Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases /
"Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowle...
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Hoboken, NJ :
Wiley,
2019.
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Temas: | |
Acceso en línea: | Texto completo Texto completo |
MARC
LEADER | 00000cam a2200000 i 4500 | ||
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001 | EBOOKCENTRAL_on1061865433 | ||
003 | OCoLC | ||
005 | 20240329122006.0 | ||
006 | m o d | ||
007 | cr ||||||||||| | ||
008 | 181105s2019 nju ob 001 0 eng | ||
010 | |a 2018053075 | ||
040 | |a DLC |b eng |e rda |c DLC |d DG1 |d YDX |d N$T |d EBLCP |d OCLCF |d UAB |d CHVBK |d MERER |d DLC |d OCLCO |d OCLCA |d OCLCO |d K6U |d OCL |d OCLCQ |d OCLCO | ||
019 | |a 1086209622 | ||
020 | |a 9781119289210 |q (Adobe PDF) | ||
020 | |a 1119289211 | ||
020 | |a 9781119289227 |q (ePub) | ||
020 | |a 111928922X | ||
020 | |z 9781119289197 |q (hardback) | ||
020 | |a 9781119289234 |q (electronic bk. ; |q oBook) | ||
020 | |a 1119289238 |q (electronic bk. ; |q oBook) | ||
029 | 1 | |a CHVBK |b 559026838 | |
029 | 1 | |a CHNEW |b 001039220 | |
029 | 1 | |a AU@ |b 000065193807 | |
035 | |a (OCoLC)1061865433 |z (OCoLC)1086209622 | ||
042 | |a pcc | ||
050 | 1 | 0 | |a RC600 |
060 | 1 | 0 | |a WD 305 |
072 | 7 | |a HEA |x 039000 |2 bisacsh | |
072 | 7 | |a MED |x 014000 |2 bisacsh | |
072 | 7 | |a MED |x 022000 |2 bisacsh | |
072 | 7 | |a MED |x 112000 |2 bisacsh | |
072 | 7 | |a MED |x 045000 |2 bisacsh | |
082 | 0 | 0 | |a 616.97/806 |2 23 |
049 | |a UAMI | ||
245 | 0 | 0 | |a Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases / |c edited by Honghui Zhou, Diane R. Mould. |
264 | 1 | |a Hoboken, NJ : |b Wiley, |c 2019. | |
300 | |a 1 online resource | ||
336 | |a text |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
500 | |a "John Wiley & Sons Inc."--tp verso. | ||
504 | |a Includes bibliographical references and index. | ||
520 | |a "Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowledge of using PK/PD modeling tools to address a variety of problems in development of therapeutic proteins. Reviews and discusses biomarkers, systems pharmacology, PBPK modeling, and target-mediated modeling, as translational tools. Helps readers understand disease progression and identify of mechanisms-based biomarkers with clinical relevance"--Provided by publisher. | ||
588 | |a Description based on print version record and CIP data provided by publisher. | ||
505 | 0 | |a Disease Interception in Autoimmune Diseases: From a Conceptual Framework to Practical Implementation / Anish Suri -- The Role of Biomarkers in Treatment Algorithms for Ulcerative Colitis (UC) / Reena Khanna, Brian G Feagan -- Mechanism and Physiologically Based PK/PD Model in Assisting Translation from Preclinical to Clinical: Understanding PK/PD of Therapeutic Proteins at Site-of-Action / Xi Chen, Weirong Wang -- Application of Minimal Anticipated Biological Effect Level (MABEL) in Human Starting Dose Selection for Immunomodulatory Protein Therapeutics -- Principles and Case Studies / Haiqing Wang, Zheng Yang, Rong Shi -- Model-Based Meta-Analysis Use in the Development of Therapeutic Proteins / Timothy J Taylor, Bill Frame, Angela D Taylor -- Utility of Joint Population Exposure-Response Modeling Approach to Assess Multiple Continuous and Categorical Endpoints in Immunology Drug Development / Chuanpu Hu, Honghui Zhou -- Modeling Approaches to Characterize Target-Mediated Pharmacokinetics and Pharmacodynamics for Therapeutic Proteins / Leonid Gibiansky, Ekaterina Gibiansky -- Tutorial: Numerical (NONMEM) Implementation of the Target-Mediated Drug Disposition Model / Leonid Gibiansky, Ekaterina Gibiansky -- Translational Considerations in Developing Bispecific Antibodies: