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Immunology : an introductory textbook /

Immunology has emerged as a key component of the curricula of graduate and postgraduate courses in biotechnology, microbiology, biochemistry, bioinformatics, and other interdisciplinary fields of biology, including zoology, veterinary science, and medicine. As a basic introductory textbook on one of...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Sharma, Anil K., 1980- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : Pan Stanford Publishing, 2019.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Immunology :  |b an introductory textbook /  |c edited by Anil K. Sharma. 
264 1 |a Singapore :  |b Pan Stanford Publishing,  |c 2019. 
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504 |a Includes bibliographical references and index. 
505 0 |a Cover; Half Title; Title Page; Copyright Page; Table of Contents; Preface; 1: Introduction to lmmunology; 1.1 Historical Attributes; 1.2 lmmunological Responses and Effectors; 1.2.1 lnnate and Adaptive lmmunity; 1.2.1.1 lnnate immunity; 1.2.1.2 Adaptive immunity; 1.3 Summary; 2: lmmunity; 2.1 Basic Concept of lmmunity; 2.2 Historical Background of Immune Responses; 2.3 Cell-Mediated Immune Responses; 2.4 Processing of Endogenous Antigens: Cytosolic Pathway; 2.5 Processing of Endogenous Antigens: Endocytic Pathway; 2.6 Humoral Immunity; 2.7 Activation of B-Cells 
505 8 |a 2.8 Humoral Response to T-Dependent Antigens2.9 Humoral Response to T-lndependent Antigens; 3: Proteins of the Immune System; 3.1 Antimicrobial Peptide; 3.2 Pattern Recognition Receptor; 3.3 Toll-Like Receptors; 3.4 NOD Protein; 3.5 Acute Phase Proteins; 3.6 Interferon; 3.7 Complement System; 3.7.1 Function of Complement System; 3.7.2 Complement Nomenclature; 3.8 Activation of Complement Pathways; 3.9 Classical Pathway of the Complement System; 3.10 Lectin Pathway; 3.11 Alternative Pathway; 3.12 Small Fragments of the Complement Protein Initiates Local Inflammatory Response 
505 8 |a 3.13 Membrane Attack Complex (MAC) or Lytic Pathway3.14 Regulation of Complement Protein; 3.15 Summary; 4: Major Histocompatibility Complex (MHC): Recent Trends and Relevance from lmmunological Perspective; 4.1 Introduction; 4.2 Nomenclature of HLA Antigens; 4.3 Frequency of Different HLA Alleles; 4.4 Molecular and Genetics Basis of MHC Polymorphisms; 4.4.1 Inheritance; 4.4.2 Expression; 4.5 MHC Molecules: Structure and Genetics; 4.5.1 MHC Class I vs. MHC Class Il; 4.5.1.1 MHC Class I; 4.5.1.2 MHC Class Il; 4.6 Role of MHC in Immune Response; 4.6.1 The Mixed Lymphocyte Reaction 
505 8 |a 4.6.2 Antigen Processing and Presentation4.6.3 Sorne Points about MHC Class I and Class Il /TCR; 4.7 Antigen Processing and Presentation; 4.8 Langerhans Cells as APC; 4.9 Antigen Processing and Presentation by Class Il (Exogenous/Endocytic) Pathway; 4.10 Antigen Processing and Presentation by Class I (Endogenous/Cytosolic) Pathway; 4.11 Significance of MHC-Peptide Presentation; 4.12 Clonal Selection of T-cells; 4.13 Generation of Cytotoxic T-Cells; 4.14 Immune Response Genes; 4.15 Complement Factor Genes; 4.16 Nonimmunologic Functions of MHC Genes 
505 8 |a 4.17 Disease and the Major Histocompatibility Complex5: Immune System of the Brain; 5.1 Introduction; 5.2 Microglia; 5.3 Astrocytes; 5.4 Toll-Like Receptors; 5.5 Pro-lnflammatory Cytokines; 5.6 Summary; 6: An Overview of lmmunodeficiency Disorders; 6.1 Introduction; 6.2 Primary lmmunodeficiency Diseases; 6.3 Classification of Primary lmmunodeficiency; 6.3.1 Severe Combined lmmunodeficiency; 6.3.1.1 X-linked recessive severe combined immunodeficiency; 6.3.1.2 Adenosine deaminase deficiency; 6.3.2 Well-Defined Syndromes with lmmunodeficiency 
520 |a Immunology has emerged as a key component of the curricula of graduate and postgraduate courses in biotechnology, microbiology, biochemistry, bioinformatics, and other interdisciplinary fields of biology, including zoology, veterinary science, and medicine. As a basic introductory textbook on one of the fastest-moving and most challenging areas of immunological science, this book contains the most recent information about immunologic mechanisms and their importance, along with various molecular techniques employed in immunology. The short and concise text helps make the structures, processes, and interactions of the immune system easily comprehensible. The book includes chapters on immunoinformatics as well as the immune system of the brain, rarely found in any of the immunology books published so far. Many diverse and interesting aspects of the advances in immunology have also been covered, including tumor immunology and immunodeficiency disorders. The easy-to-understand concepts presented in the textbook make it an ideal companion for learners preparing for competitive and other examinations. Undergraduate, postgraduate, and PhD students, people from the industry and academia, and research scholars will immensely benefit from it. 
545 0 |a Anil K. Sharma is full professor and head of the Department of Biotechnology at Maharishi Markandeshwar (Deemed to be University), India, since 2010. From 2003 to 2010, he was a senior research scientist and a postdoctoral research fellow (molecular biology) at the Department of Microbiology and Immunology of the University of Illinois College of Medicine, Chicago, USA. He gained exposure to industrial R & D when he worked for Ranbaxy Research Laboratories, a multinational pharma major, as a research scientist from 2001 to 2003. Prof. Sharma has published 6 books and more than 100 articles in peer-reviewed journals with h-Index of 16 (i10 score of 23), and the cumulative impact factor of his publications is more than 130.0, with more than 1000 citations. He has been felicitated with many prestigious awards and accolades, including the Eminent Scientist Award (2017), Achiever Award of the Society for the Advancement of Human and Nature (2016), and Bharat Excellence Award (2013). He has been the editor or an editorial board member for several journals of international repute. His research interests range from the etiology of breast cancer, immunoregulation in prokaryotes and eukaryotes, drug resistance, and nanomedicines to the development of microbial strains for the remediation of heavy metals and pesticides. 
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700 1 |a Sharma, Anil K.,  |d 1980-  |e editor. 
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