Cargando…

The History of Alternative Test Methods in Toxicology.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Michael, Balls
Otros Autores: Combes, Robert, Worth, Andrew
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Elsevier Science & Technology, 2018.
Colección:History of Toxicology and Environmental Health Ser.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000Mu 4500
001 EBOOKCENTRAL_on1061127152
003 OCoLC
005 20240329122006.0
006 m o d
007 cr |n|---|||||
008 181103s2018 cau o 000 0 eng d
040 |a EBLCP  |b eng  |e pn  |c EBLCP  |d OCLCQ  |d AU@  |d OCLCF  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCL 
020 |a 9780128136980 
020 |a 0128136987 
035 |a (OCoLC)1061127152 
050 4 |a RA1199.4.A46 .H578 2019 
082 0 4 |a 615.907  |2 23 
049 |a UAMI 
100 1 |a Michael, Balls. 
245 1 4 |a The History of Alternative Test Methods in Toxicology. 
260 |a San Diego :  |b Elsevier Science & Technology,  |c 2018. 
300 |a 1 online resource (384 pages) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a History of Toxicology and Environmental Health Ser. 
588 0 |a Print version record. 
505 0 |a Front Cover; The History of Alternative Test Methods in Toxicology; The History of Alternative Test Methods in Toxicology; Copyright; Contents; Contributors; Biographical Notes; CO-EDITORS; CO-AUTHORS; Preface to the Series; Preface for The History of Alternative Test Methods in Toxicology; 1 -- Setting the Scene; 1.1 -- The Introduction and Influence of the Concept of Humane Experimental Technique; 1. INHUMANITY AND THE THREE RS CONCEPT; 2. PROGRESS FOLLOWING THE PUBLICATION OF THE PRINCIPLES; 3. ALTERNATIVES; 4. PROGRESS IN THE 1980S; 5. INTO THE 1990S; REFERENCES. 
505 8 |a 1.2 -- Types of Toxicity and Applications of Toxicity Testing1. THE NEED FOR TESTING; 2. TYPES OF TOXICITY TEST; 3. APPLICATIONS OF TOXICITY TESTING; 4. RISK MANAGEMENT; 5. THE REPLACEMENT OF ANIMAL TESTS; 6. CONCLUSIONS; REFERENCES; 1.3 -- The Key Technologies; 1. INTRODUCTION; 2. TECHNOLOGY DRIVERS; 2.1 Tissue Culture Systems; 2.2 Reporter Gene Assays and Biosensors; 2.3 Miniaturised and Large-Scale Culture Systems; 2.4 Toxicogenomics and Proteomics; 2.5 Other Enabling Technologies; 3. DISCUSSION AND CONCLUSIONS; REFERENCES; 2 -- Contributions From Countries, Regions and Organisations. 
505 8 |a 2.1 -- Alternative Methods in Toxicity Testing in the UK1. EARLY DAYS; 2. THE FUND FOR THE REPLACEMENT OF ANIMALS IN MEDICAL EXPERIMENTS; 3. THE NATIONAL CENTRE FOR THE THREE RS; 4. OTHER ORGANISATIONS; REFERENCES; 2.2 -- Contributions From the German-Speaking Countries; 1. INTRODUCTION; 2. CONTRIBUTIONS FROM SWITZERLAND; 2.1 The Foundation Research 3R; 2.2 The Swiss Institute for Alternatives to Animal Testing; 2.3 The Fondation Egon Naef Pour la Recherche In Vitro; 2.4 Swiss Governmental Agency Support for the Three Rs Concept; 3. CONTRIBUTIONS FROM GERMANY. 
505 8 |a 3.1 Zentralstelle zur Erfassung und Bewertung von Ersatz- und Ergaenzungsmethoden zum Tierversuch (ZEBET)3.2 Reducing Animal Numbers in Regulatory Toxicity Testing; 3.3 The Regulatory Acceptance of In Vitro Toxicity Tests Successfully Validated at ZEBET; 3.4 The Funding of Research on In Vitro Toxicity Testing in Germany; 3.5 ZEBET's Wider Activities; 4. CONTRIBUTIONS FROM AUSTRIA; 5. CONCLUSIONS; REFERENCES; 2.3 -- Contributions to Alternatives From Italy and Spain; 1. ACTIVITIES IN ITALY RELATED TO ALTERNATIVE METHODS; 1.1 The Italian Association for In Vitro Toxicology. 
505 8 |a 1.2 The Italian National Platform for Alternative Methods1.3 The Italian National Reference Centre; 1.4 The Three Rs Declaration of Bologna; 2. ACTIVITIES IN SPAIN RELATED TO IN VITRO PHARMACOTOXICOLOGY; 2.1 The ICLAS/CSIC Working Group on Complementary Methods; 2.2 The Spanish Working Group on Alternative Methods; 2.3 The 3ERRES Mailing List on Alternatives; 2.4 Spanish Scientific Productivity Related to In Vivo and In Vitro Alternative Methods; 2.5 The Inventory of the Spanish Institutions and Scientists Involved in Alternatives to the Use of Laboratory Animals. 
500 |a 2.6 The Spanish Network for the Development of Alternative Methods. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Alternative toxicity testing. 
650 0 |a Toxicology  |x Animal models  |x Moral and ethical aspects. 
650 2 |a Animal Testing Alternatives 
650 6 |a Expérimentation animale  |x Alternative. 
650 6 |a Toxicologie  |x Modèles animaux  |x Aspect moral. 
650 7 |a Alternative toxicity testing  |2 fast 
700 1 |a Combes, Robert. 
700 1 |a Worth, Andrew. 
758 |i has work:  |a The history of alternative test methods in toxicology (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCFBYCj7RdMXgDRVVGyWVqP  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Michael, Balls.  |t History of Alternative Test Methods in Toxicology.  |d San Diego : Elsevier Science & Technology, ©2018  |z 9780128136973 
830 0 |a History of Toxicology and Environmental Health Ser. 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5561525  |z Texto completo 
938 |a ProQuest Ebook Central  |b EBLB  |n EBL5561525 
994 |a 92  |b IZTAP