Cargando…
Developing Solid Oral Dosage Forms : Pharmaceutical Theory and Practice.
Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Otros Autores: | , , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Saint Louis :
Elsevier Science,
2016.
|
| Edición: | 2nd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
|---|---|---|---|
| 001 | EBOOKCENTRAL_ocn963586572 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
| 006 | m o d | ||
| 007 | cr |n|---||||| | ||
| 008 | 161119s2016 mou o 000 0 eng d | ||
| 040 | |a EBLCP |b eng |e pn |c EBLCP |d OCLCQ |d U3G |d OCLCO |d OCLCF |d OCLCQ |d UKMGB |d OCLCQ |d VRC |d OCLCO |d K6U |d OCLCQ |d OCL |d OCLCO |d OCLCL | ||
| 015 | |a GBB6F9098 |2 bnb | ||
| 016 | 7 | |a 018105036 |2 Uk | |
| 020 | |a 9780128026373 | ||
| 020 | |a 0128026375 | ||
| 020 | |a 012802447X | ||
| 020 | |a 9780128024478 | ||
| 029 | 1 | |a UKMGB |b 018105036 | |
| 035 | |a (OCoLC)963586572 | ||
| 037 | |a 9780128026373 |b Ingram Content Group | ||
| 050 | 4 | |a RS201.S57 |b D48 2016eb | |
| 082 | 0 | 4 | |a 615.19 |
| 049 | |a UAMI | ||
| 100 | 1 | |a Qiu, Yihong. | |
| 245 | 1 | 0 | |a Developing Solid Oral Dosage Forms : |b Pharmaceutical Theory and Practice. |
| 250 | |a 2nd ed. | ||
| 260 | |a Saint Louis : |b Elsevier Science, |c 2016. | ||
| 300 | |a 1 online resource (1176 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; Developing Solid Oral Dosage Forms; Copyright Page; Dedication; Contents; List of Contributors; I. Theories and Techniques in the Characterization of Drug Substances and Excipients; 1 Solubility of Pharmaceutical Solids; 1.1 Introduction; 1.1.1 Implication of solubility in dosage form development; 1.1.2 Basic concepts of solubility and dissolution; 1.1.2.1 Ionic interactions; 1.1.2.2 van der Waals interactions; 1.1.2.3 Dispersion interactions; 1.1.2.4 Hydrogen bonding; 1.2 Thermodynamics of Solutions; 1.2.1 Volume of mixing; 1.2.2 Enthalpy of mixing; 1.2.3 Entropy of mixing. | |
| 505 | 8 | |a 1.2.4 Free energy of mixing1.3 Theoretical Estimation of Solubility; 1.3.1 Ideal solutions; 1.3.2 Effect of crystallinity; 1.3.3 Nonideal solutions; 1.3.4 Regular solution theory; 1.3.5 Aqueous solution theory; 1.3.6 General solubility equation; 1.4 Solubilization of Drug Candidates; 1.4.1 Solubility enhancement by pH control and salt formation; 1.4.1.1 Theoretical expressions to describe pH-solubility profiles; 1.4.2 Solubilization using complexation; 1.4.2.1 AL-type phase diagrams; 1.4.2.2 AP-type phase diagrams; 1.4.2.3 BS-type phase diagrams; 1.4.3 Solubilization by cosolvents. | |
| 505 | 8 | |a 1.4.4 Solubilization by surfactants (micellar solubilization)1.4.5 Solubilization by combination of approaches; 1.4.5.1 Combined effect of ionization and cosolvency; 1.4.5.2 Combined effect of ionization and micellization; 1.4.5.3 Combined effect of ionization and complexation; 1.4.5.4 Combined effect of cosolvency and complexation; 1.4.5.5 Combined effect of complexation and micellar solubilization; 1.5 Experimental Determination of Solubility; 1.5.1 Stability of solute and solvent; 1.5.2 Shakers and containers; 1.5.3 Presence of excess undissolved solute; 1.5.4 Determination of equilibrium. | |
| 505 | 8 | |a 1.5.5 Phase separation1.5.6 Determination of solute content in the dissolved phase; 1.5.7 Experimental conditions; References; 2 Crystalline and Amorphous Solids; 2.1 Introduction; 2.2 Definitions and Categorization of Solids; 2.3 Thermodynamics and Phase Diagrams; 2.3.1 Polymorphs; 2.3.1.1 Enantiotropy and monotropy; 2.3.1.2 Methods of determining stability relationships between polymorphs; 2.3.1.2.1 Quantitative methods; 2.3.1.2.1.1 Using heat of fusion data; 2.3.1.2.1.2 Using eutectic fusion data; 2.3.1.2.1.3 Using solubility/intrinsic dissolution rate data. | |
| 505 | 8 | |a 2.3.1.2.1.4 Using solubility/intrinsic dissolution rate and heat of solution data2.3.1.2.2 Qualitative methods; 2.3.1.2.2.1 Using the definition; 2.3.1.2.2.2 Using the heat of fusion rule; 2.3.1.2.2.3 Using the heat of transition rule; 2.3.2 Solvates/Hydrates; 2.3.2.1 Anhydrate/Hydrate equilibrium at constant temperature; 2.3.2.2 Temperature dependence of anhydrate/hydrate equilibrium; 2.3.3 Cocrystals; 2.3.4 Amorphous solids; 2.4 Pharmaceutical Relevance and Implications; 2.4.1 Solubility; 2.4.2 Dissolution rate and bioavailability; 2.4.3 Hygroscopicity. | |
| 500 | |a 2.4.4 Reactivity and chemical stability. | ||
| 520 | |a Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Solid dosage forms |x Research. | |
| 650 | 0 | |a Solid dosage forms. | |
| 650 | 0 | |a Drugs |x Dosage forms. | |
| 650 | 0 | |a Oral medication. | |
| 650 | 1 | 2 | |a Dosage Forms |
| 650 | 1 | 2 | |a Drug Delivery Systems |x methods |
| 650 | 2 | 2 | |a Administration, Oral |
| 650 | 6 | |a Médicaments |x Formes pharmaceutiques solides |x Recherche. | |
| 650 | 6 | |a Médicaments |x Formes pharmaceutiques solides. | |
| 650 | 6 | |a Médicaments |x Formes pharmaceutiques. | |
| 650 | 6 | |a Médicaments |x Administration par voie orale. | |
| 650 | 7 | |a Oral medication |2 fast | |
| 650 | 7 | |a Drugs |x Dosage forms |2 fast | |
| 650 | 7 | |a Solid dosage forms |2 fast | |
| 700 | 1 | |a Chen, Yisheng. | |
| 700 | 1 | |a Zhang, Geoff G. Z. | |
| 700 | 1 | |a Yu, Lawrence. | |
| 700 | 1 | |a Mantri, Rao V. | |
| 758 | |i has work: |a Developing solid oral dosage forms (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFwRJKh8PpwtCpx69Q4tXd |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Qiu, Yihong. |t Developing Solid Oral Dosage Forms : Pharmaceutical Theory and Practice. |d Saint Louis : Elsevier Science, ©2016 |z 9780128024478 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=4737247 |z Texto completo |
| 936 | |a BATCHLOAD | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL4737247 | ||
| 994 | |a 92 |b IZTAP | ||