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Bone Marrow Pathology

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Bain, Barbara J.
Otros Autores: Clark, David M., Wilkins, Bridget S.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newark : John Wiley & Sons, Incorporated, 2019.
Edición:5th ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro; Title Page; Copyright Page; Contents; Preface to the Fifth Edition; Acknowledgements; Abbreviations; Chapter One The normal bone marrow; The distribution of haemopoietic marrow; The organization of the bone marrow; Bone; Other connective tissue elements; Haemopoietic and other cells; Examination of the bone marrow; Bone marrow aspiration; Trephine biopsy of bone marrow; Relative advantages of aspiration and core biopsy; Other techniques; Cellularity; Haemopoietic and mesenchymal cells; Erythropoiesis; Granulopoiesis; Monocytopoiesis; Stromal dendritic cells
  • Megakaryopoiesis and thrombopoiesisMast cells; Osteoblasts and osteoclasts; Fat cells; Lymphopoiesis; Lymphocytes; Plasma cells; Storage and erythroblast iron; The cellular composition of bone marrow; Interpretation of bone marrow aspirates and trephine biopsies; Examination of bone marrow aspirate films; Reporting a bone marrow aspirate; Examination of trephine biopsy sections; Reporting trephine biopsy sections; Guidelines, integrated reporting and audit; Artefacts; References; Chapter Two Special Techniques Applicable to Bone Marrow Diagnosis; Cytochemical and histochemical stains
  • Cytochemical stains on bone marrow aspiratesHistochemical stains on trephine biopsy sections; Immunophenotyping; Immunophenotyping by immunofluorescence flow cytometry; Immunocytochemistry; Relative advantages of flow cytometry and immunocytochemistry; Antibodies for flow cytometry and immunocytochemistry; Immunohistochemistry; Cytogenetic analysis; Molecular genetic analysis; Fluorescence and other in situ hybridization techniques; Southern blot analysis; The polymerase chain reaction; Reverse transcriptase polymerase chain reaction; Modifications of PCR and RT-PCR techniques
  • Microarray analysisNext generation sequencing; Other molecular genetic techniques; The application of molecular genetic techniques in the investigation of leukaemia and lymphoma; Detecting clonal immunoglobulin and T-cell receptor gene rearrangements; Detection of leukaemia/lymphoma-associated fusion genes; Ultrastructural examination; Bone marrow culture for assessment of haemopoietic progenitor cell numbers; Short-term culture; Long-term culture; Bone marrow culture for microorganisms; References; Chapter Three Infection And Reactive Changes; Infection; Bacterial and rickettsial infection
  • Viral infectionFungal infections; Parasitic diseases; Bone marrow granulomas; Reactive lymphoid aggregates and polymorphous lymphoid hyperplasia; Plasmacytosis and cytological abnormalities in plasma cells; Mast cells; Histiocytosis; Haemophagocytic syndromes; Iron overload; HIV infection and the acquired immune deficiency syndrome; Bone marrow necrosis; Gelatinous transformation; Amyloid deposition; Bone marrow fibrosis; References; Chapter Four Acute myeloid leukaemia, mixed phenotype acute leukaemia, the myelodysplastic syndromes and histiocytic neoplasms; Acute myeloid leukaemia