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Interpretation of MS-MS Mass Spectra of Drugs and Pesticides.
Provides comprehensive coverage of the interpretation of LC-MS-MS mass spectra of 1300 drugs and pesticides -Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes -This is the reference book for th...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Somerset :
John Wiley & Sons, Incorporated,
2017.
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| Colección: | Wiley-Interscience series on mass spectrometry.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000Mu 4500 | ||
|---|---|---|---|
| 001 | EBOOKCENTRAL_ocn968738104 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
| 006 | m o d | ||
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| 008 | 170114s2017 xx ob 001 0 eng d | ||
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| 020 | |a 9781119294245 | ||
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| 020 | |a 1118500180 |q (cloth) | ||
| 020 | |a 9781118500187 | ||
| 020 | |z 9781118500187 | ||
| 029 | 1 | |a AU@ |b 000059646288 | |
| 035 | |a (OCoLC)968738104 |z (OCoLC)974635173 |z (OCoLC)1148153048 | ||
| 050 | 4 | |a QD96.M3 |b N525 2017eb | |
| 082 | 0 | 4 | |a 543/.65 |2 23 |
| 049 | |a UAMI | ||
| 100 | 1 | |a Niessen, W. M. A. | |
| 245 | 1 | 0 | |a Interpretation of MS-MS Mass Spectra of Drugs and Pesticides. |
| 260 | |a Somerset : |b John Wiley & Sons, Incorporated, |c 2017. | ||
| 300 | |a 1 online resource (412 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Wiley Series on Mass Spectrometry | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Cover; Title Page; Copyright; Contents; Preface; Abbreviations; Chapter 1 Introduction to LC-MS Technology; 1.1 Introduction; 1.2 Analyte Ionization: Ion Sources; 1.2.1 Electron Ionization; 1.2.2 Chemical Ionization; 1.2.3 Atmospheric-Pressure Ionization; 1.2.4 Electrospray Ionization; 1.2.5 Atmospheric-Pressure Chemical Ionization and Photoionization; 1.2.6 Other Ionization Techniques; 1.3 Mass Spectrometer Building Blocks; 1.3.1 Introduction; 1.3.2 Quadrupole Mass Analyzer; 1.3.3 Ion-Trap Mass Analyzer; 1.3.4 Time-of-Flight Mass Analyzer; 1.3.5 Orbitrap Mass Analyzer. | |
| 505 | 8 | |a 1.3.6 Other Mass Analyzers1.4 Tandem Mass Spectrometry; 1.4.1 Introduction; 1.4.2 Tandem Quadrupole Instruments; 1.4.3 Ion-Trap Instruments; 1.4.4 Quadrupole-Linear Ion-Trap Hybrid Instruments; 1.4.5 Quadrupole-Time-of-Flight Hybrid Instruments; 1.4.6 Orbitrap Hybrid Instruments for MS-MS and MSn; 1.4.7 Other Instruments for MS-MS and MSn; 1.4.8 MS-MS and MSn in the Analysis of Drugs and Pesticides; 1.5 Data Acquisition; 1.5.1 Introduction; 1.5.2 Selected-Ion and Selected-Reaction Monitoring; 1.5.3 Structure-Specific Screening: Precursor-Ion and Neutral-Loss Analysis. | |
| 505 | 8 | |a 1.5.4 Data-Dependent Acquisition1.5.5 Data-Independent Acquisition; 1.6 Selected Literature on Mass Spectrometry; References; Chapter 2 Interpretation of Mass Spectra; 2.1 Mass Spectrometry: A Nuclear Affair; 2.2 Isomers, Isotones, Isobars, Isotopes; 2.3 Masses in MS; 2.4 Isotopes and Structure Elucidation; 2.5 Nitrogen Rule, Ring Double-Bond Equivalent, and Hydrogen Rule; 2.6 Resolving Power, Resolution, Accuracy; 2.7 Calculating Elemental Composition from Accurate m/z; 2.8 Protonated and Deprotonated Molecules and Adduct Ions; References; Chapter 3 Fragmentation of Even-Electron Ions. | |
