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EBOOKCENTRAL_ocn965779501 |
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20240329122006.0 |
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161210s2016 xx o 000 0 eng d |
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|a EBLCP
|b eng
|e pn
|c EBLCP
|d OCLCQ
|d SGP
|d OCLCO
|d OCLCF
|d OCLCQ
|d OCLCO
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|a 9781118493830
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|a 1118493834
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|a AU@
|b 000059955611
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|a (OCoLC)965779501
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|a RC156
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|a WC 750
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|a 616.9362
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|a UAMI
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|a Chauhan, V.
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|a Wiley IUBMB :
|b Recent Advances in Malaria.
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|a Somerset :
|b John Wiley & Sons, Incorporated,
|c 2016.
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300 |
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|a 1 online resource (614 pages)
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a Title Page ; Copyright Page; Contents; List ofÈcontributors; Foreword; Preface; Chapter 1 Introduction: An overview of malaria and Plasmodium ; History; The life cycle ofÈPlasmodium; A significant milestone inÈmalaria research: Adaptation ofÈPlasmodium toÈlaboratory culture; The advent of present-day technologies and their applications in malaria research ; Bibliography; Chapter 2 Exoerythrocytic development ofÈPlasmodiumÈparasites; The sporozoite's journey fromẗheÈskin toẗheÈliver; Sporozoite invasion; Parasite development; Protein export fromẗheÈparasite into theḧost cell.
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|a Parasite egressThe role ofïnnate immune responses during merosome formation; Acknowledgments; Bibliography; Chapter 3 Molecular basis of erythrocyte invasion by Plasmodium merozoites ; The structure ofẗheÈmerozoite; The steps ofërythrocyte invasion; Step 1: Initial attachment ofẗheÈmerozoite toẗheërythrocyte surface; Step 2: Apical reorientation; Step 3: Formation ofẗheÈjunction; Redundancy andÈligand-receptor interactions that mediate parasiteädhesion during erythrocyte invasion; Duffy binding-like family; Reticulocyte binding-like (RBL) family.
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505 |
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|a Cooperativity between theÈDBL andÈRBL families ofÈproteinsIdentification ofÈnovel parasite ligands; Signaling events during erythrocyte invasion by malaria parasites; Summary andÈconclusions; Bibliography; Chapter 4 The biology ofÈmalaria transmission; Purpose; History; The current research agenda; Biology; Parasite; Vector; Vertebrate host; Population dynamics; Parasite dynamics inẗheÈmosquito; Transmission-blocking interventions ; Anti-vector strategies ; Anti-parasitic transmission-blocking interventions ; Bibliography; Chapter 5 Comparative and functional genomics of malaria parasites.
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505 |
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|a An Introduction toÈPlasmodium genomesGenome structure ofÈmalaria parasites; Base content; Genome size andÈcomposition; Chromosome structure; Lineage-specific gene families ; From genome sequences toÈgene function; Genetic mapping; Population genomics toïdentify vaccine or drug targets; Global analysis ofẗranscripts; Epigenomics; Reverse genetics andÈparasite transformation; Summary; Acknowledgments; Bibliography; Chapter 6 Gene regulation: New insights and possible intervention strategies ; Introduction; Modes ofÈgene regulation; Epigenetic mechanisms ofÈgene regulation.
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|a Transcription factors and other DNA-binding proteins Alternative splicing; Post-transcriptional, translational, and post-translational gene regulation ; Drug targeting; Histone acetyltransferases (HATs); Histone deacetylases (HDACs); Histone methyltransferases; Histone demethylases; Histone kinases; Histone post-translational modification readers ; DNA methyltransferases; Perspectives; Bibliography; Chapter 7 Molecular genetic approaches to malaria research ; Transfection methods; Transient transfection; Stable transfection; Bxb1 integrase system; Genetic approaches forÈderiving gene function.
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500 |
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|a Single crossover integration.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Malaria
|x Prevention.
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650 |
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6 |
|a Paludisme
|x PrĐevention.
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650 |
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7 |
|a Malaria
|x Prevention
|2 fast
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700 |
1 |
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|a Chitnis, Chetan.
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700 |
1 |
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|a Gaur, Deepak.
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776 |
0 |
8 |
|i Print version:
|a Chauhan, V.
|t Wiley IUBMB : Recent Advances in Malaria.
|d Somerset : John Wiley & Sons, Incorporated, Ã2016
|z 9781118493793
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856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=4756772
|z Texto completo
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938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL4756772
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994 |
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|a 92
|b IZTAP
|