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Handbook of Epigenetics : the New Molecular and Medical Genetics.
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Saint Louis :
Elsevier Science,
2017.
|
| Edición: | 2nd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Title page; Copyright page; Contents; Contributors; Preface; Section I
- Overview; Chapter 1
- An Overview of Epigenetics; Introduction; Molecular Mechanisms of Epigenetics; Methods in Epigenetics; Model Organisms of Epigenetics; Factors Influencing Epigenetic Changes; Evolutionary Epigenetics; Epigenetic Epidemiology; Epigenetics and Human Disease; Epigenetic Therapy; The Future of Epigenetics; Conclusions; References; Section II
- Molecular Mechanisms of Epigenetics; Chapter 2
- Mechanisms of DNA Methylation and Demethylation During Mammalian Development; Introduction.
- DNA MethylationMaintenance DNA Methylation; DNMT1; UHRF1; De Novo DNA Methylation; DNMT3A and DNMT3B; DNMT3L; DNA Demethylation; Passive DNA Demethylation; Active DNA Demethylation; TET Proteins; TET-Dependent Demethylation Pathways; TET Proteins in Development; Conclusions; Glossary; Abbreviations; Acknowledgments; References; Chapter 3
- Mechanisms of Histone Modifications; Introduction; Histone Modifications; Proline Isomerization; Citrullination; Ubiquitination; Role of Histone Ubiquitination in Transcription Regulation; Role of Histone Ubiquitination in DNA Damage Response; Sumoylation.
- ADP-RibosylationPhosphorylation; Role of Histone Phosphorylation in Transcription Regulation; Role of Histone Phosphorylation in DNA Damage Response; Methylation; Role of Histone Methylation in Transcription Regulation; Role of Histone Methylation in DNA Repair; Acetylation; GNAT Superfamily; MYST Superfamily; P300/CBP; Nuclear Hormone-Related HATs; HAT Complexes; Histone Deacetylases; Role of Histone Acetylation in Transcription Regulation; Role of Histone Acetylation in DNA Repair; Conclusions; References; Chapter 4
- The Epigenetics of Noncoding RNA; Introduction; The Noncoding RNA.
- Genetics and EpigeneticsEpigenetic Regulation of miRNA Expression; Epitranscriptomics of miRNAs; Regulation of Epigenetics by miRNAs; Plausible Interdependence Between miRNA Targeting and mRNA Methylation; Epigenetic Regulation of lncRNAs; Epitranscriptomics of lncRNA; Regulation of Epigenetics by lncRNAs; Conclusions; Abbreviations; Acknowledgments; References; Chapter 5
- Prions and Prion-Like Phenomena in Epigenetic Inheritance; Structural Heredity; Prions of Saccharomyces cerevisiae and Podospora anserina; Self Driven Assembly of Hsp60 Mitochondrial Chaperonin.
- Cytotaxis of Cilia and Other Complex StructuresMixed Heredity: A Prion That Propagates by Covalent Autoactivation; Regulatory Inheritance; The Lactose Operon and its Positive Feedback Loop; Crippled Growth, a Self-Sustained and Mitotically Inheritable Signaling Pathway in the Filamentous Fungus Podospora anserina; The White/Opaque Switch of Candida albicans, an Epigenetic Switch at the Transcription Level; Conclusions; References; Chapter 6
- Higher-Order Chromatin Organization in Diseases: From Chromosomal Position Effect to Phenotype Variegation; Introduction; CPE in Model Organisms.