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|a 990754270
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|a 9781681081878
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|a 616.398
|2 23
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|a UAMI
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| 245 |
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|a Anti-obesity drug discovery and development.
|n Volume 3 /
|c editors, Atta-ur-Rahman, M. Iqbal Choudhary.
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| 260 |
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|a Sharjah :
|b Bentham Science Publishers,
|c 2017.
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| 300 |
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|a 1 online resource (245 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a PREFACE; List of Contributors ; Current Status of Medical Therapy and New Targets for Anti-Obesity Drug Development ; Chihiro Okuma, Yukihito Ishii and Takeshi Ohta*; INTRODUCTION; Approved Drugs; Phentermine; Mazindol; Fenfluramine/Dexfenfluramine; Orlistat; Shibutramine; Rimonabant; Qsymia; BELVIQ (Lorcaserin); Contrave; New Drug Targets (Table 3); Late Phase Clinical Development; Early Phase Clinical Stage Development or Pre-Clinical Development Stage Late Phase Clinical Development; Future Prospects; Obesity Animal Models; ob/ob Mouse; db/db Mouse; KK-Ay Mouse; TSOD Mouse.
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| 505 |
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|a SDT fatty RatZF Rat; ZDF Rat; cp/cp Rat; WBN/Kob fatty Rat; DIO Models; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Unravelling Potential Anorexigen Effects of Nesfatin-1: How Homeostatic Mechanisms Help Balance Excess Calories ; Carmine Finelli*; INTRODUCTION; Nesfatin-1/NUCB-2 and Anorexigenic Effect; The Oxytocin Pathway in Nesfatin-1's Inhibitory Effect on Food Intake; Nesfatin-1 and CRF; Nesfatin-1 and Anti-Obesity Treatment; Nesfatin-1 and Food Behaviour Control; Nesfatin-1 and Signaling Pathway; Nesfatin-1 and Eating Disorders; CONCLUSIVE REMARKS; CONFLICT OF INTEREST.
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|a ACKNOWLEDGEMENTSABBREVIATIONS; REFERENCES; Proteomics in the Characterization of New Target Therapies in Pediatric Obesity Treatment ; Gillian E. Walker1,*, Marilisa De Feudis1, Marta Roccio1, Gianni Bona2 and Flavia Prodam2; INTRODUCTION; CHILDHOOD OBESITY: PATHOLOGICAL BASIS; Genetic Considerations for Childhood Obesity; Energy Homeostasis Dysregulation; Pathophysiology of Adipose Tissue; PROTEOMICS; Gel Based Methods; Non Gel Based Methods: Mass Spectrometry (MS); Chips; Challenges; PROTEOMIC STUDIES OF ADIPOSE TISSUE; WAT Depots; WAT Secretome; BAT; Stromal-Vascular Fraction (SVF).
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|a PROTEOMIC STUDIES IN ADIPOCYTES: STEM CELLS AND CELL LINESAdipogenesis: Adipo-proteomics; Murine 3T3-L1 Preadipocytes; Adipocyte-Derived Stem Cells (ASCs); Adipocyte Secretome; Post-Translational Modifications (PTMs); PROTEOMIC PROFILING: TISSUES AND CIRCULATION; Fetal Programming: Tissue-Specific Biomarkers; Circulating Biomarkers; Urine Biomarkers; OUTLOOKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; ABBREVIATIONS; REFERENCES.
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| 505 |
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|a Relationship Between Hormonal Milieu and Oxidative Stress in Childhood Obesity: A Physiopathological Basis for Antioxidant Treatment and Prevention of Cardiovascular Risk Antonio Mancini*, Francesco Leo, Chantal Di Segni, Sebastiano Raimondo and Aurora Natalia Rossodivita; INTRODUCTION; OBESITY AND OXIDATIVE STRESS; Hormones and Inflammatory Molecules Produced by or Related to Adipose Tissue; Oxidative Stress in Childhood Obesity; HORMONAL REGULATION OF ANTIOXIDANT SYSTEMS AND THEIR DERANGEMENT IN CHILDHOOD OBESITY; Growth Hormone (GH); Thyroid; Adrenal Glands; Gonads.
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| 500 |
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|a Adipose tissue (Leptin and Kisspeptin).
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| 590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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| 590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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| 650 |
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|a Appetite depressants.
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| 650 |
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|a Obesity.
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| 650 |
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2 |
|a Appetite Depressants
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| 650 |
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2 |
|a Obesity
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| 650 |
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6 |
|a Anorexigènes.
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| 650 |
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6 |
|a Obésité.
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| 650 |
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|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
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| 650 |
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|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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| 650 |
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|a MEDICAL
|x Diseases.
|2 bisacsh
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|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
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| 650 |
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|a MEDICAL
|x Internal Medicine.
|2 bisacsh
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| 650 |
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|a Appetite depressants
|2 fast
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| 650 |
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|a Obesity
|2 fast
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| 700 |
1 |
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|a Rahman, Atta-ur-
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| 700 |
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|a Choudhary, M. Iqbal.
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| 776 |
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|i Print version:
|a Rahman, Atta-ur.
|t Anti-Obesity Drug Discovery and Development Volume 3.
|d Sharjah : Bentham Science Publishers, ©2017
|z 9781681081885
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| 830 |
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0 |
|a Anti-Obesity Drug Discovery and Development.
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| 856 |
4 |
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|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=4877812
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