Seizures in Critical Care : a Guide to Diagnosis and Therapeutics.
Updated and expanded to provide the neurologic, intensive and critical care communities a comprehensive guide to common critical care illnesses and seizures, this third edition remains the premier resource on seizures in critical care. In addition to covering etiology, pathophysiology, diagnosis, di...
Clasificación: | Libro Electrónico |
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Autor principal: | |
Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Cham :
Springer International Publishing,
2017.
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Edición: | 3rd ed. |
Colección: | Current clinical neurology.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Series Editor Introduction; Contents; Contributors; Part I: General Section; 1: Status Epilepticus
- Lessons and Challenges from Animal Models; Introduction; History and Definition of SE; Epidemiology; Etiology; Animal Models of SE; Electrical Stimulation Models; Chemical Models of SE: Pilocarpine and Lithium-Pilocarpine; Studies of the Transition from Single Seizures to SE: GABAAR; Studies of the Transition from Single Seizures to SE: NMDAR; Chemical Models of SE: Kainic Acid; Chemical Models of SE: Nerve Agents; In Vitro Models Used to Study Basic Physiology of SE; Brain Slices.
- 4-Aminopyridine ModelLow Magnesium Model; High Potassium Model; Organotypic Slice Culture Model; Other Techniques; Intrinsic Optical Imaging; Dissociated Cultures; Pathophysiological Changes During SE; Lessons from Animal Models of SE; SE Is Maintained by an Underlying Change in Limbic Circuit Excitability That Does Not Depend on Continuous Seizure Activity; The Initiation and Maintenance Phases of SE Are Pharmacologically Distinct; Initiation Is Accompanied by a Loss of GABA Inhibition; Maintenance of SSSE Depends on the Activation of NMDA Receptors.
- Time-Dependent Development of Pharmacoresistance Maladaptive Seizure-Induced Receptor Trafficking Plays a Role in the Development of Pharmacoresistance; Potentiation of NMDA Synaptic Responses May Play a Role in Maintaining SE; Therapeutic Implications of Seizure-Associated Receptor Trafficking; The Case for Polytherapy; If Treatment Is Delayed, Triple Therapy May Be Needed; Timing of Polytherapy Is Critical; The Earlier the Better; Issues Commonly Encountered in Translational Research; Conclusions; References; 2: Impact of Seizures on Outcome; Introduction.
- Continuous Electroencephalogram Monitoring Terminology; Literature Search Methods; Electrographic Seizures in the Intensive Care Unit; Outcome in Sepsis; Outcome in Traumatic Brain Injury; Outcome in Subarachnoid Hemorrhage; Outcome in Stroke; Outcome After Cardiac Surgery; Outcome After Cardiac Arrest; Outcome in Tumors; Pediatric Outcome; Conclusions; References; 3: Diagnosing and Monitoring Seizures in the ICU: The Role of Continuous EEG for Detection and Management of Seizures in Critically Ill Patients, Including the Ictal-Interictal Continuum; Introduction; How to Monitor.
- Data Analysis Who to Monitor; EEG Patterns Encountered During EEG Monitoring; How Long to Monitor; Cost-Effectiveness; Future Directions; Summary; References; 4: Seizures and Quantitative EEG; Introduction; Overview of Quantitative EEG Methods; Amplitude-Based Methods; Displays Derived from Spectrograms; Methods for Monitoring Burst Suppression; Automated Seizure Detection; Automated Detection of Other Epileptiform Patterns; Fundamentals of Spectrograms; Motivation for Spectral Analysis; Spectral Decomposition: Fourier Transforms and the "FFT."