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|a Fossil Parasites.
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|c 2015.
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|a Advances in Parasitology ;
|v v. 89
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|a Fossil Parasites, the latest edition in the Advances in Parasitology series established in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology, including medical studies of parasites of major influence, such as plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. Parasitism is a dominant life history strategy and we know it has existed for millions of years. Detecting parasitism in the fossil record is problematic because we rarely see direct evidence and usually must rely on indirect evidence to infer its existence. This unique volume takes a broad and systematic view of direct and indirect evidence for parasitism in the fossil record. Expert contributors providing timely reviews of different aspects of palaeoparasitology Comprehensive treatments of taxonomic groups never before summarized Comprehensive coverage of important historical and recent advances in the field New avenues for research are explored and suggested.
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|a Vendor-supplied metadata.
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|a Front Cover; Advances in Parasitology; Series Editor; Advances in ParasitologyEdited byD. RollinsonLife Sciences Department The Natural History Museum London, UKJ. R. StothardDe ... ; Copyright; Contents; Contributors; Recent Developments in Malaria Vaccinology; 1. Introduction; 2. Whole Sporozoite Vaccination; 2.1 Radiation-attenuated sporozoites; 2.2 Genetically attenuated parasites; 2.3 Infection-treatment vaccination/chemical prophylaxis sporozoite vaccination; 2.4 Immune responses to WSV; 3. Subunit Vaccines; 3.1 Pre-erythrocytic subunit vaccines; 3.1.1 RTS, S.
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|a 3.1.2 Liver-stage subunit vaccines3.2 Blood-stage subunit vaccines; 3.3 Transmission-blocking vaccines/mosquito stage vaccines; 4. Concluding Remarks; 4. 4Concluding RemarksThe malaria vaccine field has come a long way in recent times. Unlike the fields of HIV and TB vaccine d ... ; Competing Interest StatementBRH is a named inventor on a patent application covering molecular adjuvants. SJD is a named inv ... ; References; PfEMP1 -- A Parasite Protein Family of Key Importance in Plasmodium falciparum Malaria Immunity and Pathogenesis; 1. Introduction.
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|a 2. The Structure of var Genes and PfEMP1 Proteins2.1 Primary structure; 2.2 Secondary structure; 2.3 Tertiary structure; 2.4 Quaternary structure; 3. The Function of PfEMP1; 3.1 Type 3 PfEMP1; 3.2 DC4-type PfEMP1; 3.3 DC5-type PfEMP1; 3.4 DC8- and DC13-type PfEMP1; 3.5 VAR2CSA-type PfEMP1; 3.6 Non-DC4-mediated adhesion of PfEMP1 to ICAM-1; 3.7 PfEMP1-mediated adhesion of IEs to CD36; 3.8 PfEMP1 and rosetting; 3.9 PfEMP1 and gametocytes; 4. Structural Organization of PfEMP1 at the IE Surface; 5. Regulation of var Gene Transcription and Switching; 5.1 Transcription of var genes.
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|a 5.2 Switching transcription from one var gene to another6. PfEMP1-Mediated Pathogenesis; 6.1 Cerebral malaria; 6.2 Placental malaria; 7. PfEMP1-Specific Immune Responses; 8. PfEMP1 and Vaccination against Malaria; 9. Conclusions and Future Directions; Acknowledgements; References; Prospects for Vector-Based Gene Silencing to Explore Immunobiological Features of Schistosoma mansoni; 1. Introduction; 2. Immune Responses and Pathological Changes during S. mansoni Infection; 3. The S. mansoni Egg and Its Antigens; 4. Major SEA Components Involved in Immunomodulation.
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|a 5. The RNAi Pathway and Machinery6. Previous Applications of RNAi to S. mansoni; 7. Application of a Lentiviral shRNAmir-Expression System to Explore Knockdown Effects on S. mansoni Egg-Induced Immune Respon ... ; 8. Advantages of Harnessing the miRNA Pathway; 9. Future Focus on S. mansoni Egg-Induced Immune Responses; 10. Designing Nonpathogenic Transgenic Schistosomes; 11. Concluding Remarks; Glossary; Acknowledgements; References; Chronobiology of Trematode Cercarial Emergence: from Data Recovery to Epidemiological, Ecological and Evolutionary Implications; 1. Introduction.
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|a Includes bibliographical references and index.
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|a Parasitology.
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|i has work:
|a Fossil Parasites (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCH8fcbqqdTxcFtVTwd4pKb
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|i Print version:
|a Littlewood, Tim.
|t Fossil parasites.
|d [Place of publication not identified] : Elsevier Academic Press, 2015
|z 0128033010
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