CYP2D6.

In this book of nine chapters, expert authors explore the properties of CYP2D6 with respect to the basic genetic aspects, its interactions with drugs that are substrates and/or inhibitors, and the implications of the pharmacogenetics of CYP2D6 in the clinical context.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Baumann, Pierre
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Future Science Group, 2014.
Temas:
Cytochrome P-450 > Physiological effect.
Cytochrome P-450 > Genetics.
Cytochrome P-450 > Therapeutic use.
Cytochrome P-450 > Effets physiologiques.
Cytochrome P-450 > Génétique.
Cytochrome P-450 > Emploi en thérapeutique.
Cytochrome P-450 > Physiological effect
Acceso en línea:Texto completo

MARC

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100 1 |a Baumann, Pierre. 
245 1 0 |a CYP2D6. 
260 |a London :  |b Future Science Group,  |c 2014. 
300 |a 1 online resource (159 pages) 
336 |a text  |b txt  |2 rdacontent 
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588 0 |a Print version record. 
505 0 |a CYP2D6: genetics, pharmacology and clinical relevance -- A history and overview of phenotypic variability in CYP2D6 activity -- Genetic variability of CYP2D6: basic and clinical aspects -- CYP2D6: interethnic variability -- CYP2D6 ethnic variability in Hispanics -- Structural properties of CYP2D6: requirements for substrates and inhibitors -- CYP2D6 substrates and drug metabolism -- _GoBack -- _ENREF_1 -- _ENREF_2 -- _ENREF_3 -- _ENREF_4 -- _GoBack -- _ENREF_1 -- _ENREF_2 -- _ENREF_3 -- _ENREF_4 -- _ENREF_5 -- _ENREF_6 -- _ENREF_7 -- _ENREF_8 
505 8 |a _ENREF_9_ENREF_10 -- _ENREF_11 -- _ENREF_12 -- _ENREF_13 -- _ENREF_14 -- _ENREF_15 -- _ENREF_16 -- _ENREF_17 -- _ENREF_18 -- _ENREF_19 -- _ENREF_20 -- _ENREF_21 -- _ENREF_22 -- _ENREF_23 -- _ENREF_24 -- _ENREF_25 -- _ENREF_26 -- _ENREF_27 -- _ENREF_28 -- _ENREF_29 -- _ENREF_30 -- _ENREF_31 -- _ENREF_32 -- _ENREF_33 -- _ENREF_34 -- _ENREF_35 -- _ENREF_36 -- _ENREF_38 -- _ENREF_39 -- _ENREF_40 -- _ENREF_41 -- _ENREF_42 -- _ENREF_43 -- _ENREF_44 -- _ENREF_45 -- OLE_LINK1 -- OLE_LINK2 -- OLE_LINK5 -- OLE_LINK6 
505 8 |a OLE_LINK3OLE_LINK2 -- OLE_LINK1 -- OLE_LINK28 -- OLE_LINK27 -- OLE_LINK30 -- OLE_LINK29 -- OLE_LINK32 -- OLE_LINK31 -- OLE_LINK34 -- OLE_LINK33 -- OLE_LINK36 -- OLE_LINK35 -- OLE_LINK38 -- OLE_LINK37 -- OLE_LINK24 -- OLE_LINK23 -- OLE_LINK40 -- OLE_LINK39 -- OLE_LINK42 -- OLE_LINK41 -- OLE_LINK44 -- OLE_LINK43 -- OLE_LINK46 -- OLE_LINK45 -- OLE_LINK48 -- OLE_LINK47 -- _GoBack -- OLE_LINK9 -- OLE_LINK8 -- OLE_LINK7 -- OLE_LINK13 -- OLE_LINK12 -- OLE_LINK22 -- OLE_LINK15 -- OLE_LINK14 -- OLE_LINK11 -- OLE_LINK10 
505 8 |a OLE_LINK17OLE_LINK16 -- OLE_LINK19 -- OLE_LINK18 -- _GoBack -- OLE_LINK2 -- OLE_LINK3 -- Molecular mechanism of CYP2D6-mediated oxidation -- Substrate binding to CYP2D6 active site -- CYP2D6 substrates that are commercially available drugs -- Implications of variability in exposure to CYP2D6 substrates -- Modeling of CYP2D6 genotype-related variability in the pharmacokinetics of CYP2D6 substrates -- Assessment of CYP2D6-mediated elimination in the early stages of drug development -- _GoBack -- _GoBack -- _ENREF_1 -- _ENREF_2 -- _ENREF_3 -- _ENREF_4 
505 8 |a _ENREF_5_ENREF_6 -- _ENREF_7 -- _ENREF_8 -- _ENREF_9 -- _ENREF_10 -- _ENREF_11 -- _ENREF_12 -- _ENREF_13 -- _ENREF_14 -- _ENREF_15 -- _ENREF_16 -- _ENREF_17 -- _ENREF_18 
520 |a In this book of nine chapters, expert authors explore the properties of CYP2D6 with respect to the basic genetic aspects, its interactions with drugs that are substrates and/or inhibitors, and the implications of the pharmacogenetics of CYP2D6 in the clinical context. 
504 |a Includes bibliographical references at the end of each chapters and index. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Cytochrome P-450  |x Physiological effect. 
650 0 |a Cytochrome P-450  |x Genetics. 
650 0 |a Cytochrome P-450  |x Therapeutic use. 
650 6 |a Cytochrome P-450  |x Effets physiologiques. 
650 6 |a Cytochrome P-450  |x Génétique. 
650 6 |a Cytochrome P-450  |x Emploi en thérapeutique. 
650 7 |a Cytochrome P-450  |x Physiological effect  |2 fast 
776 0 8 |i Print version:  |a Baumann, Pierre.  |t CYP2D6: Genetics, Pharmacology and Clinical Relevance.  |d London : Future Science Group, ©2014  |z 9781780844640 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5092359  |z Texto completo 
936 |a BATCHLOAD 
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938 |a YBP Library Services  |b YANK  |n 14880269 
994 |a 92  |b IZTAP 

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