Handbook of statistical genomics /
This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd...
Clasificación: | Libro Electrónico |
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Otros Autores: | , , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Hoboken, NJ :
Wiley,
2019.
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Edición: | Fourth edition. |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Volume 1 List of Contributors xxiii Editors' Preface to the Fourth Edition xxvii Glossary xxix Abbreviations and Acronyms xxxix 1 Statistical Modeling and Inference in Genetics 1; Daniel Wegmann and Christoph Leuenberger 2 Linkage Disequilibrium, Recombination and Haplotype Structure 51; Gil McVean and Jerome Kelleher 3 Haplotype Estimation and Genotype Imputation 87; Jonathan Marchini 4 Mathematical Models in Population Genetics 115; Nick Barton and Alison Etheridge 5 Coalescent Theory 145; Magnus Nordborg 6 Phylogeny Estimation Using Likelihood-Based Methods 177; John P. Huelsenbeck 7 The Multispecies Coalescent 219; Laura Kubatko 8 Population Structure, Demography and Recent Admixture 247; G.
- Hellenthal 9 Statistical Methods to Detect Archaic Admixture and Identify Introgressed Sequences 275; Liming Li and Joshua M. Akey 10 Population Genomic Analyses of DNA from Ancient Remains 295; Torsten Gunther and Mattias Jakobsson 11 Sequence Covariation Analysis in Biological Polymers 325; William R. Taylor, Shaun Kandathil, and David T. Jones 12 Probabilistic Models for the Study of Protein Evolution 347; Umberto Perron, Iain H. Moal, Jeffrey L. Thorne, and Nick Goldman 13 Adaptive Molecular Evolution 369; Ziheng Yang 14 Detecting Natural Selection 397; Aaron J. Stern and Rasmus Nielsen 15 Evolutionary Quantitative Genetics 421; Bruce Walsh and Michael B.
- Morrissey 16 Conservation Genetics 457; Mark Beaumont and Jinliang Wang 17 Statistical Methods for Plant Breeding 501; Ian Mackay, Hans-Peter Piepho, and Antonio Augusto Franco Garcia 18 Forensic Genetics 531; B.S.Weir Volume 2 19 Ethical Issues in Statistical Genetics 551; Susan E. Wallace and Richard Ashcroft 20 Descent-Based Gene Mapping in Pedigrees and Populations 573; E.A. Thompson 21 Genome-Wide Association Studies 597; Andrew P. Morris and Lon R. Cardon 22 Replication and Meta-analysis of Genome-Wide Association Studies 631; Frank Dudbridge and Paul Newcombe 23 Inferring Causal Relationships between Risk Factors and Outcomes Using Genetic Variation 651; Stephen Burgess, Christopher N.
- Foley, and Verena Zuber 24 Improving Genetic Association Analysis through Integration of Functional Annotations of the Human Genome 679; Qiongshi Lu and Hongyu Zhao 25 Inferring Causal Associations between Genes and Disease via the Mapping of Expression Quantitative Trait Loci 697; Solveig K. Sieberts and Eric E. Schadt 26 Statistical Methods for Single-Cell RNA-Sequencing 735; Tallulah S. Andrews, Vladimir Yu. Kiselev, and Martin Hemberg 27 Variant Interpretation and Genomic Medicine 761; K. Carss, D. Goldstein, V. Aggarwal, and S. Petrovski 28 Prediction of Phenotype from DNA Variants 799; M.E. Goddard, T.H.E. Meuwissen, and H.D.
- Daetwyler 29 Disease Risk Models 815; Allison Meisner and Nilanjan Chatterjee 30 Bayesian Methods for Gene Expression Analysis 843; Alex Lewin, Leonardo Bottolo, and Sylvia Richardson 31 Modelling Gene Expression Dynamics with Gaussian Process Inference 879; Magnus Rattray, Jing Yang, Sumon Ahmed, and Alexis Boukouvalas 32 Modelling Non-homogeneous Dynamic Bayesian Networks with Piecewise Linear Regression Models 899; Marco Grzegorczyk and Dirk Husmeier 33 DNA Methylation 933; Kasper D. Hansen, Kimberly D. Siegmund, and Shili Lin 34 Statistical Methods in Metabolomics 949; Timothy M.D. Ebbels, Maria De Iorio, and David A. Stephens 35 Statistical and Computational Methods in Microbiome and Metagenomics 977; Hongzhe Li 36 Bacterial Population Genomics 997; Jukka Corander, Nicholas J. Croucher, Simon R. Harris, John A.