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171104s2017 enk o 000 0 eng d |
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|d K6U
|d OCLCQ
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|a 9780081007426
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|a 0081007426
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|a AU@
|b 000068486657
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|a (OCoLC)1009275607
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|a QD431.5 .P478 2018
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|a 610.28
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|a UAMI
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100 |
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|a Koutsopoulos, Sotirios.
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245 |
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|a Peptide Applications in Biomedicine, Biotechnology and Bioengineering.
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260 |
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|a Cambridge :
|b Elsevier Science,
|c 2017.
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300 |
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|a 1 online resource (655 pages)
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a Front Cover -- Â#x93;Peptide Applications in Biomedicine, Biotechnology and Bioengineering -- Copyright Page -- Contents -- List of contributors -- 1 Peptide synthesis: Methods, trends, and challenges -- 1.1 Introduction -- 1.2 Solid phase peptide synthesis -- 1.3 Solid supports (resins and linkers) -- 1.3.1 Resins -- 1.3.2 Linkers for Fmoc-based SPPS -- 1.4 Protecting groups -- 1.4.1 Nα amino protecting groups -- 1.4.2 Side-chain protecting groups -- 1.5 Coupling reagents -- 1.6 Deprotection: Cleavage solutions
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505 |
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|a 1.7 Microwave-assisted solid-phase peptide synthesis1.8 Green peptide synthesis -- 1.9 Future challenges: Conclusions -- References -- 2 Synthetic approaches of naturally and rationally designed peptides and peptidomimetics -- 2.1 Natural and rationally designed peptides -- 2.1.1 Cyclic peptides -- 2.1.2 Disulfide-rich peptides -- 2.1.2.1 Conotoxins -- 2.1.2.2 Cyclotides -- 2.1.3 Cyclodepsipeptides -- 2.1.3.1 â#x80;#x9C;Head-to-tailâ#x80;#x9D; cyclodepsipeptides -- 2.1.3.2 â#x80;#x9C;Head-to-side-chainâ#x80;#x9D; cyclodepsipeptides -- 2.1.4 Lantibiotics -- 2.1.5 Stapled peptides
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|a 2.2 Peptidomimetics2.2.1 Peptoids and Peptoid derivatives -- 2.2.2 AA-peptides -- 2.2.3 Azapeptides -- 2.2.4 Urea-based peptidomimetics -- 2.2.5 Nonpeptide-based peptidomimetics -- Acknowledgments -- References -- 3 Applications of de novo designed peptides -- 3.1 Introduction -- 3.2 Peptide building blocks -- 3.2.1 α-Helices, helical bundles, and coiled coils -- 3.2.1.1 α-Helices -- 3.2.1.2 Coiled coils -- 3.2.1.3 Helical bundles -- 3.2.2 β-Strands and sheets -- 3.2.2.1 β-Strands -- 3.2.2.2 β-Sheets -- 3.2.3 Collagens
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|a 3.3 De novo designed peptide structures and their applications3.3.1 Tissue engineering and regeneration -- 3.3.1.1 Scaffolds from self-assembled β-structured components -- 3.3.1.2 SAFs (self-assembling fibers) from α-helical building blocks -- 3.3.1.3 Tissue engineering and regeneration with collagen-mimetic peptides -- 3.3.1.4 Short peptide motifs as molecular signals -- 3.3.2 Drug encapsulation, release, and delivery -- 3.3.2.1 Drug encapsulation and release from hydrogels -- 3.3.2.2 Discrete structures for encapsulation, release, and delivery
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|a 3.3.2.3 Translocating and permeating peptides for drug delivery3.3.3 Antigen display and vaccine development -- 3.3.4 Membrane protein stabilization -- 3.3.4.1 α-Helical amphipathic peptides -- 3.3.4.2 Short, self-assembling peptides -- 3.3.5 Imaging contrast agents -- 3.3.5.1 Translocating and targeting peptide conjugates -- 3.3.5.2 De novo designed chelating peptides -- 3.3.6 3D printingâ#x80;#x94;peptide bioinks -- 3.3.7 Nanoparticle and nanowire synthesis -- 3.3.7.1 Peptide-directed nanoparticle synthesis -- 3.3.7.2 Nanowire synthesis -- 3.4 Conclusions and outlook
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|a ""3.5 Summary of de novo designed peptides""
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|a Annotation
|b This text summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. The book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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0 |
|a Peptides-Laboratory manuals.
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776 |
0 |
8 |
|i Print version:
|a Koutsopoulos, Sotirios.
|t Peptide Applications in Biomedicine, Biotechnology and Bioengineering.
|d Cambridge : Elsevier Science, ©2017
|z 9780081007365
|
856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5115954
|z Texto completo
|
938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL5115954
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994 |
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|a 92
|b IZTAP
|