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Q Fever /
Information on the changing epidemiology and expanding nosological range of Q fever in humans has gained much attention in the past decade. Q fever is a zoonotic disease caused by the highly infectious pathogen Coxiella burnetii and has global distribution with important health, social and economic...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Gistrup, Denmark :
River Publishers,
[2017]
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| Colección: | River Publishers series in research and business chronicles: biotechnology and medicine ;
volume 8. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Preface xi
- List of Figures xiii
- List of Tables xxi
- List of Abbreviations xxv
- Introduction 1
- 1 Historical Notes 5
- 2 Etiology and Taxonomy 9
- 3 Morphological Features, Development Cycle, and Interaction with Cells 13
- 4 Ultrastructure of Coxiella burnetii and Electron Microscopic Diagnosis of Q Fever 17
- 4.1 Light Microscopic Morphology of C. burnetii 17
- 4.2 Ultrastructure of the Agent and Electron Microscopic Diagnosis of the Disease 20
- 4.2.1 Placentas in Abortions and Births of Dead and Unviable Offspring 20
- 4.2.2 Blood 24
- 4.2.3 Chicken Embryos 28
- 4.2.4 White Mice 29
- 4.2.5 Guinea Pigs 32
- 5 Isolation and Cultivation of Coxiella burnetii 39
- 5.1 Strains Isolated from Sheep 42
- 5.1.1 Abortions, Stillbirths, and Births to Non-viable Offspring 42
- 5.1.2 Pneumonia in Sheep 47
- 5.1.3 Mastitis in Sheep 48
- 5.1.4 Latent Coxiellosis in Sheep 50
- 5.2 Strains Isolated from Goats 50
- 5.2.1 Abortions, Stillbirths, and Births to Non-viable Offspring 50
- 5.2.2 Pneumonia in Goats 51
- 5.2.3 Mastitis in Goats 51
- 5.2.4 Isolation of C. burnetii from Blood in Goat Herds with Active Q Fever 57
- 5.2.5 Latent Coxiellosis in Goats 57
- 5.3 Strains Isolated from Cattle 57
- 5.3.1 Abortions, Stillbirths, and Births to Non-viable Calves 57
- 5.3.2 Pneumonia in Calves 58
- 5.3.3 Mastitis in Cows 58
- 5.3.4 Metritis and Endometritis 59
- 5.3.5 Coxiella burnetii Isolation from the Blood of Cattle in Active Foci of Q Fever 61
- 5.3.6 Isolation of C. burnetii from Wild Animal Species and Arthropods 61
- 6 Virulence and Pathogenicity 71
- 7 Antigens and Phase Variability 75
- 8 Serology 77
- 8.1 Serological Reactions 77
- 8.2 Serological Test's Examinations 80
- 8.2.1 Serological Data for the State of Agricultural Foci of Q Fever in Bulgaria 80
- 8.3 Serological Status of the Infection Caused by Coxiella burnetii among Domestic Animals During the Epidemic of Q Fever in Humans in Etropole-2002
- 83
- 8.4 Serological Status of Infection with Coxiella burnetii among Domestic Animals During the Epidemic of Q Fever in Humans in the Region of Botevgrad-2004.
- 10 Clinical Picture 155
- 10.1 Clinical Course of Q Fever in Animals 155
- 10.2 Clinical Observations in Sheep 157
- 10.2.1 Latent Form 157
- 10.2.2 Abortions, Premature Births, Stillbirths, and Not Viable Lambs 158
- 10.2.3 Pneumonias in Sheep 159
- 10.2.4 Flu-Like Form in Sheep 162
- 10.2.5 Mastitis in Sheep 162
- 10.3 Clinical Observations in Goats 163
- 10.3.1 Latent Form 163
- 10.3.2 Abortion in Goats, Premature Births, Stillborn, and Non-viable Offsprings 164
- 10.3.3 Respiratory Form in Goats 165
- 10.3.4 Flu-Like Form in Goats 165
- 10.3.5 Mastitis in Goats 166
- 10.4 Clinical Observations in Cattle 166
- 10.4.1 Latent Form 166
- 10.4.2 Abortions in Cows, Premature Births, Stillborn, and Non-viable Calves 167
- 10.4.3 Clinical Signs of the Dry Cows after Experimental Infection 168
- 10.4.4 Pneumonias in Calves 169
- 10.4.5 Endometritis, Metritis, and Infertility 169
- 10.4.6 Mastitis in Cows 171
- 10.4.7 Syndrome of Prolonged Reduction of Milk Production 172
- 10.4.8 Clinical Signs in Some Laboratory Animals 172
- 10.4.9 Analysis of the Clinical Data in Animals 176
- 10.4.10 Clinical Course of Q Fever in Humans 181
- 11 Pathogenesis and Pathological Morphology 185
- 11.1 Pathomorphological Investigations in Domestic Ruminants with Etiologically Proven Q Fever 189
- 11.1.1 Macroscopic Picture 189
- 11.1.2 Microscopic Picture 191
- 11.2 Pathomorphological Investigations in Some Laboratory Animals with Etiologically Proven Q Fever 196
- 11.2.1 Macroscopic Picture 196
- 11.2.2 Microscopic Picture in Rabbits 198
- 12 Epizootiology and Epidemiology 205
- 12.1 State of the Natural Foci of Q Fever in Bulgaria 210
- 12.1.1 Ticks 210
- 12.2 Wild Mammals and Birds 214
- 12.3 Agricultural Foci of Q Fever in Bulgaria 217
- 12.3.1 General Characteristics 217
- 12.4 Internal Structure of the Agricultural Foci 218
- 12.5 Categories of Animals in the Agricultural Foci 219
- 12.6 Etiologically Proven Clinical Forms of Q Fever in the AF 219.
- 12.7 Autonomous Circulation Circle and Cyclical Reproduction of the Infection with C. burnetii in the Agricultural Foci 219
- 12.8 Activity of Agricultural Foci and Epidemics of Q Fever in Humans 221
- 12.9 Relationships between Natural and Agricultural Foci of Q Fever 221
- 12.10 Epidemiological Particularities in Humans 225
- 12.11 Analysis of Epizootiological and Epidemiological Data 231
- 13 Sensitivity to Antibiotics and Treatment 239
- 13.1 Sensitivity of C. burnetii to Certain Antibiotics Depending on Its Phase State 244
- 14 Prevention and Control 251
- 14.1 System for Monitoring, Prevention, and Fight against Q Fever 255
- 14.1.1 General Preventive Measures and Epidemiological Control 255
- 14.1.2 Measures to Combat the Disease 258
- Bibliography 261
- Index 311
- About the Author 317.