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Classical Methods in Structure Elucidation of Natural Products.
Organic chemistry as we know it today originated from a preoccupation with substances isolated from nature. In the period from 1860 to 1960, the main task was to elucidate their molecular structure by way of degradation and synthesis. In light of the limited experimental methods available and the la...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Newark :
John Wiley & Sons, Incorporated,
2017.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Hoffmann, Reinhard W. | |
| 245 | 1 | 0 | |a Classical Methods in Structure Elucidation of Natural Products. |
| 260 | |a Newark : |b John Wiley & Sons, Incorporated, |c 2017. | ||
| 300 | |a 1 online resource (315 pages) | ||
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| 505 | 0 | |a Intro; Title Page; Copyright; Table of Contents; Preface; Hundred Years of Structure Elucidation; References; Part I: Compounds with only Oxygen Functionalities; Chapter 1: Ascorbic Acid; References; Chapter 2: Hinokitiol; References; Chapter 3: Cantharidin; References; Chapter 4: Camphor; References; Chapter 5: α-Terpineol; References; Chapter 6: Lactaroviolin; References; Chapter 7: Santonin; References; Chapter 8: Estrone; References; Chapter 9: α-Tocopherol; References; Part II: Compounds with Nitrogen and Oxygen Functionalities; Chapter 10: Pyridoxine; References; Chapter 11: Muscarine. | |
| 504 | |a ReferencesChapter 12: Lupinine; References; Chapter 13: Lysergic Acid; References; Chapter 14: Riboflavin; References; Chapter 15: Cocaine; References; Chapter 16: Quinine; References; Chapter 17: Colchicine; References; Chapter 18: Luciferin; References; Chapter 19: Strychnine*; References; Part III: Compounds with Additional Functionalities; Chapter 20: Biotin; References; Chapter 21: Thiamine; References; Chapter 22: Griseofulvin; References; Part IV: Compounds without Heteroatom-Functionalities; Chapter 23: Decacyclene; References; Chapter 24: Carotene; References. | ||
| 505 | 8 | |a Part V: Can You Do it Yourself?Chapter 25: Penicillin; References; Index; End User License Agreement. | |
| 520 | |a Organic chemistry as we know it today originated from a preoccupation with substances isolated from nature. In the period from 1860 to 1960, the main task was to elucidate their molecular structure by way of degradation and synthesis. In light of the limited experimental methods available and the lack of established reference compounds, this represented an unparalleled intellectual challenge. This book makes use of twenty-five representative examples to retrace the great accomplishments made by the generation of chemists during this era. At the same time, it questions the reliability of the experimental results when judged by today's criteria, particularly since the structures for numerous natural products are stated as established facts in standard text books. With each chapter devoted to one organic compound, the author combines results from historic experiments to trace a line of evidence that may follow the path put forward by the original contributors. However, in some cases the experimental facts have been combined to form another, hopefully shorter, line of evidence. As a result, readers are able to determine for themselves the 'facts behind the established structure assignments' of a number of important natural products. | ||
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