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|a Neurodegenerative diseases :
|b unifying principles /
|c edited by Jeffrey L. Cummings, Jagan A. Pillai.
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|a Oxford ;
|a New York :
|b Oxford University Press,
|c [2017]
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|a 1 online resource (xi, 346 pages) :
|b illustrations
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|a Includes bibliographical references and index.
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|a Neurodegenerative diseases : evolving unifying principles / Jeffrey Cummings and Jagan Pillai -- Neurodegenerative diseases as protein misfolding disorders / Tomohiro Nakamura and Stuart A. Lipton -- Calcium hypothesis on neurodegeneration : the case of AD and HD / Daniel A. Ryskamp, Elena Popugaeva, and Ilya Bezprozvanny -- Inflammation in neurodegenerative diseases / Bruce Lamb -- Prion paradigm of human neurodegenerative diseases caused by protein misfolding / Jiri Safar -- Neuropsychiatric features across neurodegenerative diseases / Claudia R. Padilla, Mario F. Mendez -- Brain circuits : pathway for NDD / William Seeley -- Fluid biomarkers indicative of neurodegenerative diseases / Henrik Zetterberg and Jonathan M. Schott -- Predementia disorders : neurodegenerative diseases predecessor states as unifying clinical features / Jagan Pillai -- Genetics of neurodegenerative diseases : sporadic and autosomal dominant forms / Lars Bertram and Max Planck -- An epigenetics perspective on diseases of the central nervous system / Diego Mastroeni -- Mitochondrial changes and bioenergetics in neurodegenerative diseases / Andrew B. Knot and Ella Bossy-Wetzel -- Systems biology in neurodegenerative diseases / Lawrence Rajendran -- Cell culture and iPS cells and neurodegenerative diseases / Roxana Nat -- Animal models of neurodegenerative diseases / David Baglietto-Vargas, Ager RR, Medeiros R, and Frank M. LaFerla -- Metal-protein attenuating compounds in neurodegenerative diseases / Peng Lei, Scott Ayton, and Ashley I. Bush -- Disease modifying therapies in neurodegenerative disorders / Janelle Drouin-Ouellet and Roger A. Barker -- Immunotherapy for neurodegenerative disorders / David Morgan -- Clinical trials and drug development in neurodegenerative diseases : unifying principles / Jeffrey Cummings and Kate Zhong -- Conclusions on neurodegenerative disorders : unifying principles / Jagan Pillai and Jeffrey Cummings.
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|a Neurodegenerative Diseases: Unifying Principles is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the common biological and pathological features across seemingly varied neurodegenerative diseases that entail protein misfolding dysfunction and its consequences over time. Providing an overview of this conceptual change is the main theme for the book. Conventional approach emphasize the differences among neurodegenerative disorders, here Drs. Cummings and Pillai com.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Nervous system
|x Degeneration.
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650 |
1 |
2 |
|a Neurodegenerative Diseases
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650 |
|
7 |
|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
|
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7 |
|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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|a MEDICAL
|x Diseases.
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|a MEDICAL
|x Evidence-Based Medicine.
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|a MEDICAL
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|2 bisacsh
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650 |
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|a Nervous system
|x Degeneration
|2 fast
|
700 |
1 |
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|a Cummings, Jeffrey L.,
|d 1948-
|e editor.
|1 https://id.oclc.org/worldcat/entity/E39PBJkmYRvgfyXyvPqkR4gVG3
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700 |
1 |
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|a Pillai, Jagan,
|e editor.
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758 |
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|i has work:
|a Neurodegenerative diseases (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGkDTQFCrCJgPPTJKyQ8YP
|4 https://id.oclc.org/worldcat/ontology/hasWork
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|i Print version:
|t Neurodegenerative diseases.
|d Oxford ; New York : Oxford University Press, [2017]
|z 9780190233563
|w (DLC) 2015038313
|w (OCoLC)922666318
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