What Can We Learn from Quantitative Pharmacology? / Pradeep B Lukka, Santosh Wagh, Bernd Meibohm -- Application of Pharmacometrics and Systems Pharmacology to Current and Emerging Biologics in Inflammatory Bowel Diseases / Sihem Ait-Oudhia, Yi Ting (Kayla) Lien, Sumit Basu, Lawrence Lesko, Stephan Schmidt -- Pharmacokinetics-Based Dosing for Therapeutic Monoclonal Antibodies in Inflammatory Bowel Disease / Niels Vande Casteele, William J Sandborn -- Pharmacokinetics-Based Dosing Strategies for Therapeutic Proteins in Inflammatory Bowel Disease / Diane R Mould, Richard N Upton, Jessica Wojciechowski -- Quantitative Pharmacology Approach to Select Optimal Dose and Study the Important Factors in Determining Disposition of Therapeutic Monoclonal Antibody in Pediatric Subjects -- Some Considerations / Deni Hardiansyah, Chee M Ng -- Quantitative Pharmacology Assessment Strategy Therapeutic Proteins in Pediatric Subjects -- Challenges and Opportunities / Jeremiah D Momper, Andrew Mulberg, Nitin Mehrotra, Dan Turner, William Faubion, Laurie Conklin, Karim Azer, Marla C Dubinsky -- Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins for Plaque Psoriasis -- Guselkumab / Zhenling Yao, Yaowei Zhu, Chuanpu Hu, Yang Chen, Shu Li, Bruce Randazzo, Zhenhua Xu, Amarnath Sharma, Honghui Zhou -- Vedolizumab-A Case Example of Using Quantitative Pharmacology in Developing Therapeutic Biologics in Inflammatory Bowel Disease / Maria Rosario, Nathanael L Dirks, Diane R Mould, Catherine Scholz, Timothy Wyant, Asit Parikh, Irving Fox -- Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins in Systemic Lupus Erythematosus -- Belimumab / Herbert Struemper -- Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins in Multiple Sclerosis -- Peginterferon Beta-1a, Daclizumab Beta, Natalizumab / Xiao Hu, Yaming Hang, Lei Diao, Kumar K Muralidharan, Ivan Nestorov -- Index -- Supplemental Images. | |
590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
590 | |a O'Reilly |b O'Reilly Online Learning: Academic/Public Library Edition | ||
650 | 0 | |a Immunologic diseases |x Treatment. | |
650 | 0 | |a Pharmacology. | |
650 | 0 | |a Mathematical models. | |
650 | 1 | 2 | |a Autoimmune Diseases |x drug therapy |
650 | 1 | 2 | |a Proteins |x therapeutic use |
650 | 2 | 2 | |a Proteins |x pharmacokinetics |
650 | 2 | 2 | |a Protein Engineering |x methods |
650 | 2 | 2 | |a Models, Theoretical |
650 | 2 | |a Pharmacology | |
650 | 6 | |a Maladies immunologiques |x Traitement. | |
650 | 6 | |a Pharmacologie. | |
650 | 6 | |a Modèles mathématiques. | |
650 | 7 | |a pharmacology. |2 aat | |
650 | 7 | |a mathematical models. |2 aat | |
650 | 7 | |a HEALTH & FITNESS |x Diseases |x General. |2 bisacsh | |
650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
650 | 7 | |a MEDICAL |x Diseases. |2 bisacsh | |
650 | 7 | |a MEDICAL |x Evidence-Based Medicine. |2 bisacsh | |
650 | 7 | |a MEDICAL |x Internal Medicine. |2 bisacsh | |
650 | 7 | |a Mathematical models |2 fast | |
650 | 7 | |a Immunologic diseases |x Treatment |2 fast | |
650 | 7 | |a Pharmacology |2 fast | |
700 | 1 | |a Zhou, Honghui, |e editor. | |
700 | 1 | |a Mould, Diane R. |q (Diane Renee), |d 1960- |e editor. | |
776 | 0 | 8 | |i Print version: |t Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases |b First edition. |d Hoboken, NJ : Wiley, [2019] |z 9781119289197 |w (DLC) 2018051418 |
856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5709855 |z Texto completo |
856 | 4 | 0 | |u https://learning.oreilly.com/library/view/~/9781119289197/?ar |z Texto completo |
938 | |a YBP Library Services |b YANK |n 16080648 | ||
938 | |a YBP Library Services |b YANK |n 16055307 | ||
938 | |a EBSCOhost |b EBSC |n 2030089 | ||
938 | |a ProQuest Ebook Central |b EBLB |n EBL5709855 | ||
994 | |a 92 |b IZTAP |