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Wiley IUBMB : Recent Advances in Malaria.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Chauhan, V.
Otros Autores: Chitnis, Chetan, Gaur, Deepak
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Somerset : John Wiley & Sons, Incorporated, 2016.
Temas:
Acceso en línea:Texto completo

MARC

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245 1 0 |a Wiley IUBMB :  |b Recent Advances in Malaria. 
260 |a Somerset :  |b John Wiley & Sons, Incorporated,  |c 2016. 
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505 0 |a Title Page ; Copyright Page; Contents; List ofÈcontributors; Foreword; Preface; Chapter 1 Introduction: An overview of malaria and Plasmodium ; History; The life cycle ofÈPlasmodium; A significant milestone inÈmalaria research: Adaptation ofÈPlasmodium toÈlaboratory culture; The advent of present-day technologies and their applications in malaria research ; Bibliography; Chapter 2 Exoerythrocytic development ofÈPlasmodiumÈparasites; The sporozoite's journey fromẗheÈskin toẗheÈliver; Sporozoite invasion; Parasite development; Protein export fromẗheÈparasite into theḧost cell. 
505 8 |a Parasite egressThe role ofïnnate immune responses during merosome formation; Acknowledgments; Bibliography; Chapter 3 Molecular basis of erythrocyte invasion by Plasmodium merozoites ; The structure ofẗheÈmerozoite; The steps ofërythrocyte invasion; Step 1: Initial attachment ofẗheÈmerozoite toẗheërythrocyte surface; Step 2: Apical reorientation; Step 3: Formation ofẗheÈjunction; Redundancy andÈligand-receptor interactions that mediate parasiteädhesion during erythrocyte invasion; Duffy binding-like family; Reticulocyte binding-like (RBL) family. 
505 8 |a Cooperativity between theÈDBL andÈRBL families ofÈproteinsIdentification ofÈnovel parasite ligands; Signaling events during erythrocyte invasion by malaria parasites; Summary andÈconclusions; Bibliography; Chapter 4 The biology ofÈmalaria transmission; Purpose; History; The current research agenda; Biology; Parasite; Vector; Vertebrate host; Population dynamics; Parasite dynamics inẗheÈmosquito; Transmission-blocking interventions ; Anti-vector strategies ; Anti-parasitic transmission-blocking interventions ; Bibliography; Chapter 5 Comparative and functional genomics of malaria parasites. 
505 8 |a An Introduction toÈPlasmodium genomesGenome structure ofÈmalaria parasites; Base content; Genome size andÈcomposition; Chromosome structure; Lineage-specific gene families ; From genome sequences toÈgene function; Genetic mapping; Population genomics toïdentify vaccine or drug targets; Global analysis ofẗranscripts; Epigenomics; Reverse genetics andÈparasite transformation; Summary; Acknowledgments; Bibliography; Chapter 6 Gene regulation: New insights and possible intervention strategies ; Introduction; Modes ofÈgene regulation; Epigenetic mechanisms ofÈgene regulation. 
505 8 |a Transcription factors and other DNA-binding proteins Alternative splicing; Post-transcriptional, translational, and post-translational gene regulation ; Drug targeting; Histone acetyltransferases (HATs); Histone deacetylases (HDACs); Histone methyltransferases; Histone demethylases; Histone kinases; Histone post-translational modification readers ; DNA methyltransferases; Perspectives; Bibliography; Chapter 7 Molecular genetic approaches to malaria research ; Transfection methods; Transient transfection; Stable transfection; Bxb1 integrase system; Genetic approaches forÈderiving gene function. 
500 |a Single crossover integration. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Malaria  |x Prevention. 
650 6 |a Paludisme  |x PrĐevention. 
650 7 |a Malaria  |x Prevention  |2 fast 
700 1 |a Chitnis, Chetan. 
700 1 |a Gaur, Deepak. 
776 0 8 |i Print version:  |a Chauhan, V.  |t Wiley IUBMB : Recent Advances in Malaria.  |d Somerset : John Wiley & Sons, Incorporated, Ã2016  |z 9781118493793 
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