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Frontiers in Clinical Drug Research. Volume 3, Anti-Allergy Agents.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Rahman, Atta-ur-, 1942-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Sharjah : Bentham Science Publishers, 2018.
Colección:Frontiers in Clinical Drug Research - Anti-Allergy Agents Ser.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro; CONTENTS; PREFACE; List of Contributors; Developing the Perfect Antihistamine for Use in Allergic Conditions: A Voyage in H1 Selectivity; Diana R. Cundell* and Kathryn E. Mickle; INTRODUCTION; Pharmacology of Histamine; Cellular Sources of Histamine and Mechanisms of Release; Mast Cells and the Inflammatory Environment; Histamine and Body Tissues; Antihistamines for the Treatment of Allergies; Nasal Anatomy and Physiology, Allergic Rhinitis, Allergens and Histamine; Allergens and Allergic Rhinitis; The Eye Conjunctiva; Anatomy And Physiology, Allergic Conjunctivitis and Histamine.
  • Allergens and Allergic ConjunctivitisThe Skin; Anatomy and Physiology, Urticaria and Histamine; Allergens and Urticaria; Histamine and the H1 Receptor; First Generation H1 Antihistamines; A History of First Generation Antihistamine Development; Ethylenediamines and Ethanolamines; Piperazines and Piperidines; Phenothiazines and Doxepin; A New Genre of Antihistamines With Powerful Central Nervous System Effects; Side Effects of The First Generation H1 Antihistamines and Toxicity; Central Nervous System H1 Side Effects.
  • Adverse Effects of First Generation H1 Antihistamines Due to Lack of SelectivityToxicity of First Generation Antihistamines; Second Generation H1 Antihistamines; Safer with Less Side Effects; Second Generation Antihistamines With Significant Side Effects: Astemizole, Azelastine and Terfenadine; Second Generation Histamines That are First Generation Analogs; Acrivastine, Cetirizine and Levocetirizine; Cetirizine; Levocetirizine; Second Generation Piperidine Successes; Levocabastine, Loratadine, Desloratadine, Fexofenadine, and Olopatadine; Loratadine; Desloratadine; Fexofenadine.
  • OlopatadineClinical Trial Meta-Analysis Data for Extensively Used Second Generation Antihistamines; CONCLUSION AND FURTHER DIRECTIONS; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Therapeutics in Chronic Spontaneous Urticaria; Alexei Gonzalez-Estrada* and James Fernandez; INTRODUCTION; TREATMENT; ANTIHISTAMINES; H1-Antihistamines; FIRST-GENERATION H1-ANTIHISTAMINES; Hydroxyzine; Doxepin; SECOND-GENERATION H1-ANTIHISTAMINES; Cetirizine; Desloratadine; Loratadine; Fexofenadine; Levocetirizine; Rupatadine; H2-Antihistamines; Cimetidine; Ranitidine; Famotidine.
  • Leukotriene AntagonistMontelukast; Zafirlukast; IMMUNOSUPPRESSIVE MEDICATIONS FOR CSU; Hydroxychloroquine; Colchicine; Dapsone; Sulfasalazine; Methotrexate; Cyclosporine; IMMUNOMODULATORY AGENTS; Omalizumab; Intravenous Immunoglobulin; Corticosteroids; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Research and Development for Anti-Asthmatic Agents with a Focus on Phenotype Changing by Ca2+ Signaling in Airway Smooth Muscle Cells; Hiroaki Kume1,2,*; INTRODUCTION; MECHANISM OF AIRWAY SMOOTH MUSCLE TONE; AIRWAY SMOOTH MUSCLE TONE REGULATED BY KCA CHANNELS.