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170715s2017 mou of 000 0 eng d |
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|a 9780128054772
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|a 0128054778
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|b 000068486519
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|a (OCoLC)993772349
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|a QH450
|b .H363 2017
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|a 572.865
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|a UAMI
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|a Tollefsbol, Trygve O.
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|a Handbook of Epigenetics :
|b the New Molecular and Medical Genetics.
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|a 2nd ed.
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|a Saint Louis :
|b Elsevier Science,
|c 2017.
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300 |
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|a 1 online resource (684 pages)
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a Cover; Title page; Copyright page; Contents; Contributors; Preface; Section I -- Overview; Chapter 1 -- An Overview of Epigenetics; Introduction; Molecular Mechanisms of Epigenetics; Methods in Epigenetics; Model Organisms of Epigenetics; Factors Influencing Epigenetic Changes; Evolutionary Epigenetics; Epigenetic Epidemiology; Epigenetics and Human Disease; Epigenetic Therapy; The Future of Epigenetics; Conclusions; References; Section II -- Molecular Mechanisms of Epigenetics; Chapter 2 -- Mechanisms of DNA Methylation and Demethylation During Mammalian Development; Introduction.
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|a DNA MethylationMaintenance DNA Methylation; DNMT1; UHRF1; De Novo DNA Methylation; DNMT3A and DNMT3B; DNMT3L; DNA Demethylation; Passive DNA Demethylation; Active DNA Demethylation; TET Proteins; TET-Dependent Demethylation Pathways; TET Proteins in Development; Conclusions; Glossary; Abbreviations; Acknowledgments; References; Chapter 3 -- Mechanisms of Histone Modifications; Introduction; Histone Modifications; Proline Isomerization; Citrullination; Ubiquitination; Role of Histone Ubiquitination in Transcription Regulation; Role of Histone Ubiquitination in DNA Damage Response; Sumoylation.
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|a ADP-RibosylationPhosphorylation; Role of Histone Phosphorylation in Transcription Regulation; Role of Histone Phosphorylation in DNA Damage Response; Methylation; Role of Histone Methylation in Transcription Regulation; Role of Histone Methylation in DNA Repair; Acetylation; GNAT Superfamily; MYST Superfamily; P300/CBP; Nuclear Hormone-Related HATs; HAT Complexes; Histone Deacetylases; Role of Histone Acetylation in Transcription Regulation; Role of Histone Acetylation in DNA Repair; Conclusions; References; Chapter 4 -- The Epigenetics of Noncoding RNA; Introduction; The Noncoding RNA.
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|a Genetics and EpigeneticsEpigenetic Regulation of miRNA Expression; Epitranscriptomics of miRNAs; Regulation of Epigenetics by miRNAs; Plausible Interdependence Between miRNA Targeting and mRNA Methylation; Epigenetic Regulation of lncRNAs; Epitranscriptomics of lncRNA; Regulation of Epigenetics by lncRNAs; Conclusions; Abbreviations; Acknowledgments; References; Chapter 5 -- Prions and Prion-Like Phenomena in Epigenetic Inheritance; Structural Heredity; Prions of Saccharomyces cerevisiae and Podospora anserina; Self Driven Assembly of Hsp60 Mitochondrial Chaperonin.
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|a Cytotaxis of Cilia and Other Complex StructuresMixed Heredity: A Prion That Propagates by Covalent Autoactivation; Regulatory Inheritance; The Lactose Operon and its Positive Feedback Loop; Crippled Growth, a Self-Sustained and Mitotically Inheritable Signaling Pathway in the Filamentous Fungus Podospora anserina; The White/Opaque Switch of Candida albicans, an Epigenetic Switch at the Transcription Level; Conclusions; References; Chapter 6 -- Higher-Order Chromatin Organization in Diseases: From Chromosomal Position Effect to Phenotype Variegation; Introduction; CPE in Model Organisms.
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500 |
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|a Telomeric Position Effect.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Epigenetics
|v Periodicals.
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650 |
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|a Epigenetics
|v Handbooks, manuals, etc.
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650 |
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|a Épigénétique
|v Périodiques.
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650 |
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|a Épigénétique
|v Guides, manuels, etc.
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650 |
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|a Epigenetics
|2 fast
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655 |
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7 |
|a Handbooks and manuals
|2 fast
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655 |
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7 |
|a Periodicals
|2 fast
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758 |
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|i has work:
|a Handbook of epigenetics (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCFWCymmVPyRM8d6bMhDJfy
|4 https://id.oclc.org/worldcat/ontology/hasWork
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776 |
0 |
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|i Print version:
|a Tollefsbol, Trygve.
|t Handbook of Epigenetics : The New Molecular and Medical Genetics.
|d Saint Louis : Elsevier Science, ©2017
|z 9780128053881
|
856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=4910280
|z Texto completo
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938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL4910280
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994 |
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|a 92
|b IZTAP
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