|
|
|
|
| LEADER |
00000cam a2200000Mi 4500 |
| 001 |
EBOOKCENTRAL_on1027203147 |
| 003 |
OCoLC |
| 005 |
20240329122006.0 |
| 006 |
m o d |
| 007 |
cr |n|---||||| |
| 008 |
180303s2018 nju o 000 0 eng d |
| 040 |
|
|
|a EBLCP
|b eng
|e pn
|c EBLCP
|d OCLCQ
|d DEBBG
|d OCLCQ
|d REDDC
|d OCLCF
|d K6U
|d OCLCQ
|d OCLCO
|
| 020 |
|
|
|a 9783527688081
|
| 020 |
|
|
|a 3527688080
|
| 035 |
|
|
|a (OCoLC)1027203147
|
| 050 |
|
4 |
|a TA164
|b .S968 2018
|
| 082 |
0 |
4 |
|a 660.6
|
| 049 |
|
|
|a UAMI
|
| 100 |
1 |
|
|a Lee, Sang Yup.
|
| 245 |
1 |
0 |
|a Synthetic Biology :
|b Parts, Devices and Applications.
|
| 260 |
|
|
|a Newark :
|b John Wiley & Sons, Incorporated,
|c 2018.
|
| 300 |
|
|
|a 1 online resource (428 pages)
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Advanced Biotechnology Ser.
|
| 588 |
0 |
|
|a Print version record.
|
| 505 |
0 |
|
|a Cover; Title Page; Copyright; Contents; About the Series Editors; Part I DNA Synthesis and Genome Engineering; Chapter 1 Competition and the Future of Reading and Writing DNA; 1.1 Productivity Improvements in Biological Technologies; 1.2 The Origin of Mooreâ#x80;#x99;s Law and Its Implications for Biological Technologies; 1.3 Lessons from Other Technologies; 1.4 Pricing Improvements in Biological Technologies; 1.5 Prospects for New Assembly Technologies; 1.6 Beyond Programming Genetic Instruction Sets; 1.7 Future Prospects; References.
|
| 505 |
8 |
|
|a Chapter 2 Trackable Multiplex Recombineering (TRMR) and Next-Generation Genome Design Technologies: Modifying Gene Expression in E. coli by Inserting Synthetic DNA Cassettes and Molecular Barcodes2.1 Introduction; 2.2 Current Recombineering Techniques; 2.2.1 Recombineering Systems; 2.2.2 Current Model of Recombination; 2.3 Trackable Multiplex Recombineering; 2.3.1 TRMR and T2RMR Library Design and Construction; 2.3.2 Experimental Procedure; 2.3.3 Analysis of Results; 2.4 Current Challenges; 2.4.1 TRMR and T2RMR are Currently Not Recursive; 2.4.2 Need for More Predictable Models.
|
| 505 |
8 |
|
|a 2.5 Complementing Technologies2.5.1 MAGE; 2.5.2 CREATE; 2.6 Conclusions; Definitions; References; Chapter 3 Site-Directed Genome Modification with Engineered Zinc Finger Proteins; 3.1 Introduction to Zinc Finger DNA-Binding Domains and Cellular Repair Mechanisms; 3.1.2 Homologous Recombination; 3.1.3 Non-homologous End Joining; 3.2 Approaches for Engineering or Acquiring Zinc Finger Proteins; 3.2.1 Modular Assembly; 3.2.2 OPEN and CoDA Selection Systems; 3.2.3 Purchase via Commercial Avenues; 3.3 Genome Modification with Zinc Finger Nucleases.
|
| 505 |
8 |
|
|a 3.4 Validating Zinc Finger Nuclease-Induced Genome Alteration and Specificity3.5 Methods for Delivering Engineered Zinc Finger Nucleases into Cells; 3.6 Zinc Finger Fusions to Transposases and Recombinases; 3.7 Conclusions; References; Chapter 4 Rational Efforts to Streamline the Escherichia coli Genome; 4.1 Introduction; 4.2 The Concept of a Streamlined Chassis; 4.3 The E. coli Genome; 4.4 Random versus Targeted Streamlining; 4.5 Selecting Deletion Targets; 4.5.1 General Considerations; 4.5.1.1 Naturally Evolved Minimal Genomes; 4.5.1.2 Gene Essentiality Studies.
|
| 505 |
8 |
|
|a 4.5.1.3 Comparative Genomics4.5.1.4 In silico Models; 4.5.1.5 Architectural Studies; 4.5.2 Primary Deletion Targets; 4.5.2.1 Prophages; 4.5.2.2 Insertion Sequences (ISs); 4.5.2.3 Defense Systems; 4.5.2.4 Genes of Unknown and Exotic Functions; 4.5.2.5 Repeat Sequences; 4.5.2.6 Virulence Factors and Surface Structures; 4.5.2.7 Genetic Diversity-Generating Factors; 4.5.2.8 Redundant and Overlapping Functions; 4.6 Targeted Deletion Techniques; 4.6.1 General Considerations; 4.6.2 Basic Methods and Strategies; 4.6.2.1 Circular DNA-Based Method; 4.6.2.2 Linear DNA-Based Method.
|
| 500 |
|
|
|a 4.6.2.3 Strategy for Piling Deletions.
|
| 590 |
|
|
|a ProQuest Ebook Central
|b Ebook Central Academic Complete
|
| 650 |
|
0 |
|a Synthetic biology.
|
| 650 |
|
6 |
|a Biologie synthétique.
|
| 650 |
|
7 |
|a Synthetic biology
|2 fast
|
| 700 |
1 |
|
|a Nielsen, Jens.
|
| 700 |
1 |
|
|a Stephanopoulos, Gregory.
|
| 700 |
1 |
|
|a Smolke, Christina.
|
| 776 |
0 |
8 |
|i Print version:
|a Lee, Sang Yup.
|t Synthetic Biology : Parts, Devices and Applications.
|d Newark : John Wiley & Sons, Incorporated, ©2018
|z 9783527330751
|
| 830 |
|
0 |
|a Advanced Biotechnology Ser.
|
| 856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5309272
|z Texto completo
|
| 938 |
|
|
|a ProQuest Ebook Central
|b EBLB
|n EBL5309272
|
| 994 |
|
|
|a 92
|b IZTAP
|
