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Fossil Parasites.
Fossil Parasites, the latest edition in the Advances in Parasitology series established in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology, including medical studies of parasites of major influence, such as plasmodium falciparum and trypanoso...
| Clasificación: | Libro Electrónico |
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| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Elsevier Science
2015.
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| Colección: | Advances in parasitology.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Parasitology; Series Editor; Advances in ParasitologyEdited byD. RollinsonLife Sciences Department The Natural History Museum London, UKJ. R. StothardDe ... ; Copyright; Contents; Contributors; Recent Developments in Malaria Vaccinology; 1. Introduction; 2. Whole Sporozoite Vaccination; 2.1 Radiation-attenuated sporozoites; 2.2 Genetically attenuated parasites; 2.3 Infection-treatment vaccination/chemical prophylaxis sporozoite vaccination; 2.4 Immune responses to WSV; 3. Subunit Vaccines; 3.1 Pre-erythrocytic subunit vaccines; 3.1.1 RTS, S.
- 3.1.2 Liver-stage subunit vaccines3.2 Blood-stage subunit vaccines; 3.3 Transmission-blocking vaccines/mosquito stage vaccines; 4. Concluding Remarks; 4. 4Concluding RemarksThe malaria vaccine field has come a long way in recent times. Unlike the fields of HIV and TB vaccine d ... ; Competing Interest StatementBRH is a named inventor on a patent application covering molecular adjuvants. SJD is a named inv ... ; References; PfEMP1
- A Parasite Protein Family of Key Importance in Plasmodium falciparum Malaria Immunity and Pathogenesis; 1. Introduction.
- 2. The Structure of var Genes and PfEMP1 Proteins2.1 Primary structure; 2.2 Secondary structure; 2.3 Tertiary structure; 2.4 Quaternary structure; 3. The Function of PfEMP1; 3.1 Type 3 PfEMP1; 3.2 DC4-type PfEMP1; 3.3 DC5-type PfEMP1; 3.4 DC8- and DC13-type PfEMP1; 3.5 VAR2CSA-type PfEMP1; 3.6 Non-DC4-mediated adhesion of PfEMP1 to ICAM-1; 3.7 PfEMP1-mediated adhesion of IEs to CD36; 3.8 PfEMP1 and rosetting; 3.9 PfEMP1 and gametocytes; 4. Structural Organization of PfEMP1 at the IE Surface; 5. Regulation of var Gene Transcription and Switching; 5.1 Transcription of var genes.
- 5.2 Switching transcription from one var gene to another6. PfEMP1-Mediated Pathogenesis; 6.1 Cerebral malaria; 6.2 Placental malaria; 7. PfEMP1-Specific Immune Responses; 8. PfEMP1 and Vaccination against Malaria; 9. Conclusions and Future Directions; Acknowledgements; References; Prospects for Vector-Based Gene Silencing to Explore Immunobiological Features of Schistosoma mansoni; 1. Introduction; 2. Immune Responses and Pathological Changes during S. mansoni Infection; 3. The S. mansoni Egg and Its Antigens; 4. Major SEA Components Involved in Immunomodulation.
- 5. The RNAi Pathway and Machinery6. Previous Applications of RNAi to S. mansoni; 7. Application of a Lentiviral shRNAmir-Expression System to Explore Knockdown Effects on S. mansoni Egg-Induced Immune Respon ... ; 8. Advantages of Harnessing the miRNA Pathway; 9. Future Focus on S. mansoni Egg-Induced Immune Responses; 10. Designing Nonpathogenic Transgenic Schistosomes; 11. Concluding Remarks; Glossary; Acknowledgements; References; Chronobiology of Trematode Cercarial Emergence: from Data Recovery to Epidemiological, Ecological and Evolutionary Implications; 1. Introduction.