| 505 | 8 | |a 3.1 Introduction3.2 Analyte Ionization Revisited; 3.3 Fragmentation of Odd-electron Ions; 3.4 High-energy Collisions of Protonated Molecules; 3.4.1 General Aspects; 3.4.2 Selected Examples; 3.5 Fragmentation of Protonated Molecules; 3.5.1 Singly-Charged Peptides; 3.5.2 Protonated Small Molecules: Complementary Fragment Ions; 3.5.3 Fragmentation of Peptides Revisited; 3.5.4 Direct-Cleavage Reactions; 3.5.5 Consecutive Small-Molecule Losses; 3.5.6 Other Fragmentation Reactions; 3.5.7 Loss of Radicals from Even-Electron Ions; 3.5.8 Skeletal Rearrangements in Protonated Molecules. | |
| 505 | 8 | |a 3.6 Characteristic Positive-ion Fragmentation of Functional Groups3.6.1 Cleavages of C-C Bonds; 3.6.2 Alcohols and Ethers; 3.6.3 Aldehydes and Ketones; 3.6.4 Carboxylic Acids and Esters; 3.6.5 Amines and Quaternary Ammonium Compounds; 3.6.6 Amides, Sulfonyl Ureas, and Carbamates; 3.6.7 Compounds Containing Phosphorus or Sulfur; 3.6.8 Miscellaneous Compound Classes; 3.7 Fragmentation of Deprotonated Molecules; 3.7.1 High-Energy CID with NICI-Generated Deprotonated Molecules; 3.7.2 General Aspects; 3.7.3 Alcohols and Ethers; 3.7.4 Carboxylic Acid and Esters; 3.7.5 Amines; 3.7.6 Amides and Ureas. | |
| 500 | |a 3.7.7 Sulfonamides and Related Sulfones. | ||
| 520 | |a Provides comprehensive coverage of the interpretation of LC-MS-MS mass spectra of 1300 drugs and pesticides -Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes -This is the reference book for the interpretation of MS-MS mass spectra of small organic molecules -Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others -Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups -Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns. | ||
| 504 | |a Includes bibliographical references at the end of each chapters and index. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Tandem mass spectrometry. | |
| 650 | 0 | |a Liquid chromatography. | |
| 650 | 0 | |a Drugs |x Analysis. | |
| 650 | 0 | |a Pesticides |x Analysis. | |
| 650 | 6 | |a Spectrométrie de masse en tandem. | |
| 650 | 6 | |a Chromatographie en phase liquide. | |
| 650 | 6 | |a Médicaments |x Analyse. | |
| 650 | 6 | |a Pesticides |x Analyse. | |
| 650 | 7 | |a liquid chromatography. |2 aat | |
| 650 | 7 | |a SCIENCE |x Spectroscopy & Spectrum Analysis. |2 bisacsh | |
| 650 | 7 | |a Drugs |x Analysis |2 fast | |
| 650 | 7 | |a Liquid chromatography |2 fast | |
| 650 | 7 | |a Pesticides |x Analysis |2 fast | |
| 650 | 7 | |a Tandem mass spectrometry |2 fast | |
| 700 | 1 | |a Correa C., R. A. | |
| 758 | |i has work: |a Interpretation of MS mass spectra of drugs and pesticides (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFGPTFV478bXqKq476KFBq |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Niessen, W.M.A. |t Interpretation of MS-MS Mass Spectra of Drugs and Pesticides. |d Somerset : John Wiley & Sons, Incorporated, ©2017 |z 9781118500187 |
| 830 | 0 | |a Wiley-Interscience series on mass spectrometry. | |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=4778036 |z Texto completo |
| 938 | |a Askews and Holts Library Services |b ASKH |n AH30712779 | ||
| 938 | |a Askews and Holts Library Services |b ASKH |n AH30712778 | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL4778036 | ||
| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n cis34407414 | ||
| 938 | |a Recorded Books, LLC |b RECE |n rbeEB00744658 | ||
| 994 | |a 92 |b IZTAP | ||