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Systems Biology.
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Newark :
John Wiley & Sons, Incorporated,
2017.
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| Colección: | Advanced Biotechnology Ser.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Related Titles; Title Page; Copyright; Table of Contents; List of Contributors; About the Series Editors; Chapter 1: Integrative Analysis of Omics Data; Summary; 1.1 Introduction; 1.2 Omics Data and Their Measurement Platforms; 1.3 Data Processing: Quality Assessment, Quantification, Normalization, and Statistical Analysis; 1.4 Data Integration: From a List of Genes to Biological Meaning; 1.5 Outlook and Perspectives; References; Chapter 2: 13C Flux Analysis in Biotechnology and Medicine; 2.1 Introduction; 2.2 Theoretical Foundations of 13C MFA; 2.3 Metabolic Flux Analysis in Biotechnology.
- 2.4 Metabolic Flux Analysis in Medicine2.5 Emerging Challenges for 13C MFA; 2.6 Conclusion; Acknowledgments; Disclosure; References; Chapter 3: Metabolic Modeling for Design of Cell Factories; Summary; 3.1 Introduction; 3.2 Building and Refining Genome-Scale Metabolic Models; 3.3 Strain Design Algorithms; 3.4 Case Studies; 3.5 Conclusions; Acknowledgments; References; Chapter 4: Genome-Scale Metabolic Modeling and In silico Strain Design of Escherichia coli; 4.1 Introduction; 4.2 The COBRA Approach; 4.3 History of E. coli Metabolic Modeling.
- 4.4 In silico Model-Based Strain Design of E. coli Cell Factories4.5 Future Directions of Model-Guided Strain Design in E. coli; References; Chapter 5: Accelerating the Drug Development Pipeline with Genome-Scale Metabolic Network Reconstructions; Summary; 5.1 Introduction; 5.2 Metabolic Reconstructions in the Drug Development Pipeline; 5.3 Species-Level Microbial Reconstructions; 5.4 The Human Reconstruction; 5.5 Community Models; 5.6 Personalized Medicine; 5.7 Conclusion; References; Chapter 6: Computational Modeling of Microbial Communities; Summary; 6.1 Introduction; 6.2 Ecological Models.
- 6.3 Genome-Scale Metabolic Models6.4 Concluding Remarks; References; Chapter 7: Drug Targeting of the Human Microbiome; Summary; 7.1 Introduction; 7.2 The Human Microbiome; 7.3 Association of the Human Microbiome with Human Diseases; 7.4 Drug Targeting of the Human Microbiome; 7.5 Future Perspectives; 7.6 Concluding Remarks; Acknowledgments; References; Chapter 8: Toward Genome-Scale Models of Signal Transduction Networks; 8.1 Introduction; 8.2 The Potential of Network Reconstruction; 8.3 Information Transfer Networks; 8.4 Approaches to Reconstruction of ITNs; 8.5 The rxncon Approach to ITNWR.