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Modeling and parameter estimation for heterogeneous cell populations /

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Hasenauer, Jan (Autor)
Autores Corporativos: Stuttgart Research Centre for Simulation Technology (sponsoring body.), Universität Stuttgart. Institut für Systemtheorie und Regelungstechnik (sponsoring body.)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin : Logos Verlag Berlin GmbH, 2013.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro; 1 Introduction; 1.1 Research motivation; 1.2 Research topic overview; 1.3 Contribution of this thesis; 1.4 Outline of this thesis; 2 Background; 2.1 Single cells models; 2.2 Cell population models; 2.3 Bayesian parameter estimation in a nutshell; 3 Signal transduction in heterogeneous cell populations; 3.1 Introduction and problem statement; 3.2 Modeling of signal transduction in heterogeneous cell populations; 3.3 Bayesian estimation and uncertainty analysis of population heterogeneity; 3.4 Example: Apoptotic signaling in cancer cell populations; 3.5 Summary and discussion
  • 4 Proliferation of heterogeneous cell populations4.1 Introduction and problem statement; 4.2 Modeling the proliferation of heterogeneous cell populations; 4.3 Bayesian estimation and uncertainty analysis of proliferation dynamics; 4.4 Application example: Proliferation of T lymphocytes; 4.5 Summary and discussion; 5 Conclusion; 5.1 Summary and conclusions; 5.2 Outlook; Appendix