Antibody-Drug Conjugates : Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer.

Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. - Discusses the basics, drug delivery strategies, pharmacology and toxicology,...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Olivier, Kenneth J.
Otros Autores: Hurvitz, Sara A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : John Wiley & Sons, Incorporated, 2016.
Temas:
Antibody-toxin conjugates.
Monoclonal antibodies.
Antineoplastic agents.
Tumors > Treatment.
Antimitotic agents.
Immunoconjugates
Immunotoxins
Antibodies, Monoclonal
Antimitotic Agents
Antineoplastic Agents
Conjugués antitoxines.
Anticorps monoclonaux.
Anticancéreux.
Tumeurs > Traitement.
MEDICAL > Pharmacology.
Antimitotic agents
Antibody-toxin conjugates
Antineoplastic agents
Monoclonal antibodies
Tumors > Treatment
Acceso en línea:Texto completo
Descripción
Sumario:Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. - Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies- Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging- Includes case studies of ADCs in oncology drug development- Features contributions from highly-regarded experts on the frontlines of ADC research and development.
Notas:4.9 Linkers to Optimize for Drug Resistance.
Descripción Física:1 online resource (566 pages)
ISBN:9781119060802
111906080X

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