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Stem cells in birth defects research and developmental toxicology /

This book contains material contributed by forward-looking scientists who work at the interface of stem cell research and applied science with the aim to improve human fetal safety and the understanding of human developmental and degenerative disorders. Provides important platforms and contemporary...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Rasmussen, Theodore P., 1962- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, NJ : John Wiley & Sons, Inc., 2018.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Stem cells in birth defects research and developmental toxicology /  |c edited by Theodore P. Rasmussen. 
264 1 |a Hoboken, NJ :  |b John Wiley & Sons, Inc.,  |c 2018. 
264 4 |c ©2018 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
520 |a This book contains material contributed by forward-looking scientists who work at the interface of stem cell research and applied science with the aim to improve human fetal safety and the understanding of human developmental and degenerative disorders. Provides important platforms and contemporary accounts of the state of stem cell research in the fields of toxicology and teratology. Considers both in vitro uses of stem cells as platforms for teratology and also stem cellopathies, which are in vivo developmental and degenerative disorders. Helps the pharmaceutical industry and safety and environmental authorities validate the status quo of in vitro toxicity test systems based on human pluripotent stem cells and their derivatives"--Provided by publisher. 
505 0 |a The Basics of Stem Cells and Their Utility as Platforms to Model Teratogen Action and Human Developmental and Degenerative Disorders / Bindu Prabhakar, Soowan Lee, and Theodore P. Rasmussen -- Stem Cells and Tissue Engineering Technologies for Advancing Human Teratogen Screening / Jiangwa Xing, Geetika Sahni and Yi-Chin Toh -- Use of Embryoid Bodies for the Detection of Teratogens and Analysis of Teratogenic Mechanisms / Anthony Flamier -- Stem-Cell-Based In vitro Morphogenesis Models to Investigate Developmental Toxicity of Chemical Exposures / Yusuke Marikawa -- RIsk Assessment Using Human Pluripotent Stem Cells: Recent Advances in Developmental Toxicity Screens / Kristen Buck and Nicole I. zur Nieden -- Modeling the Brain in the Culture Dish: Advancements and Applications of Induced Pluripotent Stem-Cell-Derived Neurons / Sandhya Chandrasekaran, Prashanth Rajarajan, Schahram Akbarian, and Kristen Brennand -- Modeling Genetic and Environment Interactions Relevant to Huntington's and Parkinson's Disease in Human Induced Pluripotent Stem Cells (hiPSCs)-Derived Neurons / Piyush Joshi, M. Diana Neely, and Aaron B. Bowman -- Alcohol Effects on Adult Neural Stem Cells -- A Novel Mechanism of Neurotoxicity and Recovery in Alcohol Use Disorders / Rachael A. Olsufka, Hui Peng, Jessica S. Newton, and Kimberly Nixon -- Fetal Alcohol Spectrum Disorders: A Stem-Cellopathy? / Amanda H. Mahnke, Nihal A. Salem, Alexander M. Tseng, Annette S. Fincher, Andrew Klopfer, and Rajesh C. Miranda -- Toxicological Responses in Keratinocyte Interfollicular Stem Cells / Rambon Shamilov and Brian J. Aneskievich -- Stem-Cell Microscale Platforms for Toxicology Screening / Tiago G. Fernandes and Joaquim M.S. Cabral -- HepaRG Cells as a Model for Hepatotoxicity Studies / André Guillouzo and Christiane Guguen-Guillouzo. 
588 0 |a Online resource; title from digital title page (viewed on May 03, 2018). 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Stem cells  |x Research. 
650 0 |a Abnormalities, Human. 
650 1 2 |a Stem Cell Research 
650 2 2 |a Pluripotent Stem Cells  |x drug effects 
650 2 2 |a Fetal Research 
650 2 2 |a Teratogens  |x analysis 
650 2 2 |a Neurodevelopmental Disorders 
650 2 2 |a Toxicity Tests 
650 6 |a Cellules souches  |x Recherche. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Abnormalities, Human  |2 fast 
650 7 |a Stem cells  |x Research  |2 fast 
700 1 |a Rasmussen, Theodore P.,  |d 1962-  |e editor. 
758 |i has work:  |a Stem cells in birth defects research and developmental toxicology (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCG8QDj4bXcmwh4KDMqwtJC  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |t Stem cells in birth defects research and developmental toxicology.  |b First edition.  |d Hoboken, NJ : Wiley, 2018  |z 9781119283218  |w (DLC) 2017056789 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5331601  |z Texto completo 
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