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20240329122006.0 |
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181117s2018 cau o 000 0 eng d |
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|a EBLCP
|b eng
|e pn
|c EBLCP
|d OCLCQ
|d OCLCL
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| 020 |
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|a 9780128124345
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| 020 |
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|a 0128124342
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|a AU@
|b 000068485477
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|a (OCoLC)1066179102
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|a 572.865
|q OCoLC
|2 23/eng/20231120
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| 049 |
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|a UAMI
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| 100 |
1 |
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|a McCullough, Shaun D.
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| 245 |
1 |
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|a Epigenetic Toxicology :
|b Core Principles and Applications.
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| 260 |
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|a San Diego :
|b Elsevier Science & Technology,
|c 2018.
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| 300 |
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|a 1 online resource (430 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a Front Cover; Toxicoepigenetics: Core Principles and Applications; Copyright; Contents; Contributors; Editors' Biography; Introduction to the Role of the Epigenome in Health and Disease; Section 1: Histone Modifications and Chromatin Structure; Chapter 1-1: Role of Histone Acetylation and Acetyltransferases in Gene Regulation; Introduction; History and Overview; Nucleosome Assembly; Chromatin Folding; Gene Expression; DNA Damage Repair; Toxicoepigenetic Relevance; Histone Acetyltransferases; Families and Structures; Regulation of HATs; Transcriptional Activation; HAT Complexes.
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| 505 |
8 |
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|a SAGA Transcription Regulatory ComplexNuA4 Transcription Regulatory Complex; Elongator Complex; Chromatin Remodeling Complexes; Global Histone Acetylation; Role of Histone Acetyltransferases in Gene Activation; Recruitment of Transcriptional Machinery; Active Genes; Inducible/Repressed Genes; Environmental Exposure; Histone Deacetylases; Families; Catalytic Mechanisms and Structures; Regulation of HDAC Activity; Role of HDACs at Active Genes; Deacetylation and Gene Repression; HDAC Complexes; Conclusion and Perspectives; References.
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| 505 |
8 |
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|a Chapter 1-2: The Role of Histone Methylation and Methyltransferases in Gene RegulationIntroduction; Site Specificity of Histone Methylation; Lysine Methylation; H2BK5 Methylation; H3K4 Methylation; H3K9 Methylation; H3K27 Methylation; H3K36 Methylation; H3K79 Methylation; H4K20 Methylation; H4K5 Methylation; Arginine Methylation; Glutamine Methylation; Regulation of Histone Methylation; Posttranscriptional Modifications; Noncoding RNAs; Regulation of Xenobiotic Biotransformation-Related Genes by Histone Methylation; Histone Methylation and Human Diseases; Histone Methylation and Cancer.
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| 505 |
8 |
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|a Histone Methylation and Neurological DisordersHistone Methylation and Other Diseases; Histone Methylation and the Toxicity of Chemicals; Heavy Metals; Endocrine Disruptors (EDCs); Human Genotoxic Chemical Carcinogens From Occupational and Environmental Exposure; Other Xenobiotics; Conclusion; References; Chapter 1-3: Chromatin Accessibility as a Strategy to Detect Changes Associated With Development, Disease, and Exposure a ... ; Chromatin Accessibility as a Marker of Cell Lineage; Methods for Determining Chromatin Architecture and Accessibility; DNase I Hypersensitivity Assays.
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| 505 |
8 |
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|a Micrococcal Nuclease AssaysFormaldehyde Assisted Isolation of Regulatory Elements (FAIRE); Assay for Transposase-Accessible Chromatin (ATAC); Nucleosome Occupancy and Methylome Sequencing (NOMe-seq); Single Cell Assays for Determining Chromatin Accessibility in Heterogenous Cell Populations; Chromatin Accessibility and Disease; Understanding How Environmental Factors Influence Chromatin Accessibility; Chromatin Accessibility and Cancer; Chromatin Signature as a Diagnostic and Therapeutic Target in Cancer; References; Further Reading.
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| 500 |
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|a Chapter 1-4: Implications for Chromatin Biology in Toxicology.
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| 590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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| 700 |
1 |
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|a Dolinoy, Dana.
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| 758 |
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|i has work:
|a Epigenetic Toxicology (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCY3Y8XJQpRFhKfhvxxt83P
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
| 776 |
0 |
8 |
|i Print version:
|a McCullough, Shaun D.
|t Epigenetic Toxicology : Core Principles and Applications.
|d San Diego : Elsevier Science & Technology, ©2018
|z 9780128124338
|
| 856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5579889
|z Texto completo
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| 938 |
|
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|a ProQuest Ebook Central
|b EBLB
|n EBL5579889
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| 994 |
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|a 92
|b IZTAP
|
