetes and in physical inactivity?; Low voluntary running animal model to mimic increased human inactivity; The high economic costs of physical inactivity are contributing in their small way to the bankruptcy of our children's future cost of living
- What systems genetics could do for humansReferences; 2 Expansion of knowledge and advances in genetics for quantitative analyses; Introduction; The Human Genome Project; Advances in sequencing; Association studies; Noncoding sequences; Noncoding RNA and antisense sequences; MicroRNAs; Exosomes; Epigenetics; Summary; References; 3 human systems genetic modeling used in exercise; Introduction; Study of families; What are families?; Quantifying family data; Twin studies; Biology of twins and twinning; The classical twin model; Basic concepts of the twin model; The univariate twin model
- Multivariate twin modelsMZ discordant pairs to study causal associations; Adoption studies; Twin family designs; Genome-wide association studies; The future in the era of molecular genetics; Further reading; References; 4 The translation of systems genetics of exercise to everyday life; Introduction; Theoretical foundations of exercise interventions; Translating exercise genomics into practice; Using genetic information to enhance exercise adherence; Using genetic information to enhance exercise prescription and intervention
- Using genetic information to identify individuals at risk for exercise dropoutConclusion; References; Section 2 Systems genetics of physical activity; 5 Is physical activity regulated by genetics? Evidence from animal models; What is physical activity in an animal model?; Heritability; Genetic architecture; Genetic mapping; Fine-mapping approaches; Future directions; References; 6 Is physical activity regulated by genetics? Evidence from studies in humans; Introduction; Twin studies; Physical activity phenotypes; Meta-analyses; Results for total physical activity