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Prions and prion diseases : new developments /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Verdier, Jean-Michel (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Biomedical/Nova Science Publishers, Inc., [2012]
Colección:Protein biochemistry, synthesis, structure, and cellular functions series.
Protein science and engineering.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Prions and prion diseases :  |b new developments /  |c Jean-Michel Verdier, editor. 
264 1 |a New York :  |b Nova Biomedical/Nova Science Publishers, Inc.,  |c [2012] 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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490 1 |a Protein biochemistry, synthesis, structure, and cellular functions 
490 1 |a Protein science and engineering 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a PRIONS AND PRION DISEASES -- PRIONS AND PRION DISEASES -- CONTENTS -- PREFACE -- NEUROPATHOLOGY OF HUMAN PRION DISEASES -- ABSTRACT -- INTRODUCTION -- THE ROLE OF NEUROPATHOLOGY -- PERFORMING THE AUTOPSY -- NEUROPATHOLOGICAL EXAMINATION -- A.) Macroscopy -- B.) Work-Up for Histological Evaluation -- C.) Microscopic Assessment -- I.) Spongiform Change of the Neuropil -- a) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- II) Neuronal Death -- a.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms 
505 8 |a SYNAPTIC PATHOLOGY III.) Astroglial Proliferation -- IV.) Microglial Activation -- V.) PrP Amyloid Plaques -- a.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- VI.) Cerebellar Pathology -- a.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- RELATIVE RESISTANCE OF HIPPOCAMPUS IN CJD -- VII.) Detection of PrP -- VIIa.) By Immunohistochemistry -- a.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- VIIb.) By histoblot and Paraffin-Embedded Tissue Blot 
505 8 |a VIId.) By Western blota.) In Sporadic Forms -- b.) In Genetic Forms -- c.) In Acquired Forms -- VIII.) Co-deposition of other Abnormal Protein Aggregates in CJD -- a) In Sporadic Forms -- b) In Genetic Forms -- c) In Acquired Forms -- IX.) Differential Diagnoses from Autopsy Series -- X.) Neuronal Systems and Their Clinico-Pathological Correlates -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- THE NATURE OF THE INFECTIOUS AGENTS: PRP MODELS OF RESISTANT SPECIES TO PRION DISEASES (DOG, RABBIT AND HORSES) -- Abstract -- 1. Introduction 
505 8 |a 2. MaterialsandMethods3. ResultsandDiscussion -- 4. Conclusion -- Acknowledgments -- References -- INDUCING TRANSMISSIBLE PRION DISEASES WITH RECOMBINANT FIBRILS: A NEW CONCEPT ON GENESIS AND EVOLUTION OF INFECTIOUS PRIONS -- ABSTRACT -- GENERATING TRANSMISSIBLE PRION DISEASES DE NOVO -- THE MECHANISM OF TRIGGERING PRION DISEASE BY RPRP AMYLOID FIBRILS -- EXPERIMENTAL EVIDENCE SUPPORT THE SECOND MODEL -- THE HYPOTHESIS OF DEFORMED TEMPLATING -- CONFORMATIONAL SWITCHING WITHIN INDIVIDUAL AMYLOID FIBRILS AND STRAIN ADAPTATION PHENOMENON 
505 8 |a CROSS-TALK BETWEEN AMYLOIDOGENIC PROTEINS REFERENCES -- SYNTHETIC PRIONS -- ABSTRACT -- 1. INTRODUCTION -- 2. STRATEGIES FOR DE NOVO MAMMALIAN PRIONS GENERATION -- 2.1. Cell-Free Assay Using Mammalian Prions -- 2.2. De Novo Generation of Prions by Mouse Transgenesis -- 2.3. In Vitro De Novo Prions by PMCA -- 2.4. De Novo Prions by Amyloid Seeding Assay -- 2.5. De Novo Prions by Annealing Technique -- 2.6. Concluding Remarks and New Emerging Techniques for Prion Detection and Generation -- 3. STRUCTURAL BIOLOGY OF NATURAL AND SYNTHETIC PRIONS 
546 |a English. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Prions. 
650 0 |a Prion diseases. 
650 6 |a Prions (Virologie) 
650 6 |a Maladies à prions. 
650 7 |a SCIENCE  |x Life Sciences  |x Biology.  |2 bisacsh 
650 7 |a SCIENCE  |x Life Sciences  |x Microbiology.  |2 bisacsh 
650 7 |a Prion diseases  |2 fast 
650 7 |a Prions  |2 fast 
700 1 |a Verdier, Jean-Michel,  |e editor. 
758 |i has work:  |a Prions and prion diseases (Text)  |1 https://id.oclc.org/worldcat/entity/E39PD33f33kPtFPvGKJpgwW8P3  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |t Prions and prion diseases.  |d New York : Nova Biomedical/Nova Science Publishers, Inc., [2012]  |z 9781621000273  |w (DLC) 2011946079 
830 0 |a Protein biochemistry, synthesis, structure, and cellular functions series. 
830 0 |a Protein science and engineering. 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=3017951  |z Texto completo 
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