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|a 986067418
|a 986465018
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|a 9781118647127
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|b .S663 2017
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|a 572.8/633
|2 23
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|a UAMI
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|a Li, Xiu-Qing.
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|a Somatic Genome Variation.
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| 260 |
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|a Somerset :
|b John Wiley & Sons, Incorporated,
|c 2017.
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| 300 |
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|a 1 online resource (454 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a Cover; Title Page; Copyright; Contents; List of Contributors; Preface and Introduction; Acknowledgments; About the Editor; Part I Somatic Genome Variation in Animals and Humans; Chapter 1 Polyploidy in Animal Development and Disease; 1.1 Introduction; 1.2 Mechanisms Inducing Somatic Polyploidy; 1.2.1 Cell Fusion; 1.2.2 Acytokinetic Mitosis; 1.2.3 Endomitosis; 1.2.4 Endoreplication; 1.2.5 Gene Amplification; 1.2.6 Ploidy Reversal; 1.3 The Core Cell Cycle Machinery; 1.4 Genomic Organization of Polyploid Cells.
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|a 1.5 Endoreplication: An Effective Tool for Post-Mitotic Growth and Tissue Regeneration1.6 Initiation of Endoreplication in Drosophila; 1.6.1 Endocycle Entry in Ovarian Follicle Cells; 1.6.2 Signaling Pathways Regulating Endocycle Entry in Follicle Cells; 1.6.3 Endocycle Entry in Other Tissues; 1.7 Mechanisms of Endocycle Oscillations in Drosophila; 1.7.1 An Autonomous Oscillator Drives Endocycling in the Salivary Gland; 1.7.2 Alternative Modes of Endoreplication; 1.8 Gene Amplification in Drosophila Follicle Cells; 1.8.1 Molecular Mechanism of Gene Amplification.
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|a 1.8.2 The Endocycle-to-Amplification Switch1.9 Endocycle Entry in the Trophoblast Lineage; 1.10 Mechanisms of Endocycle Oscillations in Trophoblast Giant Cells; 1.11 Cardiomyocytes; 1.11.1 Upstream Control of Cardiomyocyte Polyploidization; 1.11.2 Mechanisms of Cardiomyocyte Polyploidization; 1.11.3 Polyploidization as a Response to Tissue Damage; 1.12 Hepatocytes; 1.12.1 Mechanisms of Hepatocyte Polyploidization; 1.12.2 The Ploidy Conveyor Model; 1.12.3 Liver Regeneration; 1.13 Megakaryocytes; 1.13.1 Mechanisms of MKC Polyploidization; 1.14 Concluding Remarks; Acknowledgments; References.
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|a Chapter 2 Large-Scale Programmed Genome Rearrangements in Vertebrates2.1 Introduction; 2.1 Hagfish; 2.2.1 Content of Eliminated DNA; 2.2.2 Results and Mechanisms of Deletion; 2.3 Sea Lamprey; 2.3.1 Content of Eliminated DNA; 2.3.2 Results and Mechanisms of Deletion; 2.4 Zebra Finch; 2.4.1 Mechanisms of Deletion; 2.4.2 Content of Eliminated DNA; 2.5 Emerging Themes and Directions; 2.5.1 The Biological Function of PGR; 2.5.2 Mechanisms of Deletion; 2.5.3 Other Vertebrates?; References; Chapter 3 Chromosome Instability in Stem Cells; 3.1 Introduction; 3.2 Pluripotent Stem Cells.
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|a 3.2.1 Primate Embryonic Stem Cells3.2.2 Mouse Embryonic Stem Cells; 3.2.3 Parthenogenetic Embryonic Stem Cells; 3.2.4 Induced Pluripotent Stem Cells; 3.3 Somatic Stem Cells; 3.3.1 Mesenchymal Stem Cells; 3.3.2 Neural Stem Cells; 3.4 Mechanisms of Chromosomal Instability; 3.4.1 Dysfunction in the Spindle Assembly Checkpoints; 3.4.2 Defects of Microtubule Attachment to the Kinetochore; 3.4.3 Supernumerary Centrosomes; 3.4.4 Sister Chromatids Cohesion; 3.5 Mechanisms of Chromosomal Instability in Stem Cells; References; Part II Somatic Genome Variation in Plants.
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| 500 |
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|a Chapter 4 Mechanisms of Induced Inheritable Genome Variation in Flax.
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| 590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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| 650 |
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|a Genetic Variation.
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| 758 |
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|i has work:
|a Somatic Genome Variation (Text)
|1 https://id.oclc.org/worldcat/entity/E39PD3dh8K8HPVv67BjCyVfRx8
|4 https://id.oclc.org/worldcat/ontology/hasWork
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| 776 |
0 |
8 |
|i Print version:
|a Li, Xiu-Qing.
|t Somatic Genome Variation.
|d Somerset : John Wiley & Sons, Incorporated, ©2017
|z 9781118647066
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| 856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=4845308
|z Texto completo
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|n EBL4845308
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