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|b eng
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|a 9780128136980
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|a 0128136987
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|a (OCoLC)1061127152
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|a RA1199.4.A46 .H578 2019
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|a 615.907
|2 23
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|a UAMI
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|a Michael, Balls.
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|a The History of Alternative Test Methods in Toxicology.
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|a San Diego :
|b Elsevier Science & Technology,
|c 2018.
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|a 1 online resource (384 pages)
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a History of Toxicology and Environmental Health Ser.
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|a Print version record.
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|a Front Cover; The History of Alternative Test Methods in Toxicology; The History of Alternative Test Methods in Toxicology; Copyright; Contents; Contributors; Biographical Notes; CO-EDITORS; CO-AUTHORS; Preface to the Series; Preface for The History of Alternative Test Methods in Toxicology; 1 -- Setting the Scene; 1.1 -- The Introduction and Influence of the Concept of Humane Experimental Technique; 1. INHUMANITY AND THE THREE RS CONCEPT; 2. PROGRESS FOLLOWING THE PUBLICATION OF THE PRINCIPLES; 3. ALTERNATIVES; 4. PROGRESS IN THE 1980S; 5. INTO THE 1990S; REFERENCES.
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|a 1.2 -- Types of Toxicity and Applications of Toxicity Testing1. THE NEED FOR TESTING; 2. TYPES OF TOXICITY TEST; 3. APPLICATIONS OF TOXICITY TESTING; 4. RISK MANAGEMENT; 5. THE REPLACEMENT OF ANIMAL TESTS; 6. CONCLUSIONS; REFERENCES; 1.3 -- The Key Technologies; 1. INTRODUCTION; 2. TECHNOLOGY DRIVERS; 2.1 Tissue Culture Systems; 2.2 Reporter Gene Assays and Biosensors; 2.3 Miniaturised and Large-Scale Culture Systems; 2.4 Toxicogenomics and Proteomics; 2.5 Other Enabling Technologies; 3. DISCUSSION AND CONCLUSIONS; REFERENCES; 2 -- Contributions From Countries, Regions and Organisations.
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|a 2.1 -- Alternative Methods in Toxicity Testing in the UK1. EARLY DAYS; 2. THE FUND FOR THE REPLACEMENT OF ANIMALS IN MEDICAL EXPERIMENTS; 3. THE NATIONAL CENTRE FOR THE THREE RS; 4. OTHER ORGANISATIONS; REFERENCES; 2.2 -- Contributions From the German-Speaking Countries; 1. INTRODUCTION; 2. CONTRIBUTIONS FROM SWITZERLAND; 2.1 The Foundation Research 3R; 2.2 The Swiss Institute for Alternatives to Animal Testing; 2.3 The Fondation Egon Naef Pour la Recherche In Vitro; 2.4 Swiss Governmental Agency Support for the Three Rs Concept; 3. CONTRIBUTIONS FROM GERMANY.
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|a 3.1 Zentralstelle zur Erfassung und Bewertung von Ersatz- und Ergaenzungsmethoden zum Tierversuch (ZEBET)3.2 Reducing Animal Numbers in Regulatory Toxicity Testing; 3.3 The Regulatory Acceptance of In Vitro Toxicity Tests Successfully Validated at ZEBET; 3.4 The Funding of Research on In Vitro Toxicity Testing in Germany; 3.5 ZEBET's Wider Activities; 4. CONTRIBUTIONS FROM AUSTRIA; 5. CONCLUSIONS; REFERENCES; 2.3 -- Contributions to Alternatives From Italy and Spain; 1. ACTIVITIES IN ITALY RELATED TO ALTERNATIVE METHODS; 1.1 The Italian Association for In Vitro Toxicology.
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|a 1.2 The Italian National Platform for Alternative Methods1.3 The Italian National Reference Centre; 1.4 The Three Rs Declaration of Bologna; 2. ACTIVITIES IN SPAIN RELATED TO IN VITRO PHARMACOTOXICOLOGY; 2.1 The ICLAS/CSIC Working Group on Complementary Methods; 2.2 The Spanish Working Group on Alternative Methods; 2.3 The 3ERRES Mailing List on Alternatives; 2.4 Spanish Scientific Productivity Related to In Vivo and In Vitro Alternative Methods; 2.5 The Inventory of the Spanish Institutions and Scientists Involved in Alternatives to the Use of Laboratory Animals.
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500 |
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|a 2.6 The Spanish Network for the Development of Alternative Methods.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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0 |
|a Alternative toxicity testing.
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650 |
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0 |
|a Toxicology
|x Animal models
|x Moral and ethical aspects.
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650 |
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2 |
|a Animal Testing Alternatives
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650 |
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|a Expérimentation animale
|x Alternative.
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650 |
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|a Toxicologie
|x Modèles animaux
|x Aspect moral.
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650 |
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|a Alternative toxicity testing
|2 fast
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700 |
1 |
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|a Combes, Robert.
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700 |
1 |
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|a Worth, Andrew.
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758 |
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|i has work:
|a The history of alternative test methods in toxicology (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCFBYCj7RdMXgDRVVGyWVqP
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
8 |
|i Print version:
|a Michael, Balls.
|t History of Alternative Test Methods in Toxicology.
|d San Diego : Elsevier Science & Technology, ©2018
|z 9780128136973
|
830 |
|
0 |
|a History of Toxicology and Environmental Health Ser.
|
856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5561525
|z Texto completo
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938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL5561525
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994 |
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|a 92
|b IZTAP
|