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Color Atlas of Clinical Hematology : Molecular and Cellular Basis of Disease.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Hoffbrand, Victor
Otros Autores: Vyas, Paresh, Campo, Elias, Haferlach, Torsten, Gomez, Keith
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newark : John Wiley & Sons, Incorporated, 2018.
Edición:5th ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro; TITLE PAGE; COPYRIGHT PAGE; CONTENTS; PREFACE; CHAPTER 1 MOLECULAR BIOLOGY OF THE CELL; COMPARTMENTALIZATION OF THE CELL; THE NUCLEUS; GENE TRANSCRIPTION AND MESSENGER RNA TRANSLATION: THE PRODUCTION AND JOURNEY OF mRNA; DNA MUTATIONS CAN ALTER PROTEIN SYNTHESIS BY A NUMBER OF MECHANISMS; TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION; CIS-ELEMENTS AND TRANSCRIPTION FACTORS; CHROMATIN AND EPIGENETIC CONTROL OF GENE EXPRESSION; TRANSCRIPTION FACTORS, CONTROL OF GENE EXPRESSION, AND LINEAGE COMMITMENT; MICRO-RNAs; REGULATORY NONCODING RNAs; DNA REPLICATION AND TELOMERES
  • MUTATIONS AND HOW THEY RESULT IN DISEASECELL CYCLE; APOPTOSIS; ORGANELLES IN CELLS; MITOCHONDRIA; LINK BETWEEN METABOLISM AND GENE EXPRESSION; REMOVAL OF CIRCULATING AND CELLULAR DEBRIS BY LYSOSOMES; PROTEIN UBIQUITINATION; CHAPTER 2 HEMATOPOIESIS; SITES OF HEMATOPOIESIS; ROAD MAPS OF HEMATOPOIESIS; CELLULAR PATHWAYS AS HSCs DIFFERENTIATE INTO TERMINALLY MATURE CELLS; TRANSCRIPTIONAL CONTROL OF HEMATOPOIESIS; THE HEMATOPOIETIC NICHE; CHAPTER 3 GROWTH FACTOR SIGNALING; SIGNALING AT DIFFERENT STAGES OF HEMATOPOIESIS; CYTOKINE RECEPTORS; SIGNALING PATHWAYS DOWNSTREAM OF RECEPTORS; WNT PATHWAY
  • CYTOKINE SIGNALING PATHWAYSTHE RAS/MAP KINASE PATHWAY; PHOSPHATIDYLINOSITOL 3-KINASE PATHWAY; JAK-STAT PATHWAY; MUTATIONS IN SIGNALING COMPONENTS LEADING TO CLONAL HEMATOLOGIC DISORDERS; CHAPTER 4 ERYTHROPOIESIS AND EXAMINATION OF THE PERIPHERAL BLOOD AND BONE MARROW; ERYTHROPOIESIS; EXAMINATION OF PERIPHERAL BLOOD AND THE BONE MARROW; ERYTHROID CELLS IN THE BONE MARROW AND PERIPHERAL BLOOD; CHAPTER 5 HYPOCHROMIC ANEMIAS; IRON METABOLISM; IRON ABSORPTION; HEPCIDIN; IRON HOMEOSTASIS; IRON-DEFICIENCY ANEMIA; BLOOD AND BONE MARROW APPEARANCES; CAUSES OF IRON DEFICIENCY
  • IRON-REFRACTORY IRON-DEFICIENCY ANEMIA (IRIDA)SIDEROBLASTIC ANEMIA; CONGENITAL SIDEROBLASTIC ANEMIA; ALCOHOL; LEAD POISONING; DIFFERENTIAL DIAGNOSIS OF HYPOCHROMIC MICROCYTIC ANEMIAS; CHAPTER 6 THE PORPHYRIAS AND IRON OVERLOAD; CONGENITAL ERYTHROPOIETIC PORPHYRIA; CONGENITAL ERYTHROPOIETIC PROTOPORPHYRIA; IRON OVERLOAD; GENETIC HEMOCHROMATOSIS; RARE CAUSES OF IRON OVERLOAD; HEREDITARY HYPERFERRITINEMIA WITH AUTOSOMAL DOMINANT CONGENITAL CATARACT SYNDROME; CHAPTER 7 MEGALOBLASTIC ANEMIAS; CLINICAL FEATURES; BLOOD COUNT AND BLOOD FILM APPEARANCES; BONE MARROW APPEARANCES
  • CAUSES OF MEGALOBLASTIC ANEMIAVITAMIN B12 DEFICIENCY; FOLATE DEFICIENCY; ABNORMALITIES OF VITAMIN B12 OR FOLATE METABOLISM; OTHER CAUSES; CHAPTER 8 HEMOLYTIC ANEMIAS; HEREDITARY HEMOLYTIC ANEMIA; NORMAL RED CELL MEMBRANE; RED CELL BLOOD GROUP ANTIGENS; HEREDITARY SPHEROCYTOSIS; HEREDITARY ELLIPTOCYTOSIS; NORMAL RED CELL METABOLISM; HEMOLYTIC ANEMIAS ASSOCIATED WITH INHERITED DEFECTS OF ENZYMES; ACQUIRED HEMOLYTIC ANEMIA; AUTOIMMUNE HEMOLYTIC ANEMIAS; EVANS SYNDROME; DRUG-INDUCED IMMUNE HEMOLYTIC ANEMIA; ISOIMMUNE HEMOLYTIC ANEMIA; RED CELL FRAGMENTATION SYNDROMES; SECONDARY HEMOLYTIC ANEMIAS