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Pharmaceutical crystals : science and engineering /
An important resource that puts the focus on understanding and handling of organic crystals in drug development Since a majority of pharmaceutical solid-state materials are organic crystals, their handling and processing are critical aspects of drug development. Pharmaceutical Crystals: Science and...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, NJ :
John Wiley & Sons,
2018.
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| Edición: | First edition. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Pharmaceutical crystals : |b science and engineering / |c edited by Tonglei Li, Alessandra Mattei. |
| 250 | |a First edition. | ||
| 264 | 1 | |a Hoboken, NJ : |b John Wiley & Sons, |c 2018. | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Crystallography -- Nucleation -- Solid-state characterization techniques -- Intermolecular interactions and computational modeling -- Polymorphism and phase transitions -- Measurement and mathematical relationships of cocrystal thermodynamic properties -- Mechanical properties -- Primary processing of organic crystals -- Secondary processing of organic crystals -- Chemical stability and reaction -- Crystalline nanoparticles. | |
| 588 | 0 | |a Print version record and CIP data provided by publisher. | |
| 520 | |a An important resource that puts the focus on understanding and handling of organic crystals in drug development Since a majority of pharmaceutical solid-state materials are organic crystals, their handling and processing are critical aspects of drug development. Pharmaceutical Crystals: Science and Engineering offers an introduction to and thorough coverage of organic crystals, and explores the essential role they play in drug development and manufacturing. Written contributions from leading researchers and practitioners in the field, this vital resource provides the fundamental knowledge and explains the connection between pharmaceutically relevant properties and the structure of a crystal. Comprehensive in scope, the text covers a range of topics including: crystallization, molecular interactions, polymorphism, analytical methods, processing, and chemical stability. The authors clearly show how to find solutions for pharmaceutical form selection and crystallization processes. Designed to be an accessible guide, this book represents a valuable resource for improving the drug development process of small drug molecules. This important text: -Includes the most important aspects of solid-state organic chemistry and its role in drug development -Offers solutions for pharmaceutical form selection and crystallization processes -Contains a balance between the scientific fundamental and pharmaceutical applications -Presents coverage of crystallography, molecular interactions, polymorphism, analytical methods, processing, and chemical stability Written for both practicing pharmaceutical scientists, engineers, and senior undergraduate and graduate students studying pharmaceutical solid-state materials, Pharmaceutical Crystals: Science and Engineering is a reference and textbook for understanding, producing, analyzing, and designing organic crystals which is an imperative skill to master for anyone working in the field. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Crystals |x Structure. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 0 | |a Drug development. | |
| 650 | 6 | |a Cristaux |x Structure. | |
| 650 | 6 | |a Chimie pharmaceutique. | |
| 650 | 6 | |a Médicaments |x Développement. | |
| 650 | 7 | |a SCIENCE |x Physics |x Crystallography. |2 bisacsh | |
| 650 | 7 | |a Crystals |x Structure |2 fast | |
| 650 | 7 | |a Drug development |2 fast | |
| 650 | 7 | |a Pharmaceutical chemistry |2 fast | |
| 700 | 1 | |a Li, Tonglei, |d 1967- |e editor. | |
| 700 | 1 | |a Mattei, Alessandra, |d 1977 June 18- |e editor. | |
| 758 | |i has work: |a Pharmaceutical crystals (Text) |1 https://id.oclc.org/worldcat/entity/E39PCG8HjYkwyjWGykG9f6YhVC |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |t Pharmaceutical crystals. |b First edition. |d Hoboken, NJ : John Wiley & Sons, 2018 |z 9781119046295 |w (DLC) 2018016966 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5507962 |z Texto completo |
| 880 | 8 | |6 505-00/(S |a 3.2.2.2 Thermogravimetric Analysis (TGA)3.2.3 Spectroscopy; 3.2.3.1 Infrared (IR); 3.2.3.2 Raman Spectroscopy; 3.2.3.3 Solid-state Nuclear Magnetic Resonance (SSNMR); 3.2.4 Water Sorption; 3.2.5 Microscopy; 3.3 Case Study LY334370 Hydrochloride (HCl); 3.4 Summary; References; Chapter 4 Intermolecular Interactions and Computational Modeling; 4.1 Introduction; 4.2 Foundation of Intermolecular Interactions; 4.2.1 Electrostatic Interactions; 4.2.2 van der Waals Interactions; 4.2.3 Hydrogen-bonding Interactions; 4.2.4 π-π Interactions; 4.3 Intermolecular Interactions in Organic Crystals. | |
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