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|a 1063879676
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|a 9783527807246
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|a 338.476151
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|a UAMI
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| 100 |
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|a Burke, Anthony J.
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|a Catalytic Processes for API Synthesis :
|b From Laboratory to Industry.
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| 260 |
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|a Newark :
|b John Wiley & Sons, Incorporated,
|c 2018.
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| 300 |
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|a 1 online resource (453 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a Cover; Title Page; Copyright; Contents; Foreword; Preface; Abbreviations; Chapter 1 Catalysis and Prerequisites for the Modern Pharmaceutical Industry Landscape; 1.1 Introduction; 1.2 Key Historical Moments in Catalysis Development; 1.3 Key Historical Developments in Catalysis for API Synthesis: Including Catalytic Asymmetric Synthesis; 1.4 Catalytic Synthesis of APIs in the Twenty-First Century: New Developments, Paradigm Shifts, and Future Challenges; 1.5 Conclusions; References; Chapter 2 Catalytic Process Design: The Industrial Perspective; 2.1 Introduction; 2.2 Process Design.
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|a 2.2.1 Heterogeneous and Homogeneous Catalysts2.2.2 Product Safety and Regulatory Requirements; 2.2.3 Control of Residual Metals; 2.2.3.1 Filtration and Adsorption; 2.2.3.2 Extraction and Scavenging; 2.2.3.3 Organic Solvent Nanofiltration (OSN); 2.2.4 Design of Experiment (DoE); 2.2.5 Catalyst Recycling; 2.2.6 Scalability, Safety, and Environmental Aspects; 2.3 Examples of Homogeneous and Heterogeneous Catalytic Reactions in API Manufacture; 2.3.1 Batch Operations; 2.3.2 Continuous-Flow Operations; 2.4 Conclusions; References; Chapter 3 Hydrogenation, Hydroformylation, and Other Reductions.
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|a 3.1 Introduction3.2 Hydrogenation; 3.2.1 Hydrogenation of Alkenes; 3.2.1.1 Enamides; 3.2.2 Hydrogenation of Carbonyl Groups; 3.2.3 Hydrogenation of Imines; 3.3 Transfer Hydrogenation; 3.3.1 On Ketones; 3.3.2 On Imines; 3.4 Reductions with Oxazaborolidine Catalytic Systems; 3.5 Hydroformylation; 3.6 Reductions with Organocatalysts; 3.7 Other Catalytic Reductions; 3.7.1 Reduction of Nitro Units; 3.7.2 Other Reductions; 3.8 Conclusions; References; Chapter 4 Oxidation: Nobel Prize Chemistry Catalysis; 4.1 Introduction; 4.2 Olefin Epoxidation; 4.2.1 Metal-based Electrophilic Methods.
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| 505 |
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|a 4.2.1.1 The Sharpless-Katsuki Asymmetric Epoxidation4.2.1.2 The Jacobsen-Katsuki Asymmetric Epo; 4.2.2 Nucleophilic Methods; 4.2.2.1 Nucleophilic Methods with Hydrogen Peroxide; 4.2.3 Organocatalytic Methods; 4.3 Olefin Dihydroxylation; 4.4 Olefin Aminohydroxylation; 4.5 Sulfur Oxidation; 4.5.1 Synthesis of Sulfoxides -- Use of Titanium, Molybdenum, and Vanadium Catalysts; 4.5.2 Synthesis of Sulfones -- Use of Tungsten Catalysts; 4.6 Catalytic Oxidation of Carbonyls -- Cu/Nitroxyl and Nitroxyl/NOx Catalytic Systems; 4.7 Oxidative Dehydrogenations (ODs); 4.8 Conclusions; References.
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|a Chapter 5 Catalytic Addition Reactions5.1 Introduction; 5.2 1,2-Additions; 5.3 1,4-Additions; 5.4 Conclusions; References; Chapter 6 Catalytic Cross-Coupling Reactions -- Nobel Prize Catalysis; 6.1 Introduction; 6.2 Heck-Mizoroki Reaction; 6.3 The Suzuki-Miyaura Reaction; 6.4 The Buchwald-Hartwig Reaction; 6.5 The Sonogashira-Hagihara Reaction; 6.6 The Allylic Substitution Reaction; 6.7 C-H Activation Processes; 6.8 Oxidative CC Bond Formation; 6.9 Conclusions; References; Chapter 7 Catalytic Metathesis Reactions: Nobel Prize Catalysis; 7.1 Introduction; 7.2 Metathesis with Ru-Based Catalysts.
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| 500 |
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|a 7.3 Mo-Based Metathesis.
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| 590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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| 700 |
1 |
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|a Silva Marques, Carolina.
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| 700 |
1 |
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|a Turner, Nicholas.
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| 700 |
1 |
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|a Hermann, Gesine.
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| 758 |
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|i has work:
|a Catalytic processes for API synthesis (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGfQx3xh4gmhgWGdkg3tgC
|4 https://id.oclc.org/worldcat/ontology/hasWork
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|i Print version:
|a Burke, Anthony J.
|t Catalytic Processes for API Synthesis : From Laboratory to Industry.
|d Newark : John Wiley & Sons, Incorporated, ©2018
|z 9783527342419
|
| 856 |
4 |
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|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5472020